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Items: 1 to 20 of 143

1.

Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, Purushotham A, Li X.

Mol Cell Biol. 2010 Oct;30(19):4712-21. doi: 10.1128/MCB.00657-10.

2.

Myeloid deletion of SIRT1 aggravates serum transfer arthritis in mice via nuclear factor-κB activation.

Hah YS, Cheon YH, Lim HS, Cho HY, Park BH, Ka SO, Lee YR, Jeong DW, Kim HO, Han MK, Lee SI.

PLoS One. 2014 Feb 3;9(2):e87733. doi: 10.1371/journal.pone.0087733.

3.

Myeloid SIRT1 regulates macrophage infiltration and insulin sensitivity in mice fed a high-fat diet.

Ka SO, Song MY, Bae EJ, Park BH.

J Endocrinol. 2015 Feb;224(2):109-18. doi: 10.1530/JOE-14-0527.

4.

SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.

Yang H, Zhang W, Pan H, Feldser HG, Lainez E, Miller C, Leung S, Zhong Z, Zhao H, Sweitzer S, Considine T, Riera T, Suri V, White B, Ellis JL, Vlasuk GP, Loh C.

PLoS One. 2012;7(9):e46364. doi: 10.1371/journal.pone.0046364.

5.
6.

Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines.

Shen Z, Ajmo JM, Rogers CQ, Liang X, Le L, Murr MM, Peng Y, You M.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1047-53. doi: 10.1152/ajpgi.00016.2009.

7.

Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1.

Dong J, Zhang X, Zhang L, Bian HX, Xu N, Bao B, Liu J.

J Lipid Res. 2014 Mar;55(3):363-74. doi: 10.1194/jlr.M038786.

8.

SirT1 regulates adipose tissue inflammation.

Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI.

Diabetes. 2011 Dec;60(12):3235-45. doi: 10.2337/db11-0616.

9.

The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1.

Yang Z, Wang X, He Y, Qi L, Yu L, Xue B, Shi H.

PLoS One. 2012;7(11):e49935. doi: 10.1371/journal.pone.0049935.

10.

Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells.

Zhang HN, Li L, Gao P, Chen HZ, Zhang R, Wei YS, Liu DP, Liang CC.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):569-75. doi: 10.1016/j.bbrc.2010.05.160.

PMID:
20617556
11.

Myeloid-specific deletion of SIRT1 increases hepatic steatosis and hypothalamic inflammation in mice fed a high-fat diet.

Jeon BT, Kim KE, Heo RW, Shin HJ, Yi CO, Hah YS, Kim WH, Lee SI, Roh GS.

Metab Brain Dis. 2014 Sep;29(3):635-43. doi: 10.1007/s11011-014-9542-3.

PMID:
24756314
12.

Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway.

Kim HJ, Joe Y, Yu JK, Chen Y, Jeong SO, Mani N, Cho GJ, Pae HO, Ryter SW, Chung HT.

Biochim Biophys Acta. 2015 Jul;1852(7):1550-9. doi: 10.1016/j.bbadis.2015.04.017.

13.

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity.

Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E419-28. doi: 10.1152/ajpendo.00417.2009.

14.

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders.

Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A.

Cell Signal. 2013 Oct;25(10):1939-48. doi: 10.1016/j.cellsig.2013.06.007. Review.

PMID:
23770291
15.

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.

Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M.

Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375.

16.

Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts.

Zhu X, Liu Q, Wang M, Liang M, Yang X, Xu X, Zou H, Qiu J.

PLoS One. 2011;6(11):e27081. doi: 10.1371/journal.pone.0027081.

17.

The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.

Wang W, Bai L, Qiao H, Lu Y, Yang L, Zhang J, Lin R, Ren F, Zhang J, Ji M.

Inflammation. 2014 Feb;37(1):177-85.

PMID:
24022598
18.

The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway.

Zhang J, Zhang Y, Xiao F, Liu Y, Wang J, Gao H, Rong S, Yao Y, Li J, Xu G.

Biochem Pharmacol. 2016 Feb 1;101:100-11. doi: 10.1016/j.bcp.2015.11.027.

PMID:
26673543
19.
20.

Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1.

Yang Z, Kahn BB, Shi H, Xue BZ.

J Biol Chem. 2010 Jun 18;285(25):19051-9. doi: 10.1074/jbc.M110.123620.

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