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Items: 1 to 20 of 102

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Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. II. Gene array analysis reveals adaptive changes in cell cycle and cell death pathways.

Campion SN, Houseman EA, Sandrof MA, Hensley JB, Sui Y, Gaido KW, Wu Z, Boekelheide K.

Toxicol Sci. 2010 Oct;117(2):457-65. doi: 10.1093/toxsci/kfq204. Epub 2010 Jul 8.

4.

2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.

Markelewicz RJ Jr, Hall SJ, Boekelheide K.

Toxicol Sci. 2004 Jul;80(1):92-100. Epub 2004 May 12.

PMID:
15141104
5.

Fate of germ cells in 2,5-hexanedione-induced testicular injury. I. Apoptosis is the mechanism of germ cell death.

Blanchard KT, Allard EK, Boekelheide K.

Toxicol Appl Pharmacol. 1996 Apr;137(2):141-8.

PMID:
8661338
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2,5-Hexanedione exposure alters the rat Sertoli cell cytoskeleton. I. Microtubules and seminiferous tubule fluid secretion.

Johnson KJ, Hall ES, Boekelheide K.

Toxicol Appl Pharmacol. 1991 Dec;111(3):432-42.

PMID:
1746024
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Seminiferous tubule fluid secretion is a Sertoli cell microtubule-dependent process inhibited by 2,5-hexanedione exposure.

Richburg JH, Redenbach DM, Boekelheide K.

Toxicol Appl Pharmacol. 1994 Oct;128(2):302-9.

PMID:
7940545
12.

The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis.

Lee J, Richburg JH, Shipp EB, Meistrich ML, Boekelheide K.

Endocrinology. 1999 Feb;140(2):852-8.

PMID:
9927315
13.

Spermatid head retention as a marker of 2,5-hexanedione-induced testicular toxicity in the rat.

Bryant BH, Yamasaki H, Sandrof MA, Boekelheide K.

Toxicol Pathol. 2008 Jun;36(4):552-9. doi: 10.1177/0192623308317426. Epub 2008 May 8.

14.

During seminiferous tubule maturation testosterone and synergistic action of FSH with estradiol support germ cell survival while estradiol alone has pro-apoptotic effect.

Walczak-Jedrzejowska R, Slowikowska-Hilczer J, Marchlewsk K, Oszukowska E, Kula K.

Folia Histochem Cytobiol. 2007;45 Suppl 1:S59-64.

PMID:
18292837
15.

Disruption of spermatogenesis and Sertoli cell structure and function by the indenopyridine CDB-4022 in rats.

Hild SA, Reel JR, Larner JM, Blye RP.

Biol Reprod. 2001 Dec;65(6):1771-9.

PMID:
11717140
16.

Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand.

Richburg JH, Nañez A, Williams LR, Embree ME, Boekelheide K.

Endocrinology. 2000 Feb;141(2):787-93.

PMID:
10650961
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Resveratrol reestablishes spermatogenesis after testicular injury in rats caused by 2, 5-hexanedione.

Jiang YG, Peng T, Luo Y, Li MC, Lin YH.

Chin Med J (Engl). 2008 Jul 5;121(13):1204-9.

PMID:
18710639
20.

Sertoli cells isolated from adult 2,5-hexanedione-exposed rats exhibit atypical morphology and actin distribution.

Hall ES, Hall SJ, Boekelheide K.

Toxicol Appl Pharmacol. 1992 Nov;117(1):9-18. Erratum in: Toxicol Appl Pharmacol 1993 Apr;119(2):310.

PMID:
1359677

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