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Items: 1 to 20 of 411

1.

The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas.

Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB.

Cell Signal. 2010 Nov;22(11):1745-52. doi: 10.1016/j.cellsig.2010.06.015. Epub 2010 Jul 24.

2.

SHEP1 function in cell migration is impaired by a single amino acid mutation that disrupts association with the scaffolding protein cas but not with Ras GTPases.

Dail M, Kalo MS, Seddon JA, Côté JF, Vuori K, Pasquale EB.

J Biol Chem. 2004 Oct 1;279(40):41892-902. Epub 2004 Jul 22.

3.

Breast cancer anti-estrogen resistance 3 (BCAR3) protein augments binding of the c-Src SH3 domain to Crk-associated substrate (p130cas).

Makkinje A, Vanden Borre P, Near RI, Patel PS, Lerner A.

J Biol Chem. 2012 Aug 10;287(33):27703-14. doi: 10.1074/jbc.M112.389981. Epub 2012 Jun 18.

4.
5.

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB.

Oncogene. 2001 Feb 22;20(8):951-61.

6.

Molecular basis for regulation of Src by the docking protein p130Cas.

Nasertorabi F, Tars K, Becherer K, Kodandapani R, Liljas L, Vuori K, Ely KR.

J Mol Recognit. 2006 Jan-Feb;19(1):30-8.

PMID:
16245368
7.

Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals.

Antoku S, Mayer BJ.

J Cell Sci. 2009 Nov 15;122(Pt 22):4228-38. doi: 10.1242/jcs.054627. Epub 2009 Oct 27.

9.

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase.

Nakamoto T, Sakai R, Ozawa K, Yazaki Y, Hirai H.

J Biol Chem. 1996 Apr 12;271(15):8959-65.

10.

Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions.

Pellicena P, Miller WT.

J Biol Chem. 2001 Jul 27;276(30):28190-6. Epub 2001 Jun 1.

11.

Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice.

Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Z, Noda M, Miyasaka N, Sueda T, Honda H.

Genes Cells. 2008 Feb;13(2):145-57. doi: 10.1111/j.1365-2443.2007.01156.x.

12.

Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas.

Hamasaki K, Mimura T, Morino N, Furuya H, Nakamoto T, Aizawa S, Morimoto C, Yazaki Y, Hirai H, Nojima Y.

Biochem Biophys Res Commun. 1996 May 15;222(2):338-43.

PMID:
8670206
13.

p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.

Salgia R, Pisick E, Sattler M, Li JL, Uemura N, Wong WK, Burky SA, Hirai H, Chen LB, Griffin JD.

J Biol Chem. 1996 Oct 11;271(41):25198-203.

14.

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.

Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, Hanks SK.

J Biol Chem. 2004 Sep 10;279(37):38331-7. Epub 2004 Jul 6.

15.

Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src.

Ruest PJ, Shin NY, Polte TR, Zhang X, Hanks SK.

Mol Cell Biol. 2001 Nov;21(22):7641-52.

16.
17.

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs.

Nojima Y, Morino N, Mimura T, Hamasaki K, Furuya H, Sakai R, Sato T, Tachibana K, Morimoto C, Yazaki Y, et al.

J Biol Chem. 1995 Jun 23;270(25):15398-402.

18.

Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1.

Richard S, Yu D, Blumer KJ, Hausladen D, Olszowy MW, Connelly PA, Shaw AS.

Mol Cell Biol. 1995 Jan;15(1):186-97.

19.

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas.

Polte TR, Hanks SK.

Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10678-82.

20.

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway.

Dolfi F, Garcia-Guzman M, Ojaniemi M, Nakamura H, Matsuda M, Vuori K.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15394-9.

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