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Cytosolic FoxO1: alive and killing.

Medema RH, Jäättelä M.

Nat Cell Biol. 2010 Jul;12(7):642-3. doi: 10.1038/ncb0710-642.


Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity.

Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S, Wang D, Feng J, Yu L, Zhu WG.

Nat Cell Biol. 2010 Jul;12(7):665-75. doi: 10.1038/ncb2069.


Anti-neoplastic activity of the cytosolic FoxO1 results from autophagic cell death.

Zhao Y, Wang L, Yang J, Zhang P, Ma K, Zhou J, Liao W, Zhu WG.

Autophagy. 2010 Oct;6(7):988-90. doi: 10.4161/auto.6.7.13289.


Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression.

Liu J, Bi X, Chen T, Zhang Q, Wang SX, Chiu JJ, Liu GS, Zhang Y, Bu P, Jiang F.

Cell Death Dis. 2015 Jul 16;6:e1827. doi: 10.1038/cddis.2015.193.


Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage.

Han J, Pan XY, Xu Y, Xiao Y, An Y, Tie L, Pan Y, Li XJ.

Autophagy. 2012 May 1;8(5):812-25. doi: 10.4161/auto.19471.


FoxO1-mediated autophagy is required for NK cell development and innate immunity.

Wang S, Xia P, Huang G, Zhu P, Liu J, Ye B, Du Y, Fan Z.

Nat Commun. 2016 Mar 24;7:11023. doi: 10.1038/ncomms11023.


E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I.

Gao W, Chen Z, Wang W, Stang MT.

PLoS One. 2013 Sep 4;8(9):e73229. doi: 10.1371/journal.pone.0073229.


FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway.

Zhou J, Liao W, Yang J, Ma K, Li X, Wang Y, Wang D, Wang L, Zhang Y, Yin Y, Zhao Y, Zhu WG.

Autophagy. 2012 Dec;8(12):1712-23. doi: 10.4161/auto.21830.


Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism.

Wang N, Zimmerman K, Raab RW, McKown RL, Hutnik CM, Talla V, Tyler MF 4th, Lee JK, Laurie GW.

J Biol Chem. 2013 Jun 21;288(25):18146-61. doi: 10.1074/jbc.M112.436584.


CD47 deficiency confers cell and tissue radioprotection by activation of autophagy.

Soto-Pantoja DR, Miller TW, Pendrak ML, DeGraff WG, Sullivan C, Ridnour LA, Abu-Asab M, Wink DA, Tsokos M, Roberts DD.

Autophagy. 2012 Nov;8(11):1628-42. doi: 10.4161/auto.21562.


Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death.

Tang Y, Chen Y, Jiang H, Nie D.

Cell Death Differ. 2011 Apr;18(4):602-18. doi: 10.1038/cdd.2010.117.


Autophagy and p62/sequestosome 1 generate neo-antimicrobial peptides (cryptides) from cytosolic proteins.

Ponpuak M, Deretic V.

Autophagy. 2011 Mar;7(3):336-7. No abstract available.


Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1.

Mao W, You T, Ye B, Li X, Dong HH, Hill JA, Li F, Xu H.

PLoS One. 2012;7(2):e32738. doi: 10.1371/journal.pone.0032738.


Glucose-starved cells do not engage in prosurvival autophagy.

Ramírez-Peinado S, León-Annicchiarico CL, Galindo-Moreno J, Iurlaro R, Caro-Maldonado A, Prehn JH, Ryan KM, Muñoz-Pinedo C.

J Biol Chem. 2013 Oct 18;288(42):30387-98. doi: 10.1074/jbc.M113.490581.


Induction of autophagy does not alter the anti-tumor effects of HDAC inhibitors.

Newbold A, Vervoort SJ, Martin BP, Bots M, Johnstone RW.

Cell Death Dis. 2012 Sep 6;3:e387. doi: 10.1038/cddis.2012.128. No abstract available.


An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells.

Nihira K, Miki Y, Ono K, Suzuki T, Sasano H.

Cancer Sci. 2014 May;105(5):568-75. doi: 10.1111/cas.12396.


FOXO1 silence aggravates oxidative stress-promoted apoptosis in cardiomyocytes by reducing autophagy.

Ning Y, Li Z, Qiu Z.

J Toxicol Sci. 2015;40(5):637-45. doi: 10.2131/jts.40.637.

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