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Items: 1 to 20 of 96

1.

Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularization.

Husain D, Meyer RD, Mehta M, Pfeifer WM, Chou E, Navruzbekov G, Ahmed E, Rahimi N.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6803-9. doi: 10.1167/iovs.10-5255. Epub 2010 Jun 30.

2.

c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1.

Meyer RD, Husain D, Rahimi N.

Oncogene. 2011 May 12;30(19):2198-206. doi: 10.1038/onc.2010.597. Epub 2011 Jan 17.

3.

A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.

Singh AJ, Meyer RD, Navruzbekov G, Shelke R, Duan L, Band H, Leeman SE, Rahimi N.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5413-8. Epub 2007 Mar 19.

4.

A role for protein ubiquitination in VEGFR-2 signalling and angiogenesis.

Rahimi N.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1189-92. doi: 10.1042/BST0371189.

PMID:
19909244
5.

Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models.

Jhanji V, Liu H, Law K, Lee VY, Huang SF, Pang CP, Yam GH.

Br J Ophthalmol. 2011 Sep;95(9):1309-15. doi: 10.1136/bjophthalmol-2011-300110. Epub 2011 Jun 30.

PMID:
21719569
6.

Knockout of αA-crystallin inhibits ocular neovascularization.

Xu Q, Bai Y, Huang L, Zhou P, Yu W, Zhao M.

Invest Ophthalmol Vis Sci. 2015 Jan 8;56(2):816-26. doi: 10.1167/iovs.14-14734.

PMID:
25574047
7.

Recruitment and activation of phospholipase Cgamma1 by vascular endothelial growth factor receptor-2 are required for tubulogenesis and differentiation of endothelial cells.

Meyer RD, Latz C, Rahimi N.

J Biol Chem. 2003 May 2;278(18):16347-55. Epub 2003 Feb 21. Erratum in: J Biol Chem. 2005 Jul 8;280(27):25948.

8.

Suppression of choroidal neovascularization by vasohibin-1, a vascular endothelium-derived angiogenic inhibitor.

Wakusawa R, Abe T, Sato H, Sonoda H, Sato M, Mitsuda Y, Takakura T, Fukushima T, Onami H, Nagai N, Ishikawa Y, Nishida K, Sato Y.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3272-80. doi: 10.1167/iovs.10-6295.

PMID:
21345982
9.

Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies.

Li S, Huang L, Sun Y, Bai Y, Yang F, Yu W, Li F, Zhang Q, Wang B, Geng JG, Li X.

Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5210-7. doi: 10.1167/iovs-14-16184.

PMID:
26244297
10.

Anti-angiogenic effect of ALS-L1023, an extract of Melissa officinalis L., on experimental choroidal neovascularization in mice.

Roh YJ, Jee D, Rho CR, Cho WK, Kang S.

Clin Exp Ophthalmol. 2016 Jan-Feb;44(1):43-51. doi: 10.1111/ceo.12583. Epub 2015 Oct 1.

PMID:
26221970
11.

Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.

He S, Ding Y, Zhou J, Krasnoperov V, Zozulya S, Kumar SR, Ryan SJ, Gill PS, Hinton DR.

Invest Ophthalmol Vis Sci. 2005 Dec;46(12):4772-9.

PMID:
16303978
12.

Identification of a novel vascular endothelial growth factor receptor 2 inhibitor and its effect for choroidal neovascularization in vivo.

Takahashi H, Tamaki Y, Ishii N, Oikawa N, Mizuguchi E, Francis JH, Inoue Y, Iriyama A, Obata R, Yanagi Y.

Curr Eye Res. 2008 Nov;33(11):1002-10. doi: 10.1080/02713680802492440.

PMID:
19085383
13.

Suppression of experimental choroidal neovascularization utilizing KDR selective receptor tyrosine kinase inhibitor.

Takeda A, Hata Y, Shiose S, Sassa Y, Honda M, Fujisawa K, Sakamoto T, Ishibashi T.

Graefes Arch Clin Exp Ophthalmol. 2003 Sep;241(9):765-72. Epub 2003 Aug 23.

PMID:
12937991
14.

Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.

Reddi AL, Ying G, Duan L, Chen G, Dimri M, Douillard P, Druker BJ, Naramura M, Band V, Band H.

J Biol Chem. 2007 Oct 5;282(40):29336-47. Epub 2007 Jul 9.

15.

Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system.

Hara C, Kasai A, Gomi F, Satooka T, Sakimoto S, Nakai K, Yoshioka Y, Yamamuro A, Maeda S, Nishida K.

Invest Ophthalmol Vis Sci. 2013 Jun 21;54(6):4321-9. doi: 10.1167/iovs.13-11611.

PMID:
23722395
16.

Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization.

Murata T, He S, Hangai M, Ishibashi T, Xi XP, Kim S, Hsueh WA, Ryan SJ, Law RE, Hinton DR.

Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2309-17.

PMID:
10892878
18.

Semaphorin 3A blocks the formation of pathologic choroidal neovascularization induced by transforming growth factor beta.

Bai Y, Liang S, Yu W, Zhao M, Huang L, Zhao M, Li X.

Mol Vis. 2014 Sep 19;20:1258-70. eCollection 2014.

19.

EGFR-PLCgamma1 signaling mediates high glucose-induced PKCbeta1-Akt activation and collagen I upregulation in mesangial cells.

Wu D, Peng F, Zhang B, Ingram AJ, Kelly DJ, Gilbert RE, Gao B, Kumar S, Krepinsky JC.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F822-34. doi: 10.1152/ajprenal.00054.2009. Epub 2009 Jul 15.

20.

Disruption of phospholipase Cgamma1 signalling attenuates cardiac tumor necrosis factor-alpha expression and improves myocardial function during endotoxemia.

Peng T, Shen E, Fan J, Zhang Y, Arnold JM, Feng Q.

Cardiovasc Res. 2008 Apr 1;78(1):90-7. Epub 2007 Dec 12.

PMID:
18079103

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