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Items: 1 to 20 of 89

1.

CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model.

Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P.

Br J Pharmacol. 2010 Jun;160(3):657-68. doi: 10.1111/j.1476-5381.2010.00769.x.

2.

Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.

Rajesh M, Mukhopadhyay P, Haskó G, Liaudet L, Mackie K, Pacher P.

Br J Pharmacol. 2010 Jun;160(3):688-700. doi: 10.1111/j.1476-5381.2010.00712.x.

3.

Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.

Mukhopadhyay P, Rajesh M, Pan H, Patel V, Mukhopadhyay B, Bátkai S, Gao B, Haskó G, Pacher P.

Free Radic Biol Med. 2010 Feb 1;48(3):457-67. doi: 10.1016/j.freeradbiomed.2009.11.022. Epub 2009 Dec 4.

4.

CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.

Mukhopadhyay P, Rajesh M, Bátkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Haskó G, Pacher P.

Cardiovasc Res. 2010 Mar 1;85(4):773-84. doi: 10.1093/cvr/cvp369. Epub 2009 Nov 26.

5.

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy.

Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P.

Diabetes. 2012 Mar;61(3):716-27. doi: 10.2337/db11-0477. Epub 2012 Feb 7.

6.

Cannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death.

Pan H, Mukhopadhyay P, Rajesh M, Patel V, Mukhopadhyay B, Gao B, Haskó G, Pacher P.

J Pharmacol Exp Ther. 2009 Mar;328(3):708-14. doi: 10.1124/jpet.108.147181. Epub 2008 Dec 12.

7.

Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.

El-Remessy AB, Rajesh M, Mukhopadhyay P, Horváth B, Patel V, Al-Gayyar MM, Pillai BA, Pacher P.

Diabetologia. 2011 Jun;54(6):1567-78. doi: 10.1007/s00125-011-2061-4. Epub 2011 Mar 4.

8.

Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells.

McCollum L, Howlett AC, Mukhopadhyay S.

J Pharmacol Exp Ther. 2007 Jun;321(3):930-7. Epub 2007 Mar 22.

9.

A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells.

Chiba T, Ueno S, Obara Y, Nakahata N.

J Pharm Pharmacol. 2011 May;63(5):636-47. doi: 10.1111/j.2042-7158.2011.01250.x. Epub 2011 Mar 28.

PMID:
21492165
10.

Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor.

Pucci M, Pasquariello N, Battista N, Di Tommaso M, Rapino C, Fezza F, Zuccolo M, Jourdain R, Finazzi Agrò A, Breton L, Maccarrone M.

J Biol Chem. 2012 May 4;287(19):15466-78. doi: 10.1074/jbc.M111.314880. Epub 2012 Mar 19.

11.

Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice.

Dubreucq S, Matias I, Cardinal P, Häring M, Lutz B, Marsicano G, Chaouloff F.

Neuropsychopharmacology. 2012 Jul;37(8):1885-900. doi: 10.1038/npp.2012.36. Epub 2012 Mar 21.

12.
13.

Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis.

Domitrović R, Cvijanović O, Pernjak-Pugel E, Skoda M, Mikelić L, Crnčević-Orlić Z.

Food Chem Toxicol. 2013 Dec;62:397-406. doi: 10.1016/j.fct.2013.09.003. Epub 2013 Sep 8.

PMID:
24025684
14.

Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.

Bátkai S, Rajesh M, Mukhopadhyay P, Haskó G, Liaudet L, Cravatt BF, Csiszár A, Ungvári Z, Pacher P.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H909-18. Epub 2007 Apr 13.

15.

Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor.

Schulte K, Steingrüber N, Jergas B, Redmer A, Kurz CM, Buchalla R, Lutz B, Zimmer A, Schlicker E.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Apr;385(4):385-96. doi: 10.1007/s00210-011-0717-8. Epub 2012 Jan 4.

PMID:
22215206
16.
17.

The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization.

Thiemann G, van der Stelt M, Petrosino S, Molleman A, Di Marzo V, Hasenöhrl RU.

Behav Brain Res. 2008 Mar 5;187(2):289-96. Epub 2007 Sep 25.

PMID:
17988751
18.

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.

Mukhopadhyay P, Horváth B, Kechrid M, Tanchian G, Rajesh M, Naura AS, Boulares AH, Pacher P.

Free Radic Biol Med. 2011 Nov 1;51(9):1774-88. doi: 10.1016/j.freeradbiomed.2011.08.006. Epub 2011 Aug 17.

19.

Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.

Lerner TN, Horne EA, Stella N, Kreitzer AC.

J Neurosci. 2010 Feb 10;30(6):2160-4. doi: 10.1523/JNEUROSCI.5844-09.2010.

20.

Attenuation of allergic contact dermatitis through the endocannabinoid system.

Karsak M, Gaffal E, Date R, Wang-Eckhardt L, Rehnelt J, Petrosino S, Starowicz K, Steuder R, Schlicker E, Cravatt B, Mechoulam R, Buettner R, Werner S, Di Marzo V, Tüting T, Zimmer A.

Science. 2007 Jun 8;316(5830):1494-7.

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