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Items: 1 to 20 of 114

1.

Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells.

Kuehn HS, Rådinger M, Brown JM, Ali K, Vanhaesebroeck B, Beaven MA, Metcalfe DD, Gilfillan AM.

J Cell Sci. 2010 Aug 1;123(Pt 15):2576-85. doi: 10.1242/jcs.071043.

2.

Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit.

Iwaki S, Tkaczyk C, Satterthwaite AB, Halcomb K, Beaven MA, Metcalfe DD, Gilfillan AM.

J Biol Chem. 2005 Dec 2;280(48):40261-70.

3.

Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.

Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, Kawakami T.

J Immunol. 2000 Aug 1;165(3):1210-9.

4.

Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.

Smrž D, Bandara G, Beaven MA, Metcalfe DD, Gilfillan AM.

Eur J Immunol. 2013 Jul;43(7):1873-82. doi: 10.1002/eji.201243214.

5.

Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses.

Iyer AS, Morales JL, Huang W, Ojo F, Ning G, Wills E, Baines JD, August A.

J Biol Chem. 2011 Mar 18;286(11):9503-13. doi: 10.1074/jbc.M110.165613.

6.

TRPM4 regulates migration of mast cells in mice.

Shimizu T, Owsianik G, Freichel M, Flockerzi V, Nilius B, Vennekens R.

Cell Calcium. 2009 Mar;45(3):226-32. doi: 10.1016/j.ceca.2008.10.005.

PMID:
19046767
7.
8.

Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release.

Kuehn HS, Beaven MA, Ma HT, Kim MS, Metcalfe DD, Gilfillan AM.

Cell Signal. 2008 Apr;20(4):625-36. doi: 10.1016/j.cellsig.2007.11.016.

9.

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release.

Kuehn HS, Jung MY, Beaven MA, Metcalfe DD, Gilfillan AM.

J Biol Chem. 2011 Jan 7;286(1):391-402. doi: 10.1074/jbc.M110.164772.

10.

Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells.

Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS.

Int Immunol. 2003 Dec;15(12):1431-40.

11.

Stem cell factor has a suppressive activity to IgE-mediated chemotaxis of mast cells.

Sawada J, Shimizu S, Tamatani T, Kanegasaki S, Saito H, Tanaka A, Kambe N, Nakahata T, Matsuda H.

J Immunol. 2005 Mar 15;174(6):3626-32.

12.

SHP2 phosphatase promotes mast cell chemotaxis toward stem cell factor via enhancing activation of the Lyn/Vav/Rac signaling axis.

Sharma N, Everingham S, Ramdas B, Kapur R, Craig AW.

J Immunol. 2014 May 15;192(10):4859-66. doi: 10.4049/jimmunol.1301155.

13.

Tyrosine kinase-deficient Wv c-kit induces mast cell adhesion and chemotaxis.

Dastych J, Taub D, Hardison MC, Metcalfe DD.

Am J Physiol. 1998 Nov;275(5 Pt 1):C1291-9.

14.

A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses.

Smrž D, Bandara G, Zhang S, Mock BA, Beaven MA, Metcalfe DD, Gilfillan AM.

J Immunol Methods. 2013 Apr 30;390(1-2):52-62. doi: 10.1016/j.jim.2013.01.008.

15.

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.

Hata D, Kawakami Y, Inagaki N, Lantz CS, Kitamura T, Khan WN, Maeda-Yamamoto M, Miura T, Han W, Hartman SE, Yao L, Nagai H, Goldfeld AE, Alt FW, Galli SJ, Witte ON, Kawakami T.

J Exp Med. 1998 Apr 20;187(8):1235-47.

16.

SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration.

Sivalenka RR, Jessberger R.

Mol Cell Biol. 2004 Dec;24(23):10277-88.

17.

Defective degranulation and calcium mobilization of bone-marrow derived mast cells from Xid and Btk-deficient mice.

Setoguchi R, Kinashi T, Sagara H, Hirosawa K, Takatsu K.

Immunol Lett. 1998 Dec;64(2-3):109-18.

PMID:
9870661
18.

Citreorosein inhibits degranulation and leukotriene C₄ generation through suppression of Syk pathway in mast cells.

Lu Y, Li Y, Jahng Y, Son JK, Chang HW.

Mol Cell Biochem. 2012 Jun;365(1-2):333-41. doi: 10.1007/s11010-012-1273-3.

PMID:
22395859
19.

LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival.

Yamasaki S, Ishikawa E, Sakuma M, Kanagawa O, Cheng AM, Malissen B, Saito T.

Mol Cell Biol. 2007 Jun;27(12):4406-15.

20.

AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice.

Hwang SL, Li X, Lu Y, Jin Y, Jeong YT, Kim YD, Lee IK, Taketomi Y, Sato H, Cho YS, Murakami M, Chang HW.

J Allergy Clin Immunol. 2013 Sep;132(3):729-736.e12. doi: 10.1016/j.jaci.2013.02.018.

PMID:
23587332
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