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IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery.

Ndhlovu LC, Sinclair E, Epling L, Tan QX, Ho T, Jha AR, Eccles-James I, Tincati C, Levy JA, Nixon DF, Hecht FM, Barbour JD.

J Clin Immunol. 2010 Sep;30(5):681-92. doi: 10.1007/s10875-010-9432-3. Epub 2010 Jun 23.


Antiretroviral therapy-induced dominant interleukin-2 HIV-1 Gag CD4+ T cell response: evidence of functional recovery of HIV-1-specific CD4+ T cells.

Tsalimalma K, Kordossis T, Choremi-Papadopoulou E.

Scand J Immunol. 2011 Mar;73(3):256-65. doi: 10.1111/j.1365-3083.2010.02502.x.


Impaired Upregulation of the Costimulatory Molecules, CD27 and CD28, on CD4+ T Cells from HIV Patients Receiving ART Is Associated with Poor Proliferative Responses.

Tanaskovic S, Price P, French MA, Fernandez S.

AIDS Res Hum Retroviruses. 2017 Feb;33(2):101-109. doi: 10.1089/AID.2015.0327. Epub 2016 Nov 14.


Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART.

DaFonseca S, Niessl J, Pouvreau S, Wacleche VS, Gosselin A, Cleret-Buhot A, Bernard N, Tremblay C, Jenabian MA, Routy JP, Ancuta P.

Retrovirology. 2015 Apr 30;12:38. doi: 10.1186/s12977-015-0164-6.


Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection.

Boaz MJ, Waters A, Murad S, Easterbrook PJ, Vyakarnam A.

J Immunol. 2002 Dec 1;169(11):6376-85.


Regulation of Gag- and Env-Specific CD8+ T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy.

Prebensen C, Lind A, Dyrhol-Riise AM, Kvale D.

PLoS One. 2016 Apr 29;11(4):e0153849. doi: 10.1371/journal.pone.0153849. eCollection 2016.


mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients.

Van Gulck E, Vlieghe E, Vekemans M, Van Tendeloo VF, Van De Velde A, Smits E, Anguille S, Cools N, Goossens H, Mertens L, De Haes W, Wong J, Florence E, Vanham G, Berneman ZN.

AIDS. 2012 Feb 20;26(4):F1-12. doi: 10.1097/QAD.0b013e32834f33e8.


Simultaneous activation of viral antigen-specific memory CD4+ and CD8+ T-cells using mRNA-electroporated CD40-activated autologous B-cells.

Van den Bosch GA, Van Gulck E, Ponsaerts P, Nijs G, Lenjou M, Apers L, Kint I, Heyndrickx L, Vanham G, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF.

J Immunother. 2006 Sep-Oct;29(5):512-23.


CD8+ T cells in HIV disease exhibit cytokine receptor perturbation and poor T cell receptor activation but are responsive to gamma-chain cytokine-driven proliferation.

Pahwa R, McCloskey TW, Aroniadis OC, Strbo N, Krishnan S, Pahwa S.

J Infect Dis. 2006 Mar 15;193(6):879-87. Epub 2006 Feb 9.


HIV-1-infected children on HAART: immunologic features of three different levels of viral suppression.

Zaccarelli-Filho CA, Ono E, Machado DM, Brunialti M, Succi RC, Salomão R, Kallás EG, de Moraes-Pinto MI.

Cytometry B Clin Cytom. 2007 Jan 15;72(1):14-21.


Dominant ex vivo cross-stimulation of CD8+ T-cells with whole soluble gag protein in HIV-infected subjects.

Tavernier A, Jennes W, Fransen K, De Roo A, Kestens L.

J Acquir Immune Defic Syndr. 2006 Apr 15;41(5):548-56.


Increased levels of regulatory T cells (Tregs) in human immunodeficiency virus-infected patients after 5 years of highly active anti-retroviral therapy may be due to increased thymic production of naive Tregs.

Kolte L, Gaardbo JC, Skogstrand K, Ryder LP, Ersbøll AK, Nielsen SD.

Clin Exp Immunol. 2009 Jan;155(1):44-52. doi: 10.1111/j.1365-2249.2008.03803.x. Epub 2008 Nov 6.


Interleukin-2 therapy restores CD8 cell non-cytotoxic anti-HIV responses in primary infection subjects receiving HAART.

Martinez-Mariño B, Shiboski S, Hecht FM, Kahn JO, Levy JA.

AIDS. 2004 Oct 21;18(15):1991-9.


Immunological benefits of antiretroviral therapy in very early stages of asymptomatic chronic HIV-1 infection.

Plana M, García F, Gallart T, Tortajada C, Soriano A, Palou E, Maleno MJ, Barceló JJ, Vidal C, Cruceta A, Miró JM, Gatell JM.

AIDS. 2000 Sep 8;14(13):1921-33.


Replication-defective canarypox (ALVAC) vectors effectively activate anti-human immunodeficiency virus-1 cytotoxic T lymphocytes present in infected patients: implications for antigen-specific immunotherapy.

Ferrari G, Berend C, Ottinger J, Dodge R, Bartlett J, Toso J, Moody D, Tartaglia J, Cox WI, Paoletti E, Weinhold KJ.

Blood. 1997 Sep 15;90(6):2406-16.


Analysis of the effect of highly active antiretroviral therapy during acute HIV-1 infection on HIV-specific CD4 T cell functions.

Jansen CA, De Cuyper IM, Steingrover R, Jurriaans S, Sankatsing SU, Prins JM, Lange JM, van Baarle D, Miedema F.

AIDS. 2005 Jul 22;19(11):1145-54.


IL-2 therapy and thymic production of naive CD4 T cells in HIV-infected patients with severe CD4 lymphopenia.

Carcelain G, Saint-Mézard P, Altes HK, Tubiana R, Grenot P, Rabian C, de Boer R, Costagliola D, Katlama C, Debré P, Autran B.

AIDS. 2003 Apr 11;17(6):841-50.


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