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Items: 1 to 20 of 141

1.

RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation.

D'Orso I, Frankel AD.

Nat Struct Mol Biol. 2010 Jul;17(7):815-21. doi: 10.1038/nsmb.1827. Epub 2010 Jun 20.

2.

Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA.

D'Orso I, Jang GM, Pastuszak AW, Faust TB, Quezada E, Booth DS, Frankel AD.

Mol Cell Biol. 2012 Dec;32(23):4780-93. doi: 10.1128/MCB.00206-12. Epub 2012 Sep 24.

3.

Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat.

Muniz L, Egloff S, Ughy B, Jády BE, Kiss T.

PLoS Pathog. 2010 Oct 14;6(10):e1001152. doi: 10.1371/journal.ppat.1001152.

4.

Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.

McNamara RP, McCann JL, Gudipaty SA, D'Orso I.

Cell Rep. 2013 Dec 12;5(5):1256-68. doi: 10.1016/j.celrep.2013.11.003. Epub 2013 Dec 5.

5.

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.

Sobhian B, Laguette N, Yatim A, Nakamura M, Levy Y, Kiernan R, Benkirane M.

Mol Cell. 2010 May 14;38(3):439-51. doi: 10.1016/j.molcel.2010.04.012.

6.

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

Barboric M, Yik JH, Czudnochowski N, Yang Z, Chen R, Contreras X, Geyer M, Matija Peterlin B, Zhou Q.

Nucleic Acids Res. 2007;35(6):2003-12. Epub 2007 Mar 6.

7.

The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.

Krueger BJ, Varzavand K, Cooper JJ, Price DH.

PLoS One. 2010 Aug 23;5(8):e12335. doi: 10.1371/journal.pone.0012335.

8.

Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion.

Barboric M, Lenasi T.

Nat Struct Mol Biol. 2010 Aug;17(8):928-30. doi: 10.1038/nsmb0810-928.

PMID:
20683478
9.

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

McNamara RP, Reeder JE, McMillan EA, Bacon CW, McCann JL, D'Orso I.

Mol Cell. 2016 Jan 7;61(1):39-53. doi: 10.1016/j.molcel.2015.11.004. Epub 2015 Dec 24.

10.

HMGA1 directly interacts with TAR to modulate basal and Tat-dependent HIV transcription.

Eilebrecht S, Wilhelm E, Benecke BJ, Bell B, Benecke AG.

RNA Biol. 2013 Mar;10(3):436-44. doi: 10.4161/rna.23686. Epub 2013 Feb 7.

11.

HIV-1 transcription is regulated by splicing factor SRSF1.

Paz S, Krainer AR, Caputi M.

Nucleic Acids Res. 2014 Dec 16;42(22):13812-23.

12.

PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.

Gudipaty SA, McNamara RP, Morton EL, D'Orso I.

Mol Cell Biol. 2015 Nov;35(22):3810-28. doi: 10.1128/MCB.00226-15. Epub 2015 Aug 31.

13.

Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.

Bartholomeeusen K, Xiang Y, Fujinaga K, Peterlin BM.

J Biol Chem. 2012 Oct 19;287(43):36609-16. doi: 10.1074/jbc.M112.410746. Epub 2012 Sep 5. Erratum in: J Biol Chem. 2013 Apr 26;288(17):12214.

14.

New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).

He N, Zhou Q.

J Neuroimmune Pharmacol. 2011 Jun;6(2):260-8. doi: 10.1007/s11481-011-9267-6. Epub 2011 Mar 1. Review.

15.

Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.

Sedore SC, Byers SA, Biglione S, Price JP, Maury WJ, Price DH.

Nucleic Acids Res. 2007;35(13):4347-58. Epub 2007 Jun 18.

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18.

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.

He N, Liu M, Hsu J, Xue Y, Chou S, Burlingame A, Krogan NJ, Alber T, Zhou Q.

Mol Cell. 2010 May 14;38(3):428-38. doi: 10.1016/j.molcel.2010.04.013.

19.

ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter.

Bruce JW, Reddington R, Mathieu E, Bracken M, Young JA, Ahlquist P.

PLoS Pathog. 2013 Oct;9(10):e1003712. doi: 10.1371/journal.ppat.1003712. Epub 2013 Oct 24.

20.

Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.

Liu P, Xiang Y, Fujinaga K, Bartholomeeusen K, Nilson KA, Price DH, Peterlin BM.

J Biol Chem. 2014 Apr 4;289(14):9918-25. doi: 10.1074/jbc.M113.539015. Epub 2014 Feb 10.

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