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Items: 1 to 20 of 79

1.

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.

Gao N, Le Lay J, Qin W, Doliba N, Schug J, Fox AJ, Smirnova O, Matschinsky FM, Kaestner KH.

Mol Endocrinol. 2010 Aug;24(8):1594-604. doi: 10.1210/me.2009-0513. Epub 2010 Jun 9.

2.

Foxa1 and Foxa2 regulate α-cell differentiation, glucagon biosynthesis, and secretion.

Heddad Masson M, Poisson C, Guérardel A, Mamin A, Philippe J, Gosmain Y.

Endocrinology. 2014 Oct;155(10):3781-92. doi: 10.1210/en.2013-1843. Epub 2014 Jul 24.

PMID:
25057789
3.

Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.

Ferri AL, Lin W, Mavromatakis YE, Wang JC, Sasaki H, Whitsett JA, Ang SL.

Development. 2007 Aug;134(15):2761-9. Epub 2007 Jun 27.

4.

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells.

Gao N, White P, Doliba N, Golson ML, Matschinsky FM, Kaestner KH.

Cell Metab. 2007 Oct;6(4):267-79.

5.

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.

Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL.

Dev Biol. 2009 Sep 15;333(2):386-96. doi: 10.1016/j.ydbio.2009.07.006. Epub 2009 Jul 14.

6.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.

7.

Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.

Ye DZ, Kaestner KH.

Gastroenterology. 2009 Dec;137(6):2052-62. doi: 10.1053/j.gastro.2009.08.059. Epub 2009 Sep 6.

8.

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.

Jia S, Ivanov A, Blasevic D, Müller T, Purfürst B, Sun W, Chen W, Poy MN, Rajewsky N, Birchmeier C.

EMBO J. 2015 May 12;34(10):1417-33. doi: 10.15252/embj.201490819. Epub 2015 Mar 31.

9.

Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.

Pristerà A, Lin W, Kaufmann AK, Brimblecombe KR, Threlfell S, Dodson PD, Magill PJ, Fernandes C, Cragg SJ, Ang SL.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4929-38. doi: 10.1073/pnas.1503911112. Epub 2015 Aug 17.

10.

Expression and role of Foxa proteins in prostate cancer.

Mirosevich J, Gao N, Gupta A, Shappell SB, Jove R, Matusik RJ.

Prostate. 2006 Jul 1;66(10):1013-28.

PMID:
16001449
11.

Foxa1 and Foxa2 are required for formation of the intervertebral discs.

Maier JA, Lo Y, Harfe BD.

PLoS One. 2013;8(1):e55528. doi: 10.1371/journal.pone.0055528. Epub 2013 Jan 31.

12.

Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.

Wan H, Dingle S, Xu Y, Besnard V, Kaestner KH, Ang SL, Wert S, Stahlman MT, Whitsett JA.

J Biol Chem. 2005 Apr 8;280(14):13809-16. Epub 2005 Jan 24.

13.

A novel function of Onecut1 protein as a negative regulator of MafA gene expression.

Yamamoto K, Matsuoka TA, Kawashima S, Takebe S, Kubo F, Miyatsuka T, Kaneto H, Shimomura I.

J Biol Chem. 2013 Jul 26;288(30):21648-58. doi: 10.1074/jbc.M113.481424. Epub 2013 Jun 17. Erratum in: J Biol Chem. 2013 Oct 25;288(43):31298. Kubo, Noriyo [corrected to Kubo, Fumiyo].

14.

The Foxa family of transcription factors in development and metabolism.

Friedman JR, Kaestner KH.

Cell Mol Life Sci. 2006 Oct;63(19-20):2317-28. Review.

PMID:
16909212
15.

Conditional Tissue-Specific Foxa2 Ablation in Mouse Pancreas Causes Hyperinsulinemic Hypoglycemia.

Wu Z, Fei A, Liu Y, Pan S.

Am J Ther. 2016 Nov/Dec;23(6):e1442-e1448.

PMID:
26882312
16.

Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release.

Wang H, Gauthier BR, Hagenfeldt-Johansson KA, Iezzi M, Wollheim CB.

J Biol Chem. 2002 May 17;277(20):17564-70. Epub 2002 Mar 1.

17.

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.

Besnard V, Wert SE, Hull WM, Whitsett JA.

Gene Expr Patterns. 2004 Dec;5(2):193-208.

PMID:
15567715
18.

Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.

Bochkis IM, Schug J, Ye DZ, Kurinna S, Stratton SA, Barton MC, Kaestner KH.

PLoS Genet. 2012;8(6):e1002770. doi: 10.1371/journal.pgen.1002770. Epub 2012 Jun 21.

19.

The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH.

Wang R, Shi Y, Chen L, Jiang Y, Mao C, Yan B, Liu S, Shan B, Tao Y, Wang X.

Sci Rep. 2015 Dec 11;5:17826. doi: 10.1038/srep17826.

20.

Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier.

Menga A, Infantino V, Iacobazzi F, Convertini P, Palmieri F, Iacobazzi V.

Eur Neuropsychopharmacol. 2013 Aug;23(8):978-87. doi: 10.1016/j.euroneuro.2012.08.015. Epub 2012 Sep 7.

PMID:
22959654

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