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Items: 1 to 20 of 121

1.

Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models.

Sei Y, Li Z, Song J, Ren-Patterson R, Tunbridge EM, Iizuka Y, Inoue M, Alfonso BT, Beltaifa S, Nakai Y, Kolachana BS, Chen J, Weinberger DR.

PLoS One. 2010 May 24;5(5):e10789. doi: 10.1371/journal.pone.0010789.

2.

Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms.

Sei Y, Ren-Patterson R, Li Z, Tunbridge EM, Egan MF, Kolachana BS, Weinberger DR.

Mol Psychiatry. 2007 Oct;12(10):946-57. Epub 2007 Apr 17.

PMID:
17440436
4.

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.

Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR.

Arch Gen Psychiatry. 2010 Oct;67(10):991-1001. doi: 10.1001/archgenpsychiatry.2010.117.

5.

Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications.

Tan HY, Chen AG, Chen Q, Browne LB, Verchinski B, Kolachana B, Zhang F, Apud J, Callicott JH, Mattay VS, Weinberger DR.

Mol Psychiatry. 2012 Oct;17(10):1007-16. doi: 10.1038/mp.2011.91. Epub 2011 Jul 26.

6.

Association between catechol-O-methyltrasferase Val108/158Met genotype and prefrontal hemodynamic response in schizophrenia.

Takizawa R, Tochigi M, Kawakubo Y, Marumo K, Sasaki T, Fukuda M, Kasai K.

PLoS One. 2009;4(5):e5495. doi: 10.1371/journal.pone.0005495. Epub 2009 May 8.

7.

Interaction between catechol-O-methyltransferase (COMT) Val108/158Met and brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in age at onset and clinical symptoms in schizophrenia.

Numata S, Ueno S, Iga J, Yamauchi K, Hongwei S, Kinouchi S, Shibuya-Tayoshi S, Tayoshi S, Aki H, Sumitani S, Itakura M, Ohmori T.

J Neural Transm (Vienna). 2007 Feb;114(2):255-9. Epub 2006 Aug 8.

PMID:
16897602
9.

COMT val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia.

Woodward ND, Jayathilake K, Meltzer HY.

Schizophr Res. 2007 Feb;90(1-3):86-96. Epub 2006 Nov 22.

PMID:
17123785
10.

RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity.

Lipska BK, Mitkus S, Caruso M, Hyde TM, Chen J, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE.

Hum Mol Genet. 2006 Sep 15;15(18):2804-12. Epub 2006 Aug 11.

PMID:
16905560
11.

The relationship between the val158met catechol-O-methyltransferase (COMT) polymorphism and irritable bowel syndrome.

Karling P, Danielsson Å, Wikgren M, Söderström I, Del-Favero J, Adolfsson R, Norrback KF.

PLoS One. 2011 Mar 18;6(3):e18035. doi: 10.1371/journal.pone.0018035.

12.

Association between the catechol O-methyltransferase Val108/158Met polymorphism and alexithymia.

Ham BJ, Lee MS, Lee YM, Kim MK, Choi MJ, Oh KS, Jung HY, Lyoo IK, Choi IG.

Neuropsychobiology. 2005;52(3):151-4.

PMID:
16127282
13.

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.

Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, Egan MF, Kleinman JE, Weinberger DR.

Am J Hum Genet. 2004 Nov;75(5):807-21. Epub 2004 Sep 27. Erratum in: Am J Hum Genet. 2005 Jun;76(6):1089.

14.

Catechol-O-methyltransferase gene Val108/158Met polymorphism, and susceptibility to schizophrenia: association is more significant in women.

Sazci A, Ergul E, Kucukali I, Kilic G, Kaya G, Kara I.

Brain Res Mol Brain Res. 2004 Dec 6;132(1):51-6.

PMID:
15548428
15.

Distribution of the Val108/158Met polymorphism of the COMT gene in healthy Mexican population.

González-Castro TB, Tovilla-Zárate C, Juárez-Rojop I, Pool García S, Genis A, Nicolini H, López Narváez L.

Gene. 2013 Sep 10;526(2):454-8. doi: 10.1016/j.gene.2013.05.068. Epub 2013 Jun 14.

16.

MTHFR 677C --> T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val --> Met.

Roffman JL, Gollub RL, Calhoun VD, Wassink TH, Weiss AP, Ho BC, White T, Clark VP, Fries J, Andreasen NC, Goff DC, Manoach DS.

Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17573-8. doi: 10.1073/pnas.0803727105. Epub 2008 Nov 6.

17.

Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling.

Ieguchi K, Fujita M, Ma Z, Davari P, Taniguchi Y, Sekiguchi K, Wang B, Takada YK, Takada Y.

J Biol Chem. 2010 Oct 8;285(41):31388-98. doi: 10.1074/jbc.M110.113878. Epub 2010 Aug 3.

18.

Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia.

Roffman JL, Weiss AP, Deckersbach T, Freudenreich O, Henderson DC, Wong DH, Halsted CH, Goff DC.

Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):990-5. doi: 10.1002/ajmg.b.30684.

PMID:
18186041
19.

Relationship between the catechol-O-methyl transferase Val108/158Met genotype and brain volume in treatment-naive major depressive disorder: Voxel-based morphometry analysis.

Watanabe K, Kakeda S, Yoshimura R, Abe O, Ide S, Hayashi K, Katsuki A, Umene-Nakano W, Watanabe R, Nakamura J, Korogi Y.

Psychiatry Res. 2015 Sep 30;233(3):481-7. doi: 10.1016/j.pscychresns.2015.07.024. Epub 2015 Jul 31.

PMID:
26253436
20.

Catechol-O-methyltransferase: effects of the val108met polymorphism on protein turnover in human cells.

Doyle AE, Yager JD.

Biochim Biophys Acta. 2008 Jan;1780(1):27-33. Epub 2007 Oct 16.

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