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Items: 1 to 20 of 164

1.

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice.

Amar MJ, D'Souza W, Turner S, Demosky S, Sviridov D, Stonik J, Luchoomun J, Voogt J, Hellerstein M, Sviridov D, Remaley AT.

J Pharmacol Exp Ther. 2010 Aug;334(2):634-41. doi: 10.1124/jpet.110.167890. Epub 2010 May 19.

2.

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR.

J Clin Invest. 2007 Dec;117(12):3900-8.

3.

The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice.

Ying R, Yuan Y, Qin YF, Tian D, Feng L, Guo ZG, Sun YX, Li MX.

Lipids Health Dis. 2013 Dec 8;12:180. doi: 10.1186/1476-511X-12-180.

4.

Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet.

Song G, Liu J, Zhao Z, Yu Y, Tian H, Yao S, Li G, Qin S.

Lipids Health Dis. 2011 Jan 18;10:8. doi: 10.1186/1476-511X-10-8.

5.

The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties.

Schwendeman A, Sviridov DO, Yuan W, Guo Y, Morin EE, Yuan Y, Stonik J, Freeman L, Ossoli A, Thacker S, Killion S, Pryor M, Chen YE, Turner S, Remaley AT.

J Lipid Res. 2015 Sep;56(9):1727-37. doi: 10.1194/jlr.M060285. Epub 2015 Jun 27.

6.

Hydrophobic amino acids in the hinge region of the 5A apolipoprotein mimetic peptide are essential for promoting cholesterol efflux by the ABCA1 transporter.

Sviridov DO, Andrianov AM, Anishchenko IV, Stonik JA, Amar MJ, Turner S, Remaley AT.

J Pharmacol Exp Ther. 2013 Jan;344(1):50-8. doi: 10.1124/jpet.112.198143. Epub 2012 Oct 5.

7.

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.

Joyce CW, Amar MJ, Lambert G, Vaisman BL, Paigen B, Najib-Fruchart J, Hoyt RF Jr, Neufeld ED, Remaley AT, Fredrickson DS, Brewer HB Jr, Santamarina-Fojo S.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):407-12. Epub 2001 Dec 18.

8.

Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.

Lammers B, Out R, Hildebrand RB, Quinn CM, Williamson D, Hoekstra M, Meurs I, Van Berkel TJ, Jessup W, Van Eck M.

Atherosclerosis. 2009 Aug;205(2):420-6. doi: 10.1016/j.atherosclerosis.2009.01.017. Epub 2009 Jan 23.

PMID:
19217108
9.

The effect of T0901317 on ATP-binding cassette transporter A1 and Niemann-Pick type C1 in apoE-/- mice.

Dai XY, Ou X, Hao XR, Cao DL, Tang YL, Hu YW, Li XX, Tang CK.

J Cardiovasc Pharmacol. 2008 May;51(5):467-75. doi: 10.1097/FJC.0b013e31816a5be3.

PMID:
18437096
10.

Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages.

Wu C, Luan H, Zhang X, Wang S, Zhang X, Sun X, Guo P.

PLoS One. 2014 Sep 4;9(9):e95452. doi: 10.1371/journal.pone.0095452. eCollection 2014.

11.

CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages.

Bujold K, Rhainds D, Jossart C, Febbraio M, Marleau S, Ong H.

Cardiovasc Res. 2009 Aug 1;83(3):457-64. doi: 10.1093/cvr/cvp118. Epub 2009 Apr 17.

PMID:
19377069
12.

MicroRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE-/- mice.

Horie T, Baba O, Kuwabara Y, Chujo Y, Watanabe S, Kinoshita M, Horiguchi M, Nakamura T, Chonabayashi K, Hishizawa M, Hasegawa K, Kume N, Yokode M, Kita T, Kimura T, Ono K.

J Am Heart Assoc. 2012 Dec;1(6):e003376. doi: 10.1161/JAHA.112.003376. Epub 2012 Dec 19.

13.

Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice.

Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Wagner AC, Frank JS, Datta G, Garber D, Fogelman AM.

Circulation. 2004 Jun 29;109(25):3215-20. Epub 2004 Jun 14.

14.

Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.

Favari E, Calabresi L, Adorni MP, Jessup W, Simonelli S, Franceschini G, Bernini F.

Biochemistry. 2009 Nov 24;48(46):11067-74. doi: 10.1021/bi901564g.

PMID:
19839639
15.

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.

Cuchel M, Lund-Katz S, de la Llera-Moya M, Millar JS, Chang D, Fuki I, Rothblat GH, Phillips MC, Rader DJ.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):526-32. doi: 10.1161/ATVBAHA.109.196105. Epub 2009 Dec 17.

16.

EP 80317, a ligand of the CD36 scavenger receptor, protects apolipoprotein E-deficient mice from developing atherosclerotic lesions.

Marleau S, Harb D, Bujold K, Avallone R, Iken K, Wang Y, Demers A, Sirois MG, Febbraio M, Silverstein RL, Tremblay A, Ong H.

FASEB J. 2005 Nov;19(13):1869-71. Epub 2005 Aug 25.

PMID:
16123174
17.

Augmented atherogenesis in LDL receptor deficient mice lacking both macrophage ABCA1 and ApoE.

Lammers B, Zhao Y, Hoekstra M, Hildebrand RB, Ye D, Meurs I, Van Berkel TJ, Van Eck M.

PLoS One. 2011;6(10):e26095. doi: 10.1371/journal.pone.0026095. Epub 2011 Oct 11.

18.

Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis.

Saeed O, Otsuka F, Polavarapu R, Karmali V, Weiss D, Davis T, Rostad B, Pachura K, Adams L, Elliott J, Taylor WR, Narula J, Kolodgie F, Virmani R, Hong CC, Finn AV.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):299-307. doi: 10.1161/ATVBAHA.111.240101. Epub 2011 Nov 17.

19.

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.

Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR.

J Lipid Res. 2008 Jan;49(1):107-14. Epub 2007 Oct 24.

20.

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.

Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR.

J Clin Invest. 2011 Oct;121(10):4138-49. doi: 10.1172/JCI57559.

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