Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 78

1.

Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1.

Chong HK, Infante AM, Seo YK, Jeon TI, Zhang Y, Edwards PA, Xie X, Osborne TF.

Nucleic Acids Res. 2010 Oct;38(18):6007-17. doi: 10.1093/nar/gkq397.

2.

Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR.

Chong HK, Biesinger J, Seo YK, Xie X, Osborne TF.

BMC Genomics. 2012 Feb 1;13:51. doi: 10.1186/1471-2164-13-51.

3.

Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice.

Lee J, Seok S, Yu P, Kim K, Smith Z, Rivas-Astroza M, Zhong S, Kemper JK.

Hepatology. 2012 Jul;56(1):108-17. doi: 10.1002/hep.25609.

4.

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

Thomas AM, Hart SN, Kong B, Fang J, Zhong XB, Guo GL.

Hepatology. 2010 Apr;51(4):1410-9. doi: 10.1002/hep.23450. Erratum in: Hepatology. 2010 Jul;52(1):402.

5.

Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1.

Hoeke MO, Heegsma J, Hoekstra M, Moshage H, Faber KN.

PLoS One. 2014 Feb 3;9(2):e88011. doi: 10.1371/journal.pone.0088011.

6.

Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale.

Thomas AM, Hart SN, Li G, Lu H, Fang Y, Fang J, Zhong XB, Guo GL.

Pharm Res. 2013 Sep;30(9):2188-98. doi: 10.1007/s11095-013-1006-7.

7.

SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes.

Balasubramaniyan N, Luo Y, Sun AQ, Suchy FJ.

J Biol Chem. 2013 May 10;288(19):13850-62. doi: 10.1074/jbc.M112.443937.

8.

Farnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner.

Li G, Thomas AM, Hart SN, Zhong X, Wu D, Guo GL.

Mol Endocrinol. 2010 Jul;24(7):1404-12. doi: 10.1210/me.2010-0014.

9.

Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase.

Matsukuma KE, Bennett MK, Huang J, Wang L, Gil G, Osborne TF.

J Lipid Res. 2006 Dec;47(12):2754-61.

10.

Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis.

Shin DJ, Joshi P, Hong SH, Mosure K, Shin DG, Osborne TF.

Nucleic Acids Res. 2012 Dec;40(22):11499-509. doi: 10.1093/nar/gks932.

11.

The hepatic orosomucoid/α1-acid glycoprotein gene cluster is regulated by the nuclear bile acid receptor FXR.

Porez G, Gross B, Prawitt J, Gheeraert C, Berrabah W, Alexandre J, Staels B, Lefebvre P.

Endocrinology. 2013 Oct;154(10):3690-701. doi: 10.1210/en.2013-1263.

PMID:
23861371
12.

Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes.

Zhan L, Liu HX, Fang Y, Kong B, He Y, Zhong XB, Fang J, Wan YJ, Guo GL.

PLoS One. 2014 Sep 8;9(9):e105930. doi: 10.1371/journal.pone.0105930.

13.

Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes.

Caron S, Huaman Samanez C, Dehondt H, Ploton M, Briand O, Lien F, Dorchies E, Dumont J, Postic C, Cariou B, Lefebvre P, Staels B.

Mol Cell Biol. 2013 Jun;33(11):2202-11. doi: 10.1128/MCB.01004-12.

14.

Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.

Pineda Torra I, Claudel T, Duval C, Kosykh V, Fruchart JC, Staels B.

Mol Endocrinol. 2003 Feb;17(2):259-72.

PMID:
12554753
15.

Farnesoid X receptor regulates bile acid-amino acid conjugation.

Pircher PC, Kitto JL, Petrowski ML, Tangirala RK, Bischoff ED, Schulman IG, Westin SK.

J Biol Chem. 2003 Jul 25;278(30):27703-11.

16.

The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2.

Tarling EJ, Ahn H, de Aguiar Vallim TQ.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):787-95. doi: 10.1161/ATVBAHA.114.304179.

17.

Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity.

Lee FY, de Aguiar Vallim TQ, Chong HK, Zhang Y, Liu Y, Jones SA, Osborne TF, Edwards PA.

Mol Endocrinol. 2010 Aug;24(8):1626-36. doi: 10.1210/me.2010-0117.

18.

Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells.

Takayama K, Tsutsumi S, Katayama S, Okayama T, Horie-Inoue K, Ikeda K, Urano T, Kawazu C, Hasegawa A, Ikeo K, Gojyobori T, Ouchi Y, Hayashizaki Y, Aburatani H, Inoue S.

Oncogene. 2011 Feb 3;30(5):619-30. doi: 10.1038/onc.2010.436.

PMID:
20890304
19.

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor.

de Aguiar Vallim TQ, Tarling EJ, Kim T, Civelek M, Baldán Á, Esau C, Edwards PA.

Circ Res. 2013 Jun 7;112(12):1602-12. doi: 10.1161/CIRCRESAHA.112.300648.

20.

Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids.

Frankenberg T, Rao A, Chen F, Haywood J, Shneider BL, Dawson PA.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G912-22.

Items per page

Supplemental Content

Support Center