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Items: 1 to 20 of 88


Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo.

Wang X, He L, Wu YI, Hahn KM, Montell DJ.

Nat Cell Biol. 2010 Jun;12(6):591-7. doi: 10.1038/ncb2061.


Spatiotemporal control of small GTPases with light using the LOV domain.

Wu YI, Wang X, He L, Montell D, Hahn KM.

Methods Enzymol. 2011;497:393-407. doi: 10.1016/B978-0-12-385075-1.00016-0.


A genetically encoded photoactivatable Rac controls the motility of living cells.

Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, Hahn KM.

Nature. 2009 Sep 3;461(7260):104-8. doi: 10.1038/nature08241.


Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis.

Zhang L, Luo J, Wan P, Wu J, Laski F, Chen J.

Development. 2011 Feb;138(3):455-64. doi: 10.1242/dev.046870.


GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation.

Fernández-Espartero CH, Ramel D, Farago M, Malartre M, Luque CM, Limanovich S, Katzav S, Emery G, Martín-Bermudo MD.

J Cell Sci. 2013 May 15;126(Pt 10):2285-93. doi: 10.1242/jcs.124438.


Inhibition of Rac activation as a mechanism for negative regulation of actin cytoskeletal reorganization and cell motility by cAMP.

Nagasawa SY, Takuwa N, Sugimoto N, Mabuchi H, Takuwa Y.

Biochem J. 2005 Feb 1;385(Pt 3):737-44.


The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration.

Yip SC, El-Sibai M, Coniglio SJ, Mouneimne G, Eddy RJ, Drees BE, Neilsen PO, Goswami S, Symons M, Condeelis JS, Backer JM.

J Cell Sci. 2007 Sep 1;120(Pt 17):3138-46.


Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

Bosse T, Ehinger J, Czuchra A, Benesch S, Steffen A, Wu X, Schloen K, Niemann HH, Scita G, Stradal TE, Brakebusch C, Rottner K.

Mol Cell Biol. 2007 Oct;27(19):6615-28.


Pak3 regulates apical-basal polarity in migrating border cells during Drosophila oogenesis.

Felix M, Chayengia M, Ghosh R, Sharma A, Prasad M.

Development. 2015 Nov 1;142(21):3692-703. doi: 10.1242/dev.125682.


Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX.

Filipenko NR, Attwell S, Roskelley C, Dedhar S.

Oncogene. 2005 Sep 1;24(38):5837-49.


Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.

Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.

J Cell Biol. 1997 Apr 21;137(2):387-98.


Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration.

Cai D, Chen SC, Prasad M, He L, Wang X, Choesmel-Cadamuro V, Sawyer JK, Danuser G, Montell DJ.

Cell. 2014 May 22;157(5):1146-59. doi: 10.1016/j.cell.2014.03.045.


Rac1 GTPase acts downstream of αPS1βPS integrin to control collective migration and lumen size in the Drosophila salivary gland.

Pirraglia C, Walters J, Ahn N, Myat MM.

Dev Biol. 2013 May 1;377(1):21-32. doi: 10.1016/j.ydbio.2013.02.020.

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