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Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.

Khairallah RJ, Sparagna GC, Khanna N, O'Shea KM, Hecker PA, Kristian T, Fiskum G, Des Rosiers C, Polster BM, Stanley WC.

Biochim Biophys Acta. 2010 Aug;1797(8):1555-62. doi: 10.1016/j.bbabio.2010.05.007. Epub 2010 May 21.


Treatment with docosahexaenoic acid, but not eicosapentaenoic acid, delays Ca2+-induced mitochondria permeability transition in normal and hypertrophied myocardium.

Khairallah RJ, O'Shea KM, Brown BH, Khanna N, Des Rosiers C, Stanley WC.

J Pharmacol Exp Ther. 2010 Oct;335(1):155-62. doi: 10.1124/jpet.110.170605. Epub 2010 Jul 12.


Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.

O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC.

J Mol Cell Cardiol. 2009 Dec;47(6):819-27. doi: 10.1016/j.yjmcc.2009.08.014. Epub 2009 Aug 22.


Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids.

Khairallah RJ, Kim J, O'Shea KM, O'Connell KA, Brown BH, Galvao T, Daneault C, Des Rosiers C, Polster BM, Hoppel CL, Stanley WC.

PLoS One. 2012;7(3):e34402. doi: 10.1371/journal.pone.0034402. Epub 2012 Mar 30.


The effects of omega-3 polyunsaturated (correction of polyunsatulated) fatty acids on the recovery of cardiac function following cold preservation and reperfusion in hyperlipidemic rats.

Ku K, Nosaka S, Hashimoto M, Kin S, Saitoh Y, Alam MS, Masumura S, Nakayama K.

Transplantation. 1996 Sep 27;62(6):735-42.


Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.

Galvao TF, Khairallah RJ, Dabkowski ER, Brown BH, Hecker PA, O'Connell KA, O'Shea KM, Sabbah HN, Rastogi S, Daneault C, Des Rosiers C, Stanley WC.

Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H12-21. doi: 10.1152/ajpheart.00657.2012. Epub 2012 Oct 26.


Polyunsaturated fatty acids incorporation into cardiolipin in H9c2 cardiac myoblast.

Ting HC, Chao YJ, Hsu YH.

J Nutr Biochem. 2015 Jul;26(7):769-75. doi: 10.1016/j.jnutbio.2015.02.005. Epub 2015 Mar 26.


Individual effects of dietary EPA and DHA on the functioning of the isolated working rat heart.

Sergiel JP, Martine L, Raederstorff D, Grynberg A, Demaison L.

Can J Physiol Pharmacol. 1998 Jul-Aug;76(7-8):728-36.


Update on lipids and mitochondrial function: impact of dietary n-3 polyunsaturated fatty acids.

Stanley WC, Khairallah RJ, Dabkowski ER.

Curr Opin Clin Nutr Metab Care. 2012 Mar;15(2):122-6. doi: 10.1097/MCO.0b013e32834fdaf7. Review.


Docosahexaenoic acid and eicosapentaenoic acid affect ovarian prostaglandin levels differently in rats.

Broughton KS, Hahn B, Ross E.

Nutr Res. 2009 Jul;29(7):510-8. doi: 10.1016/j.nutres.2009.06.003.


Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution.

Rühl R, Koch C, Marosvölgyi T, Mihály J, Schweigert FJ, Worm M, Decsi T.

Br J Nutr. 2008 Jun;99(6):1239-46. Epub 2007 Nov 16.


Docosahexaenoic acid supplementation alters key properties of cardiac mitochondria and modestly attenuates development of left ventricular dysfunction in pressure overload-induced heart failure.

Dabkowski ER, O'Connell KA, Xu W, Ribeiro RF Jr, Hecker PA, Shekar KC, Daneault C, Des Rosiers C, Stanley WC.

Cardiovasc Drugs Ther. 2013 Dec;27(6):499-510. doi: 10.1007/s10557-013-6487-4.


Membrane fluidity and fatty acid metabolism in kidney cells from rats fed purified eicosapentaenoic acid or purified docosahexaenoic acid.

Hagve TA, Woldseth B, Brox J, Narce M, Poisson JP.

Scand J Clin Lab Invest. 1998 May;58(3):187-94.


Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation.

Schnebelen C, Viau S, Grégoire S, Joffre C, Creuzot-Garcher CP, Bron AM, Bretillon L, Acar N.

Ophthalmic Res. 2009;41(4):216-24. doi: 10.1159/000217726. Epub 2009 May 15.


Effect of fish oils containing different amounts of EPA, DHA, and antioxidants on plasma and brain fatty acids and brain nitric oxide synthase activity in rats.

Engström K, Saldeen AS, Yang B, Mehta JL, Saldeen T.

Ups J Med Sci. 2009;114(4):206-13. doi: 10.3109/03009730903268958.

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