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Items: 1 to 20 of 96

1.

Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.

Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J.

Neurobiol Aging. 2011 Dec;32(12):2113-22. doi: 10.1016/j.neurobiolaging.2010.01.010. Epub 2010 May 7.

2.

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I.

J Neurosci. 2010 Jul 7;30(27):9228-40. doi: 10.1523/JNEUROSCI.0418-10.2010.

3.

Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease.

Miyashita A, Hatsuta H, Kikuchi M, Nakaya A, Saito Y, Tsukie T, Hara N, Ogishima S, Kitamura N, Akazawa K, Kakita A, Takahashi H, Murayama S, Ihara Y, Ikeuchi T, Kuwano R; Japanese Alzheimer's Disease Neuroimaging Initiative.

Transl Psychiatry. 2014 Jun 10;4:e396. doi: 10.1038/tp.2014.35.

4.

Reelin signaling pathway genotypes and Alzheimer disease in a Spanish population.

Bufill E, Roura-Poch P, Sala-Matavera I, Antón S, Lleó A, Sánchez-Saudinós B, Tomàs-Abadal L, Puig T, Abós J, Bernades S, Clarimon J, Blesa R.

Alzheimer Dis Assoc Disord. 2015 Apr-Jun;29(2):169-72. doi: 10.1097/WAD.0000000000000002.

PMID:
24384746
5.

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L.

J Neurosci. 2007 Mar 14;27(11):2727-33.

6.

Genetic analysis of the RELN gene: Gender specific association with Alzheimer's disease.

Fehér Á, Juhász A, Pákáski M, Kálmán J, Janka Z.

Psychiatry Res. 2015 Dec 15;230(2):716-8. doi: 10.1016/j.psychres.2015.09.021. Epub 2015 Sep 13.

PMID:
26384575
7.

A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.

Schrauwen I, Ealy M, Huentelman MJ, Thys M, Homer N, Vanderstraeten K, Fransen E, Corneveaux JJ, Craig DW, Claustres M, Cremers CW, Dhooge I, Van de Heyning P, Vincent R, Offeciers E, Smith RJ, Van Camp G.

Am J Hum Genet. 2009 Mar;84(3):328-38. doi: 10.1016/j.ajhg.2009.01.023. Epub 2009 Feb 19.

8.

The RELN locus in Alzheimer's disease.

Seripa D, Matera MG, Franceschi M, Daniele A, Bizzarro A, Rinaldi M, Panza F, Fazio VM, Gravina C, D'Onofrio G, Solfrizzi V, Masullo C, Pilotto A.

J Alzheimers Dis. 2008 Jul;14(3):335-44.

PMID:
18599960
9.

Co-localization of Reelin and proteolytic AbetaPP fragments in hippocampal plaques in aged wild-type mice.

Doehner J, Madhusudan A, Konietzko U, Fritschy JM, Knuesel I.

J Alzheimers Dis. 2010;19(4):1339-57. doi: 10.3233/JAD-2010-1333.

PMID:
20061602
10.

Reelin depletion is an early phenomenon of Alzheimer's pathology.

Herring A, Donath A, Steiner KM, Widera MP, Hamzehian S, Kanakis D, Kölble K, ElAli A, Hermann DM, Paulus W, Keyvani K.

J Alzheimers Dis. 2012;30(4):963-79. doi: 10.3233/JAD-2012-112069.

PMID:
22495348
11.

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

Mota SI, Ferreira IL, Valero J, Ferreiro E, Carvalho AL, Oliveira CR, Rego AC.

Exp Neurol. 2014 Nov;261:698-709. doi: 10.1016/j.expneurol.2014.07.023. Epub 2014 Aug 13.

PMID:
25128699
12.

Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn Down syndrome mice.

Kern DS, Maclean KN, Jiang H, Synder EY, Sladek JR Jr, Bjugstad KB.

Cell Transplant. 2011;20(3):371-9. doi: 10.3727/096368910X528085. Epub 2010 Sep 27.

PMID:
20875225
13.

14-3-3 protein beta isoform is associated with 3-repeat tau neurofibrillary tangles in Alzheimer's disease.

Sugimori K, Kobayashi K, Kitamura T, Sudo S, Koshino Y.

Psychiatry Clin Neurosci. 2007 Apr;61(2):159-67.

14.

Association and gene-gene interactions study of reelin signaling pathway related genes with autism in the Han Chinese population.

Shen Y, Xun G, Guo H, He Y, Ou J, Dong H, Xia K, Zhao J.

Autism Res. 2016 Apr;9(4):436-42. doi: 10.1002/aur.1540. Epub 2015 Aug 19.

PMID:
26285919
15.

Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.

Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL.

Am J Hum Genet. 2011 Feb 11;88(2):232-8. doi: 10.1016/j.ajhg.2011.01.006. Epub 2011 Feb 3.

16.

Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications.

Deutsch SI, Rosse RB, Lakshman RM.

Prog Neuropsychopharmacol Biol Psychiatry. 2006 Dec 30;30(8):1369-80. Epub 2006 Jun 21. Review.

PMID:
16793187
17.

Epigenetic silencing of RELN in gastric cancer.

Dohi O, Takada H, Wakabayashi N, Yasui K, Sakakura C, Mitsufuji S, Naito Y, Taniwaki M, Yoshikawa T.

Int J Oncol. 2010 Jan;36(1):85-92.

PMID:
19956836
18.

Impact of the Reelin signaling cascade (ligands-receptors-adaptor complex) on cognition in schizophrenia.

Verbrugghe P, Bouwer S, Wiltshire S, Carter K, Chandler D, Cooper M, Morar B, Razif MF, Henders A, Badcock JC, Dragovic M, Carr V, Almeida OP, Flicker L, Montgomery G, Jablensky A, Kalaydjieva L.

Am J Med Genet B Neuropsychiatr Genet. 2012 Jun;159B(4):392-404. doi: 10.1002/ajmg.b.32042. Epub 2012 Mar 14.

PMID:
22419519
19.

Association of reelin (RELN) single nucleotide polymorphism rs7341475 with prepulse inhibition in the Jewish Israeli population.

Greenbaum L, Levin R, Lerer E, Alkelai A, Kohn Y, Heresco-Levy U, Ebstein RP, Lerer B.

Biol Psychiatry. 2011 Mar 1;69(5):e17-8; author reply e19. doi: 10.1016/j.biopsych.2010.09.059. Epub 2010 Dec 31. No abstract available.

PMID:
21195391
20.

No significant association between RELN polymorphism and autism in case-control and family-based association study in Chinese Han population.

He Y, Xun G, Xia K, Hu Z, Lv L, Deng Z, Zhao J.

Psychiatry Res. 2011 May 30;187(3):462-4. doi: 10.1016/j.psychres.2010.04.051. Epub 2011 Apr 7.

PMID:
20554015

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