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Items: 1 to 20 of 90

1.

Induction of the apoptosis inhibitor ARC by Ras in human cancers.

Wu L, Nam YJ, Kung G, Crow MT, Kitsis RN.

J Biol Chem. 2010 Jun 18;285(25):19235-45. doi: 10.1074/jbc.M110.114892. Epub 2010 Apr 14.

2.

Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.

Mak PY, Mak DH, Mu H, Shi Y, Ruvolo P, Ruvolo V, Jacamo R, Burks JK, Wei W, Huang X, Kornblau SM, Andreeff M, Carter BZ.

Apoptosis. 2014 Apr;19(4):698-707. doi: 10.1007/s10495-013-0954-z.

3.

Regulation of p53 tetramerization and nuclear export by ARC.

Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, Caldas C, Kitsis RN.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20826-31. Epub 2007 Dec 17.

4.

The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression.

Barradas M, Monjas A, Diaz-Meco MT, Serrano M, Moscat J.

EMBO J. 1999 Nov 15;18(22):6362-9.

5.

Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.

Yuen HF, Chan KK, Grills C, Murray JT, Platt-Higgins A, Eldin OS, O'Byrne K, Janne P, Fennell DA, Johnston PG, Rudland PS, El-Tanani M.

Clin Cancer Res. 2012 Jan 15;18(2):380-91. doi: 10.1158/1078-0432.CCR-11-2035. Epub 2011 Nov 16.

6.

ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer.

Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN.

Cell Cycle. 2008 Jun 1;7(11):1640-7. Epub 2008 Mar 19.

PMID:
18469522
7.

Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-Ras.

Sommer KW, Schamberger CJ, Schmidt GE, Sasgary S, Cerni C.

Oncogene. 2003 Jul 3;22(27):4266-80.

PMID:
12833149
8.

Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras.

Vasudevan KM, Burikhanov R, Goswami A, Rangnekar VM.

Cancer Res. 2007 Nov 1;67(21):10343-50.

9.

H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells.

Shin I, Kim S, Song H, Kim HR, Moon A.

J Biol Chem. 2005 Apr 15;280(15):14675-83. Epub 2005 Jan 27.

10.

Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks.

Tabu K, Kimura T, Sasai K, Wang L, Bizen N, Nishihara H, Taga T, Tanaka S.

Mol Cancer. 2010 Feb 19;9:39. doi: 10.1186/1476-4598-9-39.

11.

Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.

Drosopoulos KG, Roberts ML, Cermak L, Sasazuki T, Shirasawa S, Andera L, Pintzas A.

J Biol Chem. 2005 Jun 17;280(24):22856-67. Epub 2005 Mar 8.

12.

Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis, and chemoresistance.

Medina-Ramirez CM, Goswami S, Smirnova T, Bamira D, Benson B, Ferrick N, Segall J, Pollard JW, Kitsis RN.

Cancer Res. 2011 Dec 15;71(24):7705-15. doi: 10.1158/0008-5472.CAN-11-2192. Epub 2011 Oct 28.

13.

The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-α expression.

Robbs BK, Lucena PI, Viola JP.

Biochim Biophys Acta. 2013 Aug;1833(8):2016-28. doi: 10.1016/j.bbamcr.2013.04.003. Epub 2013 Apr 10.

14.
15.

The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal.

Banerjee P, Basu A, Datta D, Gasser M, Waaga-Gasser AM, Pal S.

J Biol Chem. 2011 Sep 23;286(38):33580-90. doi: 10.1074/jbc.M111.248401. Epub 2011 Jul 31.

16.
17.

Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.

Caraglia M, Marra M, Mancinelli F, D'Ambrosio G, Massa R, Giordano A, Budillon A, Abbruzzese A, Bismuto E.

J Cell Physiol. 2005 Aug;204(2):539-48.

PMID:
15754340
19.

Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein.

Chen LH, Jiang CC, Watts R, Thorne RF, Kiejda KA, Zhang XD, Hersey P.

Cancer Res. 2008 Feb 1;68(3):834-42. doi: 10.1158/0008-5472.CAN-07-5056.

20.

Mitogen-activated protein kinase phosphatase-3 is a tumor promoter target in initiated cells that express oncogenic Ras.

Warmka JK, Mauro LJ, Wattenberg EV.

J Biol Chem. 2004 Aug 6;279(32):33085-92. Epub 2004 May 24.

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