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Comparison of three anthrax toxin neutralization assays.

Ngundi MM, Meade BD, Lin TL, Tang WJ, Burns DL.

Clin Vaccine Immunol. 2010 Jun;17(6):895-903. doi: 10.1128/CVI.00513-09. Epub 2010 Apr 7.


Generation of a novel chimeric PALFn antigen of Bacillus anthracis and its immunological characterization in mouse model.

Suryanarayana N, Verma M, Thavachelvam K, Saxena N, Mankere B, Tuteja U, Hmuaka V.

Appl Microbiol Biotechnol. 2016 Oct;100(19):8439-51. doi: 10.1007/s00253-016-7684-4. Epub 2016 Jun 30.


Recombinant vaccine displaying the loop-neutralizing determinant from protective antigen completely protects rabbits from experimental inhalation anthrax.

Oscherwitz J, Yu F, Jacobs JL, Cease KB.

Clin Vaccine Immunol. 2013 Mar;20(3):341-9. doi: 10.1128/CVI.00612-12. Epub 2013 Jan 2.


Standardized, mathematical model-based and validated in vitro analysis of anthrax lethal toxin neutralization.

Li H, Soroka SD, Taylor TH Jr, Stamey KL, Stinson KW, Freeman AE, Abramson DR, Desai R, Cronin LX, Oxford JW, Caba J, Pleatman C, Pathak S, Schmidt DS, Semenova VA, Martin SK, Wilkins PP, Quinn CP.

J Immunol Methods. 2008 Apr 20;333(1-2):89-106. doi: 10.1016/j.jim.2008.01.007. Epub 2008 Feb 8.


Efficacy and immunogenicity of single-dose AdVAV intranasal anthrax vaccine compared to anthrax vaccine absorbed in an aerosolized spore rabbit challenge model.

Krishnan V, Andersen BH, Shoemaker C, Sivko GS, Tordoff KP, Stark GV, Zhang J, Feng T, Duchars M, Roberts MS.

Clin Vaccine Immunol. 2015 Apr;22(4):430-9. doi: 10.1128/CVI.00690-14. Epub 2015 Feb 11.


A plant based protective antigen [PA(dIV)] vaccine expressed in chloroplasts demonstrates protective immunity in mice against anthrax.

Gorantala J, Grover S, Goel D, Rahi A, Jayadev Magani SK, Chandra S, Bhatnagar R.

Vaccine. 2011 Jun 15;29(27):4521-33. doi: 10.1016/j.vaccine.2011.03.082. Epub 2011 Apr 17.


Comparability of ELISA and toxin neutralization to measure immunogenicity of Protective Antigen in mice, as part of a potency test for anthrax vaccines.

Parreiras PM, Sirota LA, Wagner LD, Menzies SL, Arciniega JL.

Vaccine. 2009 Jul 16;27(33):4537-42. doi: 10.1016/j.vaccine.2009.05.045. Epub 2009 Jun 6.


Selection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates.

Yan M, Roehrl MH, Basar E, Wang JY.

Vaccine. 2008 Feb 13;26(7):947-55. doi: 10.1016/j.vaccine.2007.11.087. Epub 2007 Dec 26.


Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.

Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH.

PLoS One. 2015 Jul 24;10(7):e0130952. doi: 10.1371/journal.pone.0130952. eCollection 2015.


Ability of ELISA and a toxin neutralization assay to detect changes in immunogenicity of a recombinant Bacillus anthracis protective antigen vaccine upon storage.

Domínguez-Castillo RI, Verma A, Amador-Molina JC, Sirota L, Arciniega JL.

Biologicals. 2013 Mar;41(2):111-4. doi: 10.1016/j.biologicals.2012.10.002. Epub 2012 Nov 6.


Immunogenicity of Bacillus anthracis protective antigen domains and efficacy of elicited antibody responses depend on host genetic background.

Abboud N, Casadevall A.

Clin Vaccine Immunol. 2008 Jul;15(7):1115-23. doi: 10.1128/CVI.00015-08. Epub 2008 May 14.


Characterization of the native form of anthrax lethal factor for use in the toxin neutralization assay.

Lu H, Catania J, Baranji K, Feng J, Gu M, Lathey J, Sweeny D, Sanford H, Sapru K, Patamawenu T, Chen JH, Ng A, Fesseha Z, Kluepfel-Stahl S, Minang J, Alleva D.

Clin Vaccine Immunol. 2013 Jul;20(7):986-97. doi: 10.1128/CVI.00046-13. Epub 2013 May 1.


A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-Immunization Protection against Inhaled Anthrax in Monkeys.

Kachura MA, Hickle C, Kell SA, Sathe A, Calacsan C, Kiwan R, Hall B, Milley R, Ott G, Coffman RL, Kanzler H, Campbell JD.

J Immunol. 2016 Jan 1;196(1):284-97. doi: 10.4049/jimmunol.1501903. Epub 2015 Nov 25.


Vaccination of rhesus macaques with the anthrax vaccine adsorbed vaccine produces a serum antibody response that effectively neutralizes receptor-bound protective antigen in vitro.

Clement KH, Rudge TL Jr, Mayfield HJ, Carlton LA, Hester A, Niemuth NA, Sabourin CL, Brys AM, Quinn CP.

Clin Vaccine Immunol. 2010 Nov;17(11):1753-62. doi: 10.1128/CVI.00174-10. Epub 2010 Aug 25.


Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays.

Verma A, Ngundi MM, Meade BD, De Pascalis R, Elkins KL, Burns DL.

Clin Vaccine Immunol. 2009 Oct;16(10):1405-12. doi: 10.1128/CVI.00194-09. Epub 2009 Aug 5.


Detoxified lethal toxin as a potential mucosal vaccine against anthrax.

Xu Q, Zeng M.

Clin Vaccine Immunol. 2008 Apr;15(4):612-6. doi: 10.1128/CVI.00402-07. Epub 2008 Feb 6.


Phase 1 study of a recombinant mutant protective antigen of Bacillus anthracis.

Bellanti JA, Lin FY, Chu C, Shiloach J, Leppla SH, Benavides GA, Karpas A, Moayeri M, Guo C, Robbins JB, Schneerson R.

Clin Vaccine Immunol. 2012 Feb;19(2):140-5. doi: 10.1128/CVI.05556-11. Epub 2011 Dec 21.

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