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Items: 1 to 20 of 128

1.

Severe X-linked mitochondrial encephalomyopathy associated with a mutation in apoptosis-inducing factor.

Ghezzi D, Sevrioukova I, Invernizzi F, Lamperti C, Mora M, D'Adamo P, Novara F, Zuffardi O, Uziel G, Zeviani M.

Am J Hum Genet. 2010 Apr 9;86(4):639-49. doi: 10.1016/j.ajhg.2010.03.002. Epub 2010 Apr 1.

2.

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).

Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, Poirier GG, Dawson VL, Dawson TM.

Sci Signal. 2011 Apr 5;4(167):ra20. doi: 10.1126/scisignal.2000902.

3.

Cowchock syndrome is associated with a mutation in apoptosis-inducing factor.

Rinaldi C, Grunseich C, Sevrioukova IF, Schindler A, Horkayne-Szakaly I, Lamperti C, Landouré G, Kennerson ML, Burnett BG, Bönnemann C, Biesecker LG, Ghezzi D, Zeviani M, Fischbeck KH.

Am J Hum Genet. 2012 Dec 7;91(6):1095-102. doi: 10.1016/j.ajhg.2012.10.008.

4.

Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.

Kondo K, Obitsu S, Ohta S, Matsunami K, Otsuka H, Teshima R.

J Biol Chem. 2010 Apr 23;285(17):13079-91. doi: 10.1074/jbc.M109.044206. Epub 2010 Feb 22.

5.

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).

Wang Y, Kim NS, Li X, Greer PA, Koehler RC, Dawson VL, Dawson TM.

J Neurochem. 2009 Jul;110(2):687-96. doi: 10.1111/j.1471-4159.2009.06167.x. Epub 2009 May 13.

6.

Apoptosis-inducing factor: structure, function, and redox regulation.

Sevrioukova IF.

Antioxid Redox Signal. 2011 Jun 15;14(12):2545-79. doi: 10.1089/ars.2010.3445. Epub 2011 Mar 10. Review.

7.

Apoptosis-inducing Factor (AIF) and Its Family Member Protein, AMID, Are Rotenone-sensitive NADH:Ubiquinone Oxidoreductases (NDH-2).

Elguindy MM, Nakamaru-Ogiso E.

J Biol Chem. 2015 Aug 21;290(34):20815-26. doi: 10.1074/jbc.M115.641498. Epub 2015 Jun 10.

8.

Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos.

Wang Y, Dawson VL, Dawson TM.

Exp Neurol. 2009 Aug;218(2):193-202. doi: 10.1016/j.expneurol.2009.03.020. Epub 2009 Mar 28. Review.

9.

Structure/Function Relations in AIFM1 Variants Associated with Neurodegenerative Disorders.

Sevrioukova IF.

J Mol Biol. 2016 Sep 11;428(18):3650-65. doi: 10.1016/j.jmb.2016.05.004. Epub 2016 May 10.

PMID:
27178839
10.

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA.

Mol Cell Biol. 2007 Jul;27(13):4844-62. Epub 2007 Apr 30.

12.

The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?

Ferreira P, Villanueva R, Cabon L, Susín SA, Medina M.

Curr Pharm Des. 2013;19(14):2628-36. Review.

PMID:
23116400
13.

AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX.

Artus C, Boujrad H, Bouharrour A, Brunelle MN, Hoos S, Yuste VJ, Lenormand P, Rousselle JC, Namane A, England P, Lorenzo HK, Susin SA.

EMBO J. 2010 May 5;29(9):1585-99. doi: 10.1038/emboj.2010.43. Epub 2010 Apr 1.

14.

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities.

Fatokun AA, Dawson VL, Dawson TM.

Br J Pharmacol. 2014 Apr;171(8):2000-16. doi: 10.1111/bph.12416. Review.

15.
16.

Mitochondrial encephalomyopathy due to a novel mutation in ACAD9.

Garone C, Donati MA, Sacchini M, Garcia-Diaz B, Bruno C, Calvo S, Mootha VK, Dimauro S.

JAMA Neurol. 2013 Sep 1;70(9):1177-9. doi: 10.1001/jamaneurol.2013.3197.

17.

Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.

Zhou Y, Feng X, Koh DW.

Biochemistry. 2011 Apr 12;50(14):2850-9. doi: 10.1021/bi101829r. Epub 2011 Mar 21.

PMID:
21366272
18.

Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina.

Martín-Oliva D, Ferrer-Martín RM, Santos AM, Carrasco MC, Sierra A, Marín-Teva JL, Calvente R, Navascués J, Cuadros MA.

Invest Ophthalmol Vis Sci. 2011 Sep 27;52(10):7445-54. doi: 10.1167/iovs.11-7222.

PMID:
21705688
19.

Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor.

Sorrentino L, Calogero AM, Pandini V, Vanoni MA, Sevrioukova IF, Aliverti A.

Biochemistry. 2015 Dec 1;54(47):6996-7009. doi: 10.1021/acs.biochem.5b00898. Epub 2015 Nov 16.

PMID:
26535916
20.

Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: a mechanistic study.

Misevičienė L, Anusevičius Z, Sarlauskas J, Sevrioukova IF, Cėnas N.

Arch Biochem Biophys. 2011 Aug 15;512(2):183-9. doi: 10.1016/j.abb.2011.05.015. Epub 2011 Jun 2.

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