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Items: 1 to 20 of 92

1.

Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.

Kinder M, Wei C, Shelat SG, Kundu M, Zhao L, Blair IA, Puré E.

Blood. 2010 Jun 17;115(24):5012-22. doi: 10.1182/blood-2009-09-243139.

2.

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency.

Taylor PR, Heydeck D, Jones GW, Krönke G, Funk CD, Knapper S, Adams D, Kühn H, O'Donnell VB.

Blood. 2012 Jun 21;119(25):6173-4; author reply 6174-5. doi: 10.1182/blood-2012-02-410928. No abstract available.

3.

Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.

Kinder M, Thompson JE, Wei C, Shelat SG, Blair IA, Carroll M, Puré E.

Exp Hematol. 2010 Nov;38(11):1036-1046.e1-4. doi: 10.1016/j.exphem.2010.07.004.

4.

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA.

Blood. 2010 May 20;115(20):4030-8. doi: 10.1182/blood-2009-09-241000.

5.

Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.

Teder T, Boeglin WE, Brash AR.

J Lipid Res. 2014 Dec;55(12):2587-96. doi: 10.1194/jlr.M054072.

6.
7.

Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice.

Singh KP, Bennett JA, Casado FL, Walrath JL, Welle SL, Gasiewicz TA.

Stem Cells Dev. 2014 Jan 15;23(2):95-106. doi: 10.1089/scd.2013.0346.

8.

Suppression of cytochrome p450 reductase enhances long-term hematopoietic stem cell repopulation efficiency in mice.

Zhang Y, Dong F, Zhang N, Cheng H, Pang Y, Wang X, Xu J, Ding X, Cheng T, Gu J, Yuan W.

PLoS One. 2013 Jul 26;8(7):e69913. doi: 10.1371/journal.pone.0069913.

9.
10.

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function.

Chitteti BR, Cheng YH, Poteat B, Rodriguez-Rodriguez S, Goebel WS, Carlesso N, Kacena MA, Srour EF.

Blood. 2010 Apr 22;115(16):3239-48. doi: 10.1182/blood-2009-09-246173.

11.

Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase.

Sukhanov S, Snarski P, Vaughn C, Lobelle-Rich P, Kim C, Higashi Y, Shai SY, Delafontaine P.

Atherosclerosis. 2015 Feb;238(2):313-20. doi: 10.1016/j.atherosclerosis.2014.12.024.

12.

Enhancement role of host 12/15-lipoxygenase in melanoma progression.

Kang KH, Ling TY, Liou HH, Huang YK, Hour MJ, Liou HC, Fu WM.

Eur J Cancer. 2013 Aug;49(12):2747-59. doi: 10.1016/j.ejca.2013.03.030.

PMID:
23664097
13.

Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo.

Larsson J, Blank U, Klintman J, Magnusson M, Karlsson S.

Exp Hematol. 2005 May;33(5):592-6.

PMID:
15850837
14.

Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.

Trowbridge JJ, Xenocostas A, Moon RT, Bhatia M.

Nat Med. 2006 Jan;12(1):89-98.

PMID:
16341242
15.

Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor.

Povinelli BJ, Nemeth MJ.

Stem Cells. 2014 Jan;32(1):105-15. doi: 10.1002/stem.1513.

16.

Mice severely deficient in growth hormone have normal hematopoiesis.

Sharma Y, Flurkey K, Astle CM, Harrison DE.

Exp Hematol. 2005 Jul;33(7):776-83.

PMID:
15963853
17.

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.

Scheller M, Huelsken J, Rosenbauer F, Taketo MM, Birchmeier W, Tenen DG, Leutz A.

Nat Immunol. 2006 Oct;7(10):1037-47.

PMID:
16951686
18.

Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells.

Brun AC, Björnsson JM, Magnusson M, Larsson N, Leveén P, Ehinger M, Nilsson E, Karlsson S.

Blood. 2004 Jun 1;103(11):4126-33.

19.

Cytosolic phospholipase A(2), lipoxygenase metabolites, and reactive oxygen species.

Kim C, Kim JY, Kim JH.

BMB Rep. 2008 Aug 31;41(8):555-9. Review.

20.

Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche.

Kim JA, Kang YJ, Park G, Kim M, Park YO, Kim H, Leem SH, Chu IS, Lee JS, Jho EH, Oh IH.

Stem Cells. 2009 Jun;27(6):1318-29. doi: 10.1002/stem.52.

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