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20308655,18756530,20308652,19901110,18071985,14981983,15800329,24495592,28360216,11870182,27590514,18445844,19240962,16088964,19016015,15499296,18554821,28272232,19640635,22483738,24995786,15015788,20932651,19836157,20439646,19506159,26194676,20925470,19303779,23129347,19514084,20436394,15073861,20167817,22079725,20850883,20217098,29683790,27557526,11870183,19647954,15266331,19533023,21709196,22037649,23898108,21984132,16735709,16891823,10944597,25582142,26520780,16368514,21450506,20706757,15117981,19672263,24608453,24555238,15279717,18651326,15925979,16983109,25931361,16270316,20862518,15022289,15380566,28798282,21399487,20169771,19683876,11772431,26285766,22105851,21858417,19636006,12865911,29937336,21135282,23254891,23649997,20855843,21057562,18231723,11300335,29694955,19414327,18574933,25739547,19579865,22035272,24125970,20656474,29199725,17361334,25920710,22382781,20627551,26588662,17679463,19150114,29741106,30771200,19831132,22680781,19628288,23898121,18389176,28510787,17549280,25947286,19061770,23299464,25366363,26842817,15565458,26481741,22583678,20150372,28424876,23570586,23932193,20345222,27370396,20805645,19945857,10735896,19716649,18955445,23633341,28586949,25595963,19902821,16200343,37006062,19688972,27384182,26033428,20526650,18359865,18559468,27770279,19705066,19221744,34724914,22419509,22110212,12356356,12187069,23279669,27725524,20921459,16794761,16944309,25419975,27177177,20167815,19169684,20017331,22689800,26506875,23898124,27096953,16292488,29555610,23043578,23845846,16097842,24723487,15527106,26574999,24975917,21672702,26847813,25466729,19273412,21606416,19901101,26025933,23974823,21766499,27209069,23764039,21479583,19652936,24046259,21725801,24571331,23642624,27571885,28204914,33609154,22169729,18688571,36357822,31399318,28192785,20684359,19204199,20001586,21035955,16709037,16533878,21839964,19117668,17576523,25997057,19718545,18035958,11300334,28288919,27117900,21755329,20936460,17031561,20652724,23633392,27688162,28467795,16944366,25815327,17036520,24063865,26325605,22257825,29366782,24991840,26019185,16645714,25886314,18790951,16047359,20064829,22634799,18091279,30687753,26960490,20672935,24303044,19014782,25151509,26508094,25017996,25139026,27739940,21987286,15184628,26025775,24328555,18480965,21149254,12125988,25586468,19248684,28806010,25744349,25449156,17596744,22984531,23292205,15865885,28500556,22391876,17019532,20443129,26601809,28116649,21464805,31427282,25158679,19688297,14630674,27006176,20137866,24101048,20440539,22407174,25526733,19289491,15069758,19669096,28791452,19543728,15870090,16639492,19402172,24469853,16944365,28570014,26323606,16283445,25572329,31752981,20838208,24894840,26423602,22923449,32602292,28301347,10561351,28411277,28708230,27271867,22825126,25140039,20811928,25045231,32167589,29516964,26408725,24442484,25680596,19533661,9486616,19846986,27494880,22850321,29264836,26576125,25585997,30580645,21327711,20922459,11989929,27022952,23519741,20878446,24337403,26203687,29979390,21709193,23099652,28423558,16710748,18283418,21344976,23133490,14630675,24291476,10871815,22341931,27535747,15527114,15514370,19212704,22576807,28717885,11550320,12952497,17505778,18843749,12088355,11870527,28485350,10561325,20626200,19840807,31707687,29050959,21735117,19569246,28371832,15159792,24908656,19817543,23362460,27876012,9256890,33589792,15072451,21515959,29606522,20434832,34787778,22340055,27893419,26309255,22639157,25286037,25554223,21036812,21432029,21181283,23064578,28666727,23861829,34275586,25535132,36735492,20205087,30496882,18477765,32799864,27359377,19107490,23666235,27840944,19663635,26547911,18728637,29412784,29749548,25982679,18175205,28867360,10673511,11870507,26345664,27716874,26053493,22141295,21302627,30515706,19521065,30155806,24849425,23527068,23224713,21791942,25854526,14630671,29982805,28586748,36464967,17074680,22674154,18987781,9480566,29356965,29022050,26373279,20431907,28314286,15173079,31351210,29899179,21844505,29990984,23211224,26334318,11083075,19668033,18690931,28551545,17082887,29807183,28668896,20128997,21805051,30726533,1560258,25644286,25262961,19221865,19210148,34609773,37026351,23459995,24141458,32328662,11550133,19001677,24264531,31994757,24463354,20930514,29135107,21516367,15304589,26559642,25053853,25751368,18990027,25055819,30359477,32988908,19239041,23870657,23793813,14765377,15735923,32778906,24610705,29923272,22832897,21809177,28658891,29298660,29349602,26713142,16146748,32847475,29143923,33783067,12416546,23775421,15727424,26843484,19489660,26454859,26936394,32674977,27458167,2553234,29162424,29978325,29774875,24732058,20564393,15072473,27300524,19337695,22897453,16450140,21149665,17929115,12569300,24163082,22946346,17031557,30080691,24336570,18618580,33284237,31050315,21865400,18676355,23101195,11568904,25576318,36001203,25948789,31325145,11212902,20063175,20401670,11212905,9266443,21158849,27003178,29972422,19881333,26881656,30125556,20658636,24616497,31154345,15174524,25773653,21269334,7572767,18974931,19018476,20150385,36870087,220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Results by year

Year	Number of Results
1959	1
1969	1
1972	1
1979	1
1983	1
1989	1
1991	1
1992	4
1993	1
1994	1
1995	4
1996	1
1997	5
1998	3
1999	11
2000	9
2001	7
2002	16
2003	16
2004	21
2005	15
2006	29
2007	18
2008	39
2009	65
2010	77
2011	67
2012	52
2013	51
2014	60
2015	82
2016	58
2017	58
2018	62
2019	35
2020	30
2021	29
2022	24
2023	6
2024	0

837 results

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Results by year

Page 1

Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.

Perry JR, Bélanger K, Mason WP, Fulton D, Kavan P, Easaw J, Shields C, Kirby S, Macdonald DR, Eisenstat DD, Thiessen B, Forsyth P, Pouliot JF. Perry JR, et al. J Clin Oncol. 2010 Apr 20;28(12):2051-7. doi: 10.1200/JCO.2009.26.5520. Epub 2010 Mar 22. J Clin Oncol. 2010. PMID: 20308655 Clinical Trial.

Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the "rescue" approach.

Perry JR, Rizek P, Cashman R, Morrison M, Morrison T. Perry JR, et al. Cancer. 2008 Oct 15;113(8):2152-7. doi: 10.1002/cncr.23813. Cancer. 2008. PMID: 18756530 Free article.

Therapy for recurrent high-grade gliomas: does continuous dose-intense temozolomide have a role?

Wen PY. Wen PY. J Clin Oncol. 2010 Apr 20;28(12):1977-9. doi: 10.1200/JCO.2009.27.6014. Epub 2010 Mar 22. J Clin Oncol. 2010. PMID: 20308652 No abstract available.

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.

Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, Sabel MC, Koeppen S, Ketter R, Meyermann R, Rapp M, Meisner C, Kortmann RD, Pietsch T, Wiestler OD, Ernemann U, Bamberg M, Reifenberger G, von Deimling A, Weller M. Wick W, et al. J Clin Oncol. 2009 Dec 10;27(35):5874-80. doi: 10.1200/JCO.2009.23.6497. Epub 2009 Nov 9. J Clin Oncol. 2009. PMID: 19901110 Clinical Trial.

Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience.

Jalali R, Basu A, Gupta T, Munshi A, Menon H, Sarin R, Goel A. Jalali R, et al. Br J Neurosurg. 2007 Dec;21(6):583-7. doi: 10.1080/02688690701604574. Br J Neurosurg. 2007. PMID: 18071985

Temozolomide in radio-chemotherapy combined treatment for newly-diagnosed glioblastoma multiforme: phase II clinical trial.

Lanzetta G, Campanella C, Rozzi A, Nappa M, Costa A, Fedele F, Innocenzi G, Gagliardi FM, Salvati M, Minniti G, Frati A, Frati L, Vecchione A. Lanzetta G, et al. Anticancer Res. 2003 Nov-Dec;23(6D):5159-64. Anticancer Res. 2003. PMID: 14981983 Clinical Trial.

Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme.

Athanassiou H, Synodinou M, Maragoudakis E, Paraskevaidis M, Verigos C, Misailidou D, Antonadou D, Saris G, Beroukas K, Karageorgis P. Athanassiou H, et al. J Clin Oncol. 2005 Apr 1;23(10):2372-7. doi: 10.1200/JCO.2005.00.331. J Clin Oncol. 2005. PMID: 15800329 Clinical Trial.

Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.

Iuchi T, Hatano K, Kodama T, Sakaida T, Yokoi S, Kawasaki K, Hasegawa Y, Hara R. Iuchi T, et al. Int J Radiat Oncol Biol Phys. 2014 Mar 15;88(4):793-800. doi: 10.1016/j.ijrobp.2013.12.011. Epub 2014 Feb 1. Int J Radiat Oncol Biol Phys. 2014. PMID: 24495592 Clinical Trial.

Prolonged Temozolomide Maintenance Therapy in Newly Diagnosed Glioblastoma.

Skardelly M, Dangel E, Gohde J, Noell S, Behling F, Lepski G, Borchers C, Koch M, Schittenhelm J, Bisdas S, Naumann A, Paulsen F, Zips D, von Hehn U, Ritz R, Tatagiba MS, Tabatabai G. Skardelly M, et al. Oncologist. 2017 May;22(5):570-575. doi: 10.1634/theoncologist.2016-0347. Epub 2017 Mar 30. Oncologist. 2017. PMID: 28360216 Free PMC article.

Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide.

Stupp R, Dietrich PY, Ostermann Kraljevic S, Pica A, Maillard I, Maeder P, Meuli R, Janzer R, Pizzolato G, Miralbell R, Porchet F, Regli L, de Tribolet N, Mirimanoff RO, Leyvraz S. Stupp R, et al. J Clin Oncol. 2002 Mar 1;20(5):1375-82. doi: 10.1200/JCO.2002.20.5.1375. J Clin Oncol. 2002. PMID: 11870182 Clinical Trial.

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