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Items: 1 to 20 of 130

1.

Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses.

Wu X, Gowda NM, Kumar S, Gowda DC.

J Immunol. 2010 Apr 15;184(8):4338-48. doi: 10.4049/jimmunol.0903824. Epub 2010 Mar 15.

2.

The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs.

Gowda NM, Wu X, Gowda DC.

PLoS One. 2011;6(6):e20398. doi: 10.1371/journal.pone.0020398. Epub 2011 Jun 8.

3.

Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.

Pichyangkul S, Yongvanitchit K, Kum-arb U, Hemmi H, Akira S, Krieg AM, Heppner DG, Stewart VA, Hasegawa H, Looareesuwan S, Shanks GD, Miller RS.

J Immunol. 2004 Apr 15;172(8):4926-33.

4.

CD36 contributes to malaria parasite-induced pro-inflammatory cytokine production and NK and T cell activation by dendritic cells.

Gowda NM, Wu X, Kumar S, Febbraio M, Gowda DC.

PLoS One. 2013 Oct 28;8(10):e77604. doi: 10.1371/journal.pone.0077604. eCollection 2013.

6.

NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.

Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, Fischer JA, Weiss S, Kalinke U, Kunz S, Bogdan C.

J Exp Med. 2007 Apr 16;204(4):893-906. Epub 2007 Mar 26.

7.

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.

Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Brière F.

J Immunol. 2005 Nov 15;175(10):6723-32.

8.

Plasmodium falciparum: differential merozoite dose requirements for maximal production of various inflammatory cytokines.

Wu X, Gowda NM, Gowda DC.

Exp Parasitol. 2011 Jan;127(1):202-7. doi: 10.1016/j.exppara.2010.07.016. Epub 2010 Aug 3.

9.

Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cells.

Baratin M, Roetynck S, Pouvelle B, Lemmers C, Viebig NK, Johansson S, Bierling P, Scherf A, Gysin J, Vivier E, Ugolini S.

PLoS One. 2007 Feb 21;2(2):e228.

10.

Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.

Coban C, Igari Y, Yagi M, Reimer T, Koyama S, Aoshi T, Ohata K, Tsukui T, Takeshita F, Sakurai K, Ikegami T, Nakagawa A, Horii T, Nuñez G, Ishii KJ, Akira S.

Cell Host Microbe. 2010 Jan 21;7(1):50-61. doi: 10.1016/j.chom.2009.12.003.

11.

CD36 modulates proinflammatory cytokine responses to Plasmodium falciparum glycosylphosphatidylinositols and merozoites by dendritic cells.

Kumar S, Gowda NM, Wu X, Gowda RN, Gowda DC.

Parasite Immunol. 2012 Jul;34(7):372-82. doi: 10.1111/j.1365-3024.2012.01367.x.

12.

TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions.

Abou Fakher FH, Rachinel N, Klimczak M, Louis J, Doyen N.

J Immunol. 2009 Feb 1;182(3):1386-96.

13.

TLR9 and MyD88 are crucial for the development of protective immunity to malaria.

Gowda NM, Wu X, Gowda DC.

J Immunol. 2012 May 15;188(10):5073-85. doi: 10.4049/jimmunol.1102143. Epub 2012 Apr 18.

14.
15.

Antigen presentation and dendritic cell biology in malaria.

Stevenson MM, Urban BC.

Parasite Immunol. 2006 Jan-Feb;28(1-2):5-14. Review.

16.

Toll-like receptor 7 mediates early innate immune responses to malaria.

Baccarella A, Fontana MF, Chen EC, Kim CC.

Infect Immun. 2013 Dec;81(12):4431-42. doi: 10.1128/IAI.00923-13. Epub 2013 Sep 16.

17.

Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.

Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M, Kawakami K.

J Immunol. 2008 Mar 15;180(6):4067-74.

18.

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.

Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S.

J Exp Med. 2005 Jan 3;201(1):19-25.

19.

Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells.

Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L, Hamano S, Duan X, Chou B, Ishida H, Aramaki A, Shen J, Ishii KJ, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K.

J Immunol. 2008 Feb 15;180(4):2496-503.

20.

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