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Items: 1 to 20 of 51

1.

Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch.

Gielchinsky Y, Laufer N, Weitman E, Abramovitch R, Granot Z, Bergman Y, Pikarsky E.

Genes Dev. 2010 Mar 15;24(6):543-8. doi: 10.1101/gad.563110.

2.

A novel therapy of inducing hepatocyte hypertrophy by activating Akt/mTORC1 pathway in acute liver failure.

Wei T, Yu L, Lv Y.

Med Hypotheses. 2012 Jan;78(1):58-9. doi: 10.1016/j.mehy.2011.09.040. Epub 2011 Oct 17.

PMID:
22004987
3.

Vitamin D3 up-regulated protein 1 deficiency accelerates liver regeneration after partial hepatectomy in mice.

Kwon HJ, Won YS, Yoon YD, Yoon WK, Nam KH, Choi IP, Kim DY, Kim HC.

J Hepatol. 2011 Jun;54(6):1168-76. doi: 10.1016/j.jhep.2010.09.025. Epub 2010 Oct 26.

PMID:
21145821
4.

Reconstitution of liver mass via cellular hypertrophy in the rat.

Nagy P, Teramoto T, Factor VM, Sanchez A, Schnur J, Paku S, Thorgeirsson SS.

Hepatology. 2001 Feb;33(2):339-45.

PMID:
11172335
5.

Rejuvenation of aged progenitor cells by exposure to a young systemic environment.

Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA.

Nature. 2005 Feb 17;433(7027):760-4.

PMID:
15716955
6.
7.

IL-22 is involved in liver regeneration after hepatectomy.

Ren X, Hu B, Colletti LM.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G74-80. doi: 10.1152/ajpgi.00075.2009. Epub 2009 Oct 29.

8.

Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration.

Miyaoka Y, Ebato K, Kato H, Arakawa S, Shimizu S, Miyajima A.

Curr Biol. 2012 Jul 10;22(13):1166-75. doi: 10.1016/j.cub.2012.05.016. Epub 2012 May 31.

9.

Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration.

Rudnick DA, Perlmutter DH, Muglia LJ.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8885-90. Epub 2001 Jul 10.

10.

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.

Malato Y, Ehedego H, Al-Masaoudi M, Cubero FJ, Bornemann J, Gassler N, Liedtke C, Beraza N, Trautwein C.

Gastroenterology. 2012 Dec;143(6):1597-1608.e11. doi: 10.1053/j.gastro.2012.08.030. Epub 2012 Aug 23.

PMID:
22922425
11.

Serotonin reverts age-related capillarization and failure of regeneration in the liver through a VEGF-dependent pathway.

Furrer K, Rickenbacher A, Tian Y, Jochum W, Bittermann AG, Käch A, Humar B, Graf R, Moritz W, Clavien PA.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2945-50. doi: 10.1073/pnas.1012531108. Epub 2011 Jan 31.

12.

Impact of cell cycle disruption on impaired hepatic regeneration in aged livers with ischemic insult.

Suzuki A, Sakaguchi T, Inaba K, Suzuki S, Konno H.

J Surg Res. 2012 Apr;173(2):267-77. doi: 10.1016/j.jss.2010.10.012. Epub 2010 Nov 5.

PMID:
21109256
13.

Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection.

Bard-Chapeau EA, Yuan J, Droin N, Long S, Zhang EE, Nguyen TV, Feng GS.

Mol Cell Biol. 2006 Jun;26(12):4664-74.

14.

Loss of NF-kappaB activation in Kupffer cell-depleted mice impairs liver regeneration after partial hepatectomy.

Abshagen K, Eipel C, Kalff JC, Menger MD, Vollmar B.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1570-7. Epub 2007 Feb 22.

15.

Dehydroepiandrosterone causes hyperplasia and impairs regeneration in rat liver.

Kopplow K, Wayss K, Enzmann H, Mayer D.

Int J Oncol. 2005 Dec;27(6):1551-8.

PMID:
16273211
16.

Potential utility of xenobiotic mitogens in the context of liver regeneration in the elderly and living-related transplantation.

Columbano A, Simbula M, Pibiri M, Perra A, Pisanu A, Uccheddu A, Ledda-Columbano GM.

Lab Invest. 2008 Apr;88(4):408-15. doi: 10.1038/labinvest.2008.3. Epub 2008 Feb 11.

17.

Impaired proliferation of non-parenchymal cells participates in an impairment of liver regeneration in db/db mice.

Uetsuka K, Shirai M, Yamauchi H, Nakayama H, Doi K.

Exp Mol Pathol. 2005 Aug;79(1):51-8. Epub 2005 Apr 7.

PMID:
16005712
18.

Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: protection against apoptosis and retardation of hepatocyte proliferation.

Zeini M, Hortelano S, Través PG, Gómez-Valadés AG, Pujol A, Perales JC, Bartrons R, Boscá L.

FASEB J. 2005 Jun;19(8):995-7. Epub 2005 Mar 23.

PMID:
15788446
19.

Aging and liver regeneration.

Timchenko NA.

Trends Endocrinol Metab. 2009 May;20(4):171-6. doi: 10.1016/j.tem.2009.01.005. Epub 2009 Apr 7. Review.

PMID:
19359195
20.

Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes.

Nelsen CJ, Rickheim DG, Tucker MM, Hansen LK, Albrecht JH.

J Biol Chem. 2003 Feb 7;278(6):3656-63. Epub 2002 Nov 20.

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