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Items: 1 to 20 of 162

1.

Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.

Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7. doi: 10.1073/pnas.0909284107. Epub 2010 Mar 8.

2.

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain.

Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT.

Hum Mol Genet. 2009 Feb 1;18(3):391-404. doi: 10.1093/hmg/ddn361. Epub 2008 Nov 7.

PMID:
18996920
3.

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice.

Savonenko AV, Melnikova T, Laird FM, Stewart KA, Price DL, Wong PC.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5585-90. doi: 10.1073/pnas.0710373105. Epub 2008 Apr 2.

4.

Cleavage of neuregulin-1 by BACE1 or ADAM10 protein produces differential effects on myelination.

Luo X, Prior M, He W, Hu X, Tang X, Shen W, Yadav S, Kiryu-Seo S, Miller R, Trapp BD, Yan R.

J Biol Chem. 2011 Jul 8;286(27):23967-74. doi: 10.1074/jbc.M111.251538. Epub 2011 May 16.

5.

Structural Similarities between Neuregulin 1-3 Isoforms Determine Their Subcellular Distribution and Signaling Mode in Central Neurons.

Vullhorst D, Ahmad T, Karavanova I, Keating C, Buonanno A.

J Neurosci. 2017 May 24;37(21):5232-5249. doi: 10.1523/JNEUROSCI.2630-16.2017. Epub 2017 Apr 21.

PMID:
28432142
6.

The neuregulin-I/ErbB signaling system in development and disease.

Britsch S.

Adv Anat Embryol Cell Biol. 2007;190:1-65. Review.

PMID:
17432114
7.

Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels.

Deng QS, Dong XY, Wu H, Wang W, Wang ZT, Zhu JW, Liu CF, Jia WQ, Zhang Y, Schachner M, Ma QH, Xu RX.

Neuropsychopharmacology. 2016 Jan;41(2):440-53. doi: 10.1038/npp.2015.164. Epub 2015 Jun 11.

8.

Decreased Neuregulin 1 C-terminal fragment in Brodmann's area 6 of patients with schizophrenia.

Barakat A, Dean B, Scarr E, Evin G.

Schizophr Res. 2010 Dec;124(1-3):200-7. doi: 10.1016/j.schres.2010.09.001.

PMID:
20926259
9.

Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex.

Seshadri S, Faust T, Ishizuka K, Delevich K, Chung Y, Kim SH, Cowles M, Niwa M, Jaaro-Peled H, Tomoda T, Lai C, Anton ES, Li B, Sawa A.

Nat Commun. 2015 Dec 11;6:10118. doi: 10.1038/ncomms10118.

10.

Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.

Hu X, Fan Q, Hou H, Yan R.

J Neurochem. 2016 Jan;136(2):234-49. doi: 10.1111/jnc.13395. Epub 2015 Nov 13. Review.

11.

BACE1 dependent neuregulin processing: review.

Fleck D, Garratt AN, Haass C, Willem M.

Curr Alzheimer Res. 2012 Feb;9(2):178-83. Review.

PMID:
22455478
12.

Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitro.

Calaora V, Rogister B, Bismuth K, Murray K, Brandt H, Leprince P, Marchionni M, Dubois-Dalcq M.

J Neurosci. 2001 Jul 1;21(13):4740-51.

13.

Reversible overexpression of bace1-cleaved neuregulin-1 N-terminal fragment induces schizophrenia-like phenotypes in mice.

Luo X, He W, Hu X, Yan R.

Biol Psychiatry. 2014 Jul 15;76(2):120-7. doi: 10.1016/j.biopsych.2013.09.026. Epub 2013 Oct 5.

14.

In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.

Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.

J Pharmacol Exp Ther. 2008 Mar;324(3):957-69. Epub 2007 Dec 21.

15.

Calcyon stimulates neuregulin 1 maturation and signaling.

Yin DM, Chen YJ, Liu S, Jiao H, Shen C, Sathyamurthy A, Lin TW, Xiong WC, Li BM, Mei L, Bergson C.

Mol Psychiatry. 2015 Oct;20(10):1251-60. doi: 10.1038/mp.2014.131. Epub 2014 Oct 28.

PMID:
25349163
16.

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.

Hu X, He W, Diaconu C, Tang X, Kidd GJ, Macklin WB, Trapp BD, Yan R.

FASEB J. 2008 Aug;22(8):2970-80. doi: 10.1096/fj.08-106666. Epub 2008 Apr 15.

17.

Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.

Hu X, Schlanger R, He W, Macklin WB, Yan R.

FASEB J. 2013 May;27(5):1868-73. doi: 10.1096/fj.12-224212. Epub 2013 Jan 18.

18.

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.

Cheret C, Willem M, Fricker FR, Wende H, Wulf-Goldenberg A, Tahirovic S, Nave KA, Saftig P, Haass C, Garratt AN, Bennett DL, Birchmeier C.

EMBO J. 2013 Jul 17;32(14):2015-28. doi: 10.1038/emboj.2013.146. Epub 2013 Jun 21.

19.

Akt-mediated survival of oligodendrocytes induced by neuregulins.

Flores AI, Mallon BS, Matsui T, Ogawa W, Rosenzweig A, Okamoto T, Macklin WB.

J Neurosci. 2000 Oct 15;20(20):7622-30.

20.

Control of peripheral nerve myelination by the beta-secretase BACE1.

Willem M, Garratt AN, Novak B, Citron M, Kaufmann S, Rittger A, DeStrooper B, Saftig P, Birchmeier C, Haass C.

Science. 2006 Oct 27;314(5799):664-6. Epub 2006 Sep 21.

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