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Items: 1 to 20 of 167

1.

The role of parkin in familial and sporadic Parkinson's disease.

Dawson TM, Dawson VL.

Mov Disord. 2010;25 Suppl 1:S32-9. doi: 10.1002/mds.22798. Review.

2.

Parkin: much more than a simple ubiquitin ligase.

Alves da Costa C, Checler F.

Neurodegener Dis. 2012;10(1-4):49-51. doi: 10.1159/000332803. Epub 2011 Dec 23. Review.

PMID:
22204976
3.

Parkin-associated Parkinson's disease.

von Coelln R, Dawson VL, Dawson TM.

Cell Tissue Res. 2004 Oct;318(1):175-84. Epub 2004 Jul 30. Review.

PMID:
15503153
4.

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

Sriram SR, Li X, Ko HS, Chung KK, Wong E, Lim KL, Dawson VL, Dawson TM.

Hum Mol Genet. 2005 Sep 1;14(17):2571-86. Epub 2005 Jul 27.

PMID:
16049031
5.

The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson's disease.

Yasuda T, Mochizuki H.

Apoptosis. 2010 Nov;15(11):1312-21. doi: 10.1007/s10495-010-0486-8. Review.

PMID:
20221696
6.

Parkin and defective ubiquitination in Parkinson's disease.

Dawson TM.

J Neural Transm Suppl. 2006;(70):209-13. Review.

PMID:
17017531
7.

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.

Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, Iwatsubo T, Aebischer P.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17510-5. Epub 2004 Dec 2.

8.

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.

Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y, Dawson TM, Dawson VL.

Hum Mol Genet. 2005 Jan 1;14(1):71-84. Epub 2004 Nov 3.

PMID:
15525661
9.

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.

Yao D, Gu Z, Nakamura T, Shi ZQ, Ma Y, Gaston B, Palmer LA, Rockenstein EM, Zhang Z, Masliah E, Uehara T, Lipton SA.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10810-4. Epub 2004 Jul 13. Erratum in: Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13969.

10.

Parkin genetics: one model for Parkinson's disease.

Mata IF, Lockhart PJ, Farrer MJ.

Hum Mol Genet. 2004 Apr 1;13 Spec No 1:R127-33. Epub 2004 Feb 19. Review.

PMID:
14976155
11.

The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.

Pickrell AM, Youle RJ.

Neuron. 2015 Jan 21;85(2):257-73. doi: 10.1016/j.neuron.2014.12.007. Review.

12.

New insights into Parkinson's disease.

Chung KK, Dawson VL, Dawson TM.

J Neurol. 2003 Oct;250 Suppl 3:III15-24. Review.

PMID:
14579120
13.

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology?

Truban D, Hou X, Caulfield TR, Fiesel FC, Springer W.

J Parkinsons Dis. 2017;7(1):13-29. doi: 10.3233/JPD-160989. Review.

14.

Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin.

Im E, Yoo L, Hyun M, Shin WH, Chung KC.

Open Biol. 2016 Aug;6(8). pii: 160193. doi: 10.1098/rsob.160193.

15.

AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease.

Haskin J, Szargel R, Shani V, Mekies LN, Rott R, Lim GG, Lim KL, Bandopadhyay R, Wolosker H, Engelender S.

Hum Mol Genet. 2013 May 15;22(10):2083-96. doi: 10.1093/hmg/ddt058. Epub 2013 Feb 7.

16.

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.

Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16691-6. doi: 10.1073/pnas.1006083107. Epub 2010 Sep 7.

17.

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity.

Hampe C, Ardila-Osorio H, Fournier M, Brice A, Corti O.

Hum Mol Genet. 2006 Jul 1;15(13):2059-75. Epub 2006 May 19.

PMID:
16714300
18.

How do Parkin mutations result in neurodegeneration?

Imai Y, Takahashi R.

Curr Opin Neurobiol. 2004 Jun;14(3):384-9. Review.

PMID:
15194120
19.

Activation of the E3 ubiquitin ligase Parkin.

Caulfield TR, Fiesel FC, Springer W.

Biochem Soc Trans. 2015 Apr;43(2):269-74. doi: 10.1042/BST20140321. Review.

20.

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease.

Dodson MW, Guo M.

Curr Opin Neurobiol. 2007 Jun;17(3):331-7. Epub 2007 May 11. Review.

PMID:
17499497

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