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Items: 1 to 20 of 91

1.

Dictyostelium differentiation-inducing factor-1 binds to mitochondrial malate dehydrogenase and inhibits its activity.

Matsuda T, Takahashi-Yanaga F, Yoshihara T, Maenaka K, Watanabe Y, Miwa Y, Morimoto S, Kubohara Y, Hirata M, Sasaguri T.

J Pharmacol Sci. 2010;112(3):320-6. Epub 2010 Feb 20.

2.

Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.

Matsuzaki E, Takahashi-Yanaga F, Miwa Y, Hirata M, Watanabe Y, Sato N, Morimoto S, Hirofuji T, Maeda K, Sasaguri T.

J Bone Miner Res. 2006 Aug;21(8):1307-16.

3.
4.

Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/β-catenin signaling pathway.

Yoshihara T, Takahashi-Yanaga F, Shiraishi F, Morimoto S, Watanabe Y, Hirata M, Hoka S, Sasaguri T.

Mol Cancer. 2010 Sep 16;9:245. doi: 10.1186/1476-4598-9-245.

5.

DIF-1 inhibits the Wnt/β-catenin signaling pathway by inhibiting TCF7L2 expression in colon cancer cell lines.

Jingushi K, Takahashi-Yanaga F, Yoshihara T, Shiraishi F, Watanabe Y, Hirata M, Morimoto S, Sasaguri T.

Biochem Pharmacol. 2012 Jan 1;83(1):47-56. doi: 10.1016/j.bcp.2011.10.001. Epub 2011 Oct 8.

PMID:
22005519
6.

Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells.

Omata W, Shibata H, Nagasawa M, Kojima I, Kikuchi H, Oshima Y, Hosaka K, Kubohara Y.

FEBS J. 2007 Jul;274(13):3392-404. Epub 2007 Jun 6.

7.

Differentiation-inducing factor-1 and -2 function also as modulators for Dictyostelium chemotaxis.

Kuwayama H, Kubohara Y.

PLoS One. 2009 Aug 17;4(8):e6658. doi: 10.1371/journal.pone.0006658.

8.

Differentiation-inducing factor-1 suppresses the expression of c-Myc in the human cancer cell lines.

Jingushi K, Nakamura T, Takahashi-Yanaga F, Matsuzaki E, Watanabe Y, Yoshihara T, Morimoto S, Sasaguri T.

J Pharmacol Sci. 2013;121(2):103-9. Epub 2013 Jan 25.

9.

Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway.

Kanai M, Konda Y, Nakajima T, Izumi Y, Kanda N, Nanakin A, Kubohara Y, Chiba T.

Oncogene. 2003 Jan 30;22(4):548-54.

PMID:
12555068
11.
12.

Exploitation of the derivatives of Dictyostelium differentiation-inducing factor-1, which promote glucose consumption in mammalian cells.

Kubohara Y, Kikuchi H, Oshima Y.

Life Sci. 2008 Oct 24;83(17-18):608-12. doi: 10.1016/j.lfs.2008.08.012. Epub 2008 Sep 9.

PMID:
18812178
13.

Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration and invasion.

Arioka M, Takahashi-Yanaga F, Kubo M, Igawa K, Tomooka K, Sasaguri T.

Biochem Pharmacol. 2017 Aug 15;138:31-48. doi: 10.1016/j.bcp.2017.05.004. Epub 2017 May 10.

PMID:
28501501
14.

Mitochondria are the target organelle of differentiation-inducing factor-3, an anti-tumor agent isolated from Dictyostelium discoideum [corrected].

Kubohara Y, Kikuchi H, Matsuo Y, Oshima Y, Homma Y.

PLoS One. 2013 Aug 15;8(8):e72118. doi: 10.1371/journal.pone.0072118. eCollection 2013. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/7a1f1670-ee25-436a-867c-3d5e160ac6cb.

15.

Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium.

Kikuchi H, Ishiko S, Oshima Y, Gokan N, Hosaka K, Kubohara Y.

Biochem Biophys Res Commun. 2008 Dec 19;377(3):1012-7. doi: 10.1016/j.bbrc.2008.10.105. Epub 2008 Oct 31.

PMID:
18977198
16.

New roles for DIF? Effects on early development in Dictyostelium.

Wurster B, Kay RR.

Dev Biol. 1990 Jul;140(1):189-95.

PMID:
2162792
17.

Derivatives of Dictyostelium differentiation-inducing factors promote mitogen-activated IL-2 production via AP-1 in Jurkat cells.

Takahashi K, Murakami M, Kikuchi H, Oshima Y, Kubohara Y.

Life Sci. 2011 Mar 14;88(11-12):480-5. doi: 10.1016/j.lfs.2011.01.004. Epub 2011 Jan 14.

PMID:
21238462
18.

Autophagic or necrotic cell death triggered by distinct motifs of the differentiation factor DIF-1.

Luciani MF, Kubohara Y, Kikuchi H, Oshima Y, Golstein P.

Cell Death Differ. 2009 Apr;16(4):564-70. doi: 10.1038/cdd.2008.177. Epub 2008 Dec 12.

19.

Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo.

Kubokura N, Takahashi-Yanaga F, Arioka M, Yoshihara T, Igawa K, Tomooka K, Morimoto S, Nakatsu Y, Tsuzuki T, Nakabeppu Y, Matsumoto T, Kitazono T, Sasaguri T.

J Pharmacol Sci. 2015 Apr;127(4):446-55. doi: 10.1016/j.jphs.2015.03.005. Epub 2015 Mar 24.

20.

Differentiation-inducing factor-1 suppresses gene expression of cyclin D1 in tumor cells.

Yasmin T, Takahashi-Yanaga F, Mori J, Miwa Y, Hirata M, Watanabe Y, Morimoto S, Sasaguri T.

Biochem Biophys Res Commun. 2005 Dec 16;338(2):903-9. Epub 2005 Oct 14.

PMID:
16243295

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