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Items: 1 to 20 of 88

1.

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication.

Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, Domené S, Vélez JI, Karkera JD, Balog J, Berg K, Kleta R, Gahl WA, Roessler E, Long R, Lie J, Pineda D, Londoño AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Johansson S, Knappskog PM, Haavik J, Ribases M, Cormand B, Bayes M, Casas M, Ramos-Quiroga JA, Hervas A, Maher BS, Faraone SV, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Swanson J, Vortmeyer A, Bailey-Wilson JE, Castellanos FX, Muenke M.

Mol Psychiatry. 2010 Nov;15(11):1053-66. doi: 10.1038/mp.2010.6. Epub 2010 Feb 16.

2.

LPHN3 and attention-deficit/hyperactivity disorder: a susceptibility and pharmacogenetic study.

Bruxel EM, Salatino-Oliveira A, Akutagava-Martins GC, Tovo-Rodrigues L, Genro JP, Zeni CP, Polanczyk GV, Chazan R, Schmitz M, Arcos-Burgos M, Rohde LA, Hutz MH.

Genes Brain Behav. 2015 Jun;14(5):419-27. doi: 10.1111/gbb.12224.

3.

Contribution of LPHN3 to the genetic susceptibility to ADHD in adulthood: a replication study.

Ribasés M, Ramos-Quiroga JA, Sánchez-Mora C, Bosch R, Richarte V, Palomar G, Gastaminza X, Bielsa A, Arcos-Burgos M, Muenke M, Castellanos FX, Cormand B, Bayés M, Casas M.

Genes Brain Behav. 2011 Mar;10(2):149-57. doi: 10.1111/j.1601-183X.2010.00649.x. Epub 2010 Nov 4.

4.

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD.

Jain M, Vélez JI, Acosta MT, Palacio LG, Balog J, Roessler E, Pineda D, Londoño AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Swanson J, Castellanos FX, Bailey-Wilson JE, Arcos-Burgos M, Muenke M.

Mol Psychiatry. 2012 Jul;17(7):741-7. doi: 10.1038/mp.2011.59. Epub 2011 May 24.

5.

An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility.

Martinez AF, Abe Y, Hong S, Molyneux K, Yarnell D, Löhr H, Driever W, Acosta MT, Arcos-Burgos M, Muenke M.

Biol Psychiatry. 2016 Dec 15;80(12):943-954. doi: 10.1016/j.biopsych.2016.06.026. Epub 2016 Jul 14.

PMID:
27692237
6.

Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility.

Domené S, Stanescu H, Wallis D, Tinloy B, Pineda DE, Kleta R, Arcos-Burgos M, Roessler E, Muenke M.

Am J Med Genet B Neuropsychiatr Genet. 2011 Jan;156B(1):11-8. doi: 10.1002/ajmg.b.31141. Epub 2010 Nov 12.

PMID:
21184580
7.

LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy.

Choudhry Z, Sengupta SM, Grizenko N, Fortier ME, Thakur GA, Bellingham J, Joober R.

J Child Psychol Psychiatry. 2012 Aug;53(8):892-902. doi: 10.1111/j.1469-7610.2012.02551.x. Epub 2012 Apr 7.

PMID:
22486528
8.

Refining psychiatric phenotypes for response to treatment: contribution of LPHN3 in ADHD.

Labbe A, Liu A, Atherton J, Gizenko N, Fortier MÈ, Sengupta SM, Ridha J.

Am J Med Genet B Neuropsychiatr Genet. 2012 Oct;159B(7):776-85. doi: 10.1002/ajmg.b.32083. Epub 2012 Jul 31.

PMID:
22851411
9.

Association of LPHN3 rs6551665 A/G polymorphism with attention deficit and hyperactivity disorder in Korean children.

Hwang IW, Lim MH, Kwon HJ, Jin HJ.

Gene. 2015 Jul 15;566(1):68-73. doi: 10.1016/j.gene.2015.04.033. Epub 2015 Apr 12.

PMID:
25871512
10.

Association of SNAP-25, SLC6A2, and LPHN3 with OROS methylphenidate treatment response in attention-deficit/hyperactivity disorder.

Song J, Kim SW, Hong HJ, Lee MG, Lee BW, Choi TK, Lee SH, Yook KH.

Clin Neuropharmacol. 2014 Sep-Oct;37(5):136-41. doi: 10.1097/WNF.0000000000000045.

PMID:
25229170
11.

Influence of a latrophilin 3 (LPHN3) risk haplotype on event-related potential measures of cognitive response control in attention-deficit hyperactivity disorder (ADHD).

Fallgatter AJ, Ehlis AC, Dresler T, Reif A, Jacob CP, Arcos-Burgos M, Muenke M, Lesch KP.

Eur Neuropsychopharmacol. 2013 Jun;23(6):458-68. doi: 10.1016/j.euroneuro.2012.11.001. Epub 2012 Dec 12.

12.

Toward a better understanding of ADHD: LPHN3 gene variants and the susceptibility to develop ADHD.

Arcos-Burgos M, Muenke M.

Atten Defic Hyperact Disord. 2010 Nov;2(3):139-47. doi: 10.1007/s12402-010-0030-2. Epub 2010 Oct 16. Review.

13.

The ADHD-susceptibility gene lphn3.1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development.

Lange M, Norton W, Coolen M, Chaminade M, Merker S, Proft F, Schmitt A, Vernier P, Lesch KP, Bally-Cuif L.

Mol Psychiatry. 2012 Sep;17(9):946-54. doi: 10.1038/mp.2012.29. Epub 2012 Apr 17.

PMID:
22508465
14.

The genetics of attention deficit/hyperactivity disorder in adults, a review.

Franke B, Faraone SV, Asherson P, Buitelaar J, Bau CH, Ramos-Quiroga JA, Mick E, Grevet EH, Johansson S, Haavik J, Lesch KP, Cormand B, Reif A; International Multicentre persistent ADHD CollaboraTion.

Mol Psychiatry. 2012 Oct;17(10):960-87. doi: 10.1038/mp.2011.138. Epub 2011 Nov 22. Review.

15.

Spatial attentional bias as a marker of genetic risk, symptom severity, and stimulant response in ADHD.

Bellgrove MA, Barry E, Johnson KA, Cox M, Dáibhis A, Daly M, Hawi Z, Lambert D, Fitzgerald M, McNicholas F, Robertson IH, Gill M, Kirley A.

Neuropsychopharmacology. 2008 Sep;33(10):2536-45. Epub 2007 Nov 28.

16.

Dense-map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36.

Field LL, Shumansky K, Ryan J, Truong D, Swiergala E, Kaplan BJ.

Genes Brain Behav. 2013 Feb;12(1):56-69. doi: 10.1111/gbb.12003. Epub 2012 Dec 7.

17.

Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.

Wallis D, Hill DS, Mendez IA, Abbott LC, Finnell RH, Wellman PJ, Setlow B.

Brain Res. 2012 Jun 29;1463:85-92. doi: 10.1016/j.brainres.2012.04.053. Epub 2012 May 7.

PMID:
22575564
18.

A two-locus genetic interaction between LPHN3 and 11q predicts ADHD severity and long-term outcome.

Acosta MT, Vélez JI, Bustamante ML, Balog JZ, Arcos-Burgos M, Muenke M.

Transl Psychiatry. 2011 Jul 5;1:e17. doi: 10.1038/tp.2011.14.

19.

Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children.

Gomez-Sanchez CI, Riveiro-Alvarez R, Soto-Insuga V, Rodrigo M, Tirado-Requero P, Mahillo-Fernandez I, Abad-Santos F, Carballo JJ, Dal-Ré R, Ayuso C.

Behav Brain Funct. 2016 Jan 8;12(1):2. doi: 10.1186/s12993-015-0084-6.

20.

Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis.

Swanson JM, Kinsbourne M, Nigg J, Lanphear B, Stefanatos GA, Volkow N, Taylor E, Casey BJ, Castellanos FX, Wadhwa PD.

Neuropsychol Rev. 2007 Mar;17(1):39-59. Review.

PMID:
17318414

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