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A mineral-rich red algae extract inhibits polyp formation and inflammation in the gastrointestinal tract of mice on a high-fat diet.

Aslam MN, Paruchuri T, Bhagavathula N, Varani J.

Integr Cancer Ther. 2010 Mar;9(1):93-9. doi: 10.1177/1534735409360360. Epub 2010 Feb 11.


A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.

Aslam MN, Kreider JM, Paruchuri T, Bhagavathula N, DaSilva M, Zernicke RF, Goldstein SA, Varani J.

Calcif Tissue Int. 2010 Apr;86(4):313-24. doi: 10.1007/s00223-010-9340-9. Epub 2010 Feb 24.


A multimineral natural product from red marine algae reduces colon polyp formation in C57BL/6 mice.

Aslam MN, Bergin I, Naik M, Paruchuri T, Hampton A, Rehman M, Dame MK, Rush H, Varani J.

Nutr Cancer. 2012;64(7):1020-8. doi: 10.1080/01635581.2012.713160. Epub 2012 Oct 4.


A multi-mineral natural product inhibits liver tumor formation in C57BL/6 mice.

Aslam MN, Bergin I, Naik M, Hampton A, Allen R, Kunkel SL, Rush H, Varani J.

Biol Trace Elem Res. 2012 Jun;147(1-3):267-74. doi: 10.1007/s12011-011-9316-2. Epub 2012 Jan 6.


Ulcerative Dermatitis in C57BL/6NCrl Mice on a Low-Fat or High-Fat Diet With or Without a Mineralized Red-Algae Supplement.

Hampton AL, Aslam MN, Naik MK, Bergin IL, Allen RM, Craig RA, Kunkel SL, Veerapaneni I, Paruchuri T, Patterson KA, Rothman ED, Hish GA, Varani J, Rush HG.

J Am Assoc Lab Anim Sci. 2015 Sep;54(5):487-96.


Preservation of bone structure and function by Lithothamnion sp. derived minerals.

Aslam MN, Bergin I, Jepsen K, Kreider JM, Graf KH, Naik M, Goldstein SA, Varani J.

Biol Trace Elem Res. 2013 Dec;156(1-3):210-20. doi: 10.1007/s12011-013-9820-7. Epub 2013 Oct 6.


Human colon tissue in organ culture: calcium and multi-mineral-induced mucosal differentiation.

Dame MK, Veerapaneni I, Bhagavathula N, Naik M, Varani J.

In Vitro Cell Dev Biol Anim. 2011 Jan;47(1):32-8. doi: 10.1007/s11626-010-9358-3. Epub 2010 Nov 20.


Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice.

Hioki K, Shivapurkar N, Oshima H, Alabaster O, Oshima M, Taketo MM.

Carcinogenesis. 1997 Oct;18(10):1863-5.


The interaction of a high-fat diet and regular moderate intensity exercise on intestinal polyp development in Apc Min/+ mice.

Baltgalvis KA, Berger FG, Peña MM, Davis JM, Carson JA.

Cancer Prev Res (Phila). 2009 Jul;2(7):641-9. doi: 10.1158/1940-6207.CAPR-09-0017. Epub 2009 Jun 23.


Growth-inhibitory effects of a mineralized extract from the red marine algae, Lithothamnion calcareum, on Ca(2+)-sensitive and Ca(2+)-resistant human colon carcinoma cells.

Aslam MN, Bhagavathula N, Paruchuri T, Hu X, Chakrabarty S, Varani J.

Cancer Lett. 2009 Oct 8;283(2):186-92. doi: 10.1016/j.canlet.2009.03.037. Epub 2009 Apr 24.


A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner.

Aviello G, Amu S, Saunders SP, Fallon PG.

Phytother Res. 2014 Feb;28(2):300-4. doi: 10.1002/ptr.4989. Epub 2013 Apr 4.


Effects of dietary fat and a vegetable-fruit mixture on the development of intestinal neoplasia in the ApcMin mouse.

van Kranen HJ, van Iersel PW, Rijnkels JM, Beems DB, Alink GM, van Kreijl CF.

Carcinogenesis. 1998 Sep;19(9):1597-601.


Evaluation of calcium supplementation with algae (Lithothamnion muelleri) on metabolic and inflammatory parameters in mice fed a high refined carbohydrate-containing diet.

Menezes-Garcia Z, Santiago AF, Faria AM, Oliveira MC, Botion LM, Souza DG, Teixeira MM, Ferreira AV.

Int J Food Sci Nutr. 2014 Jun;65(4):489-94. doi: 10.3109/09637486.2013.879287. Epub 2014 Jan 23.


Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse.

Song J, Medline A, Mason JB, Gallinger S, Kim YI.

Cancer Res. 2000 Oct 1;60(19):5434-40.


Chemoprevention of intestinal polyps in ApcMin/+ mice fed with western or balanced diets by drinking annurca apple polyphenol extract.

Fini L, Piazzi G, Daoud Y, Selgrad M, Maegawa S, Garcia M, Fogliano V, Romano M, Graziani G, Vitaglione P, Carmack SW, Gasbarrini A, Genta RM, Issa JP, Boland CR, Ricciardiello L.

Cancer Prev Res (Phila). 2011 Jun;4(6):907-15. doi: 10.1158/1940-6207.CAPR-10-0359. Epub 2011 Mar 7.


Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets.

Reddy BS, Rivenson A, El-Bayoumy K, Upadhyaya P, Pittman B, Rao CV.

J Natl Cancer Inst. 1997 Apr 2;89(7):506-12.


A mineral and antioxidant-rich extract from the red marine Algae Alsidium corallinum exhibits cytoprotective effects against potassium bromate-induced erythrocyte oxidative damages in mice.

Ben Saad H, Nasri I, Elwej A, Krayem N, Jarraya R, Kallel C, Zeghal N, Amara IB.

Biol Trace Elem Res. 2014 Jul;160(1):85-96. doi: 10.1007/s12011-014-0025-5. Epub 2014 Jun 10.


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