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Items: 1 to 20 of 149


Mical links semaphorins to F-actin disassembly.

Hung RJ, Yazdani U, Yoon J, Wu H, Yang T, Gupta N, Huang Z, van Berkel WJ, Terman JR.

Nature. 2010 Feb 11;463(7282):823-7. doi: 10.1038/nature08724.


Extracellular inhibitors, repellents, and semaphorin/plexin/MICAL-mediated actin filament disassembly.

Hung RJ, Terman JR.

Cytoskeleton (Hoboken). 2011 Aug;68(8):415-33. doi: 10.1002/cm.20527. Epub 2011 Aug 25. Review.


Direct redox regulation of F-actin assembly and disassembly by Mical.

Hung RJ, Pak CW, Terman JR.

Science. 2011 Dec 23;334(6063):1710-3. doi: 10.1126/science.1211956. Epub 2011 Nov 24.


MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.

Terman JR, Mao T, Pasterkamp RJ, Yu HH, Kolodkin AL.

Cell. 2002 Jun 28;109(7):887-900.


Differential regulation of actin microfilaments by human MICAL proteins.

Giridharan SS, Rohn JL, Naslavsky N, Caplan S.

J Cell Sci. 2012 Feb 1;125(Pt 3):614-24. doi: 10.1242/jcs.089367. Epub 2012 Feb 13.


SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics.

Hung RJ, Spaeth CS, Yesilyurt HG, Terman JR.

Nat Cell Biol. 2013 Dec;15(12):1445-54. doi: 10.1038/ncb2871. Epub 2013 Nov 10.


Release of MICAL autoinhibition by semaphorin-plexin signaling promotes interaction with collapsin response mediator protein.

Schmidt EF, Shim SO, Strittmatter SM.

J Neurosci. 2008 Feb 27;28(9):2287-97. doi: 10.1523/JNEUROSCI.5646-07.2008.


A simple and efficient method for generating high-quality recombinant Mical enzyme for in vitro assays.

Wu H, Hung RJ, Terman JR.

Protein Expr Purif. 2016 Nov;127:116-24. doi: 10.1016/j.pep.2016.05.008. Epub 2016 May 17.


Semaphorins: green light for redox signaling?

Ventura A, Pelicci PG.

Sci STKE. 2002 Oct 22;2002(155):pe44. Review.


Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho.

Driessens MH, Hu H, Nobes CD, Self A, Jordens I, Goodman CS, Hall A.

Curr Biol. 2001 Mar 6;11(5):339-44.


Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin.

Tasaka G, Negishi M, Oinuma I.

J Neurosci. 2012 Jun 13;32(24):8293-305. doi: 10.1523/JNEUROSCI.0799-12.2012.


Neuronal guidance: a redox signal involving Mical.

Bernstein BW, Bamburg JR.

Curr Biol. 2010 Apr 27;20(8):R360-2. doi: 10.1016/j.cub.2010.03.008.


Plexin A is a neuronal semaphorin receptor that controls axon guidance.

Winberg ML, Noordermeer JN, Tamagnone L, Comoglio PM, Spriggs MK, Tessier-Lavigne M, Goodman CS.

Cell. 1998 Dec 23;95(7):903-16.


F-actin dismantling through a redox-driven synergy between Mical and cofilin.

Grintsevich EE, Yesilyurt HG, Rich SK, Hung RJ, Terman JR, Reisler E.

Nat Cell Biol. 2016 Aug;18(8):876-85. doi: 10.1038/ncb3390. Epub 2016 Jul 25.


Regulating small G protein signaling to coordinate axon adhesion and repulsion.

Yang T, Terman JR.

Small GTPases. 2013 Jan-Mar;4(1):34-41. doi: 10.4161/sgtp.22765. Epub 2012 Dec 17.


Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B.

Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS.

Cancer Res. 2004 Aug 1;64(15):5212-24.


Drosophila Plexin B is a Sema-2a receptor required for axon guidance.

Ayoob JC, Terman JR, Kolodkin AL.

Development. 2006 Jun;133(11):2125-35. Epub 2006 May 3.


Characterizing F-actin Disassembly Induced by the Semaphorin-Signaling Component MICAL.

Yoon J, Hung RJ, Terman JR.

Methods Mol Biol. 2017;1493:119-128.


The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.

Van Battum EY, Gunput RA, Lemstra S, Groen EJ, Yu KL, Adolfs Y, Zhou Y, Hoogenraad CC, Yoshida Y, Schachner M, Akhmanova A, Pasterkamp RJ.

Nat Commun. 2014 Jul 10;5:4317. doi: 10.1038/ncomms5317.


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