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Items: 1 to 20 of 109

1.

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.

Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN; Cancer Genome Atlas Research Network.

Cancer Cell. 2010 Jan 19;17(1):98-110. doi: 10.1016/j.ccr.2009.12.020.

2.

A simplified approach for molecular classification of glioblastomas (GBMs): experience from a tertiary care center in India.

Purkait S, Mallick S, Sharma V, Kumar A, Pathak P, Jha P, Biswas A, Julka PK, Gupta D, Suri A, Upadhyay AD, Suri V, Sharma MC, Sarkar C.

Brain Tumor Pathol. 2016 Jul;33(3):183-90. doi: 10.1007/s10014-016-0251-y. Epub 2016 Feb 10.

PMID:
26865311
3.

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.

Reifenberger G, Weber RG, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel MC, Gramatzki D, Felsberg J, Hartmann C, Steinbach JP, Schlegel U, Wick W, Radlwimmer B, Pietsch T, Tonn JC, von Deimling A, Binder H, Weller M, Loeffler M; German Glioma Network.

Int J Cancer. 2014 Oct 15;135(8):1822-31. doi: 10.1002/ijc.28836. Epub 2014 Mar 28.

4.

Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups.

Hinrichs BH, Newman S, Appin CL, Dunn W, Cooper L, Pauly R, Kowalski J, Rossi MR, Brat DJ.

Acta Neuropathol Commun. 2016 Jan 13;4:4. doi: 10.1186/s40478-015-0270-7.

5.

Molecular subtypes of glioblastoma are relevant to lower grade glioma.

Guan X, Vengoechea J, Zheng S, Sloan AE, Chen Y, Brat DJ, O'Neill BP, de Groot J, Yust-Katz S, Yung WK, Cohen ML, Aldape KD, Rosenfeld S, Verhaak RG, Barnholtz-Sloan JS.

PLoS One. 2014 Mar 10;9(3):e91216. doi: 10.1371/journal.pone.0091216. eCollection 2014.

6.

PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma.

Phillips JJ, Aranda D, Ellison DW, Judkins AR, Croul SE, Brat DJ, Ligon KL, Horbinski C, Venneti S, Zadeh G, Santi M, Zhou S, Appin CL, Sioletic S, Sullivan LM, Martinez-Lage M, Robinson AE, Yong WH, Cloughesy T, Lai A, Phillips HS, Marshall R, Mueller S, Haas-Kogan DA, Molinaro AM, Perry A.

Brain Pathol. 2013 Sep;23(5):565-73. doi: 10.1111/bpa.12043. Epub 2013 Mar 18.

7.

Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics.

Li R, Chen X, You Y, Wang X, Liu Y, Hu Q, Yan W.

Oncotarget. 2015 Oct 13;6(31):30968-74. doi: 10.18632/oncotarget.5038.

8.

Unique genome-wide map of TCF4 and STAT3 targets using ChIP-seq reveals their association with new molecular subtypes of glioblastoma.

Zhang JX, Zhang J, Yan W, Wang YY, Han L, Yue X, Liu N, You YP, Jiang T, Pu PY, Kang CS.

Neuro Oncol. 2013 Mar;15(3):279-89. doi: 10.1093/neuonc/nos306. Epub 2013 Jan 7.

9.

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome.

Favero F, McGranahan N, Salm M, Birkbak NJ, Sanborn JZ, Benz SC, Becq J, Peden JF, Kingsbury Z, Grocok RJ, Humphray S, Bentley D, Spencer-Dene B, Gutteridge A, Brada M, Roger S, Dietrich PY, Forshew T, Gerlinger M, Rowan A, Stamp G, Eklund AC, Szallasi Z, Swanton C.

Ann Oncol. 2015 May;26(5):880-7. doi: 10.1093/annonc/mdv127. Epub 2015 Mar 2.

10.

Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development.

Brown KE, Chagoya G, Kwatra SG, Yen T, Keir ST, Cooter M, Hoadley KA, Rasheed A, Lipp ES, Mclendon R, Ali-Osman F, Bigner DD, Sampson JH, Kwatra MM.

J Neurochem. 2015 Jun;133(5):730-8. doi: 10.1111/jnc.13032. Epub 2015 Feb 12.

11.

Transcriptional diversity of long-term glioblastoma survivors.

Gerber NK, Goenka A, Turcan S, Reyngold M, Makarov V, Kannan K, Beal K, Omuro A, Yamada Y, Gutin P, Brennan CW, Huse JT, Chan TA.

Neuro Oncol. 2014 Sep;16(9):1186-95. doi: 10.1093/neuonc/nou043. Epub 2014 Mar 23.

12.

A simplified approach for the molecular classification of glioblastomas.

Le Mercier M, Hastir D, Moles Lopez X, De Nève N, Maris C, Trepant AL, Rorive S, Decaestecker C, Salmon I.

PLoS One. 2012;7(9):e45475. doi: 10.1371/journal.pone.0045475. Epub 2012 Sep 18.

13.

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM.

Cancer Cell. 2012 Oct 16;22(4):425-37. doi: 10.1016/j.ccr.2012.08.024.

14.

Detection of p53 mutations in proliferating vascular cells in glioblastoma multiforme.

Kawasoe T, Takeshima H, Yamashita S, Mizuguchi S, Fukushima T, Yokogami K, Yamasaki K.

J Neurosurg. 2015 Feb;122(2):317-23. doi: 10.3171/2014.10.JNS132159. Epub 2014 Nov 21.

PMID:
25415071
15.

An integrated genomic analysis of human glioblastoma multiforme.

Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA Jr, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW.

Science. 2008 Sep 26;321(5897):1807-12. doi: 10.1126/science.1164382. Epub 2008 Sep 4.

16.

Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma.

Liu Q, Liu Y, Li W, Wang X, Sawaya R, Lang FF, Yung WK, Chen K, Fuller GN, Zhang W.

Acta Neuropathol. 2015 Oct;130(4):587-97. doi: 10.1007/s00401-015-1470-8. Epub 2015 Sep 1.

17.

Characterization of molecular genetic alterations in GBMs highlights a distinctive molecular profile in young adults.

Jha P, Suri V, Singh G, Jha P, Purkait S, Pathak P, Sharma V, Sharma MC, Suri A, Gupta D, Mahapatra AK, Sarkar C.

Diagn Mol Pathol. 2011 Dec;20(4):225-32. doi: 10.1097/PDM.0b013e31821c30bc.

PMID:
22089350
18.

An integrative characterization of recurrent molecular aberrations in glioblastoma genomes.

Sintupisut N, Liu PL, Yeang CH.

Nucleic Acids Res. 2013 Oct;41(19):8803-21. doi: 10.1093/nar/gkt656. Epub 2013 Jul 31.

19.

Genomic estimates of aneuploid content in glioblastoma multiforme and improved classification.

Li B, Senbabaoglu Y, Peng W, Yang ML, Xu J, Li JZ.

Clin Cancer Res. 2012 Oct 15;18(20):5595-605. doi: 10.1158/1078-0432.CCR-12-1427. Epub 2012 Aug 21. Erratum in: Clin Cancer Res. 2014 May 1;20(9):2500.

20.

Identification of molecular subtypes of glioblastoma by gene expression profiling.

Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM, Cloughesy TF, Nelson SF.

Oncogene. 2003 Apr 17;22(15):2361-73.

PMID:
12700671

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