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Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis.

Nakatomi M, Wang XP, Key D, Lund JJ, Turbe-Doan A, Kist R, Aw A, Chen Y, Maas RL, Peters H.

Dev Biol. 2010 Apr 15;340(2):438-49. doi: 10.1016/j.ydbio.2010.01.031. Epub 2010 Feb 1.


Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field.

Zhou J, Gao Y, Zhang Z, Zhang Y, Maltby KM, Liu Z, Lan Y, Jiang R.

Dev Biol. 2011 May 15;353(2):344-53. doi: 10.1016/j.ydbio.2011.03.012. Epub 2011 Mar 17.


Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development.

Ogawa T, Kapadia H, Feng JQ, Raghow R, Peters H, D'Souza RN.

J Biol Chem. 2006 Jul 7;281(27):18363-9. Epub 2006 May 1.


Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis.

Zhou J, Gao Y, Lan Y, Jia S, Jiang R.

Development. 2013 Dec;140(23):4709-18. doi: 10.1242/dev.099028. Epub 2013 Oct 30.


Genes affecting tooth morphogenesis.

Kapadia H, Mues G, D'Souza R.

Orthod Craniofac Res. 2007 Aug;10(3):105-13. Review. Erratum in: Orthod Craniofac Res. 2007 Nov;10(4):236. Corrected and republished in: Orthod Craniofac Res. 2007 Nov;10(4):237-44.


Deletion of Osr2 Partially Rescues Tooth Development in Runx2 Mutant Mice.

Kwon HJ, Park EK, Jia S, Liu H, Lan Y, Jiang R.

J Dent Res. 2015 Aug;94(8):1113-9. doi: 10.1177/0022034515583673. Epub 2015 Apr 27.


Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development.

Saadi I, Das P, Zhao M, Raj L, Ruspita I, Xia Y, Papaioannou VE, Bei M.

Development. 2013 Jul;140(13):2697-702. doi: 10.1242/dev.088393. Epub 2013 May 29.


Genes affecting tooth morphogenesis.

Kapadia H, Mues G, D'Souza R.

Orthod Craniofac Res. 2007 Nov;10(4):237-44. Review.


Roles of Bmp4 during tooth morphogenesis and sequential tooth formation.

Jia S, Zhou J, Gao Y, Baek JA, Martin JF, Lan Y, Jiang R.

Development. 2013 Jan 15;140(2):423-32. doi: 10.1242/dev.081927.


Msx1 mutations: how do they cause tooth agenesis?

Wang Y, Kong H, Mues G, D'Souza R.

J Dent Res. 2011 Mar;90(3):311-6. doi: 10.1177/0022034510387430.


Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis.

Aberg T, Wang XP, Kim JH, Yamashiro T, Bei M, Rice R, Ryoo HM, Thesleff I.

Dev Biol. 2004 Jun 1;270(1):76-93.


Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia.

Kist R, Watson M, Wang X, Cairns P, Miles C, Reid DJ, Peters H.

Hum Mol Genet. 2005 Dec 1;14(23):3605-17. Epub 2005 Oct 19.


A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ.

Zhang Y, Zhang Z, Zhao X, Yu X, Hu Y, Geronimo B, Fromm SH, Chen YP.

Development. 2000 Apr;127(7):1431-43.


BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development.

Bei M, Kratochwil K, Maas RL.

Development. 2000 Nov;127(21):4711-8.


Differentiation of Odontoblast-Like Cells From Mouse Induced Pluripotent Stem Cells by Pax9 and Bmp4 Transfection.

Seki D, Takeshita N, Oyanagi T, Sasaki S, Takano I, Hasegawa M, Takano-Yamamoto T.

Stem Cells Transl Med. 2015 Sep;4(9):993-7. doi: 10.5966/sctm.2014-0292. Epub 2015 Jul 1.


Msx1 controls inductive signaling in mammalian tooth morphogenesis.

Chen Y, Bei M, Woo I, Satokata I, Maas R.

Development. 1996 Oct;122(10):3035-44.


Pathogenic mechanisms of tooth agenesis linked to paired domain mutations in human PAX9.

Wang Y, Groppe JC, Wu J, Ogawa T, Mues G, D'Souza RN, Kapadia H.

Hum Mol Genet. 2009 Aug 1;18(15):2863-74. doi: 10.1093/hmg/ddp221. Epub 2009 May 9.


Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities.

Peters H, Neub├╝ser A, Kratochwil K, Balling R.

Genes Dev. 1998 Sep 1;12(17):2735-47.

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