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Items: 1 to 20 of 112

1.

Widespread and tissue specific age-related DNA methylation changes in mice.

Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, Zhang N, Liang S, Donehower LA, Issa JP.

Genome Res. 2010 Mar;20(3):332-40. doi: 10.1101/gr.096826.109. Epub 2010 Jan 27.

2.

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores.

Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, Onyango P, Cui H, Gabo K, Rongione M, Webster M, Ji H, Potash J, Sabunciyan S, Feinberg AP.

Nat Genet. 2009 Feb;41(2):178-186. doi: 10.1038/ng.298. Epub 2009 Jan 18.

3.

Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.

Chung W, Kwabi-Addo B, Ittmann M, Jelinek J, Shen L, Yu Y, Issa JP.

PLoS One. 2008 Apr 30;3(4):e2079. doi: 10.1371/journal.pone.0002079. Erratum in: PLoS ONE. 2008;3(5). doi: 10.1371/annotation/2548989f-1f13-4ea5-8af8-62420b0a590e.

4.

Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

Yuan J, Luo RZ, Fujii S, Wang L, Hu W, Andreeff M, Pan Y, Kadota M, Oshimura M, Sahin AA, Issa JP, Bast RC Jr, Yu Y.

Cancer Res. 2003 Jul 15;63(14):4174-80.

5.

Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.

Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT.

PLoS Genet. 2009 Aug;5(8):e1000602. doi: 10.1371/journal.pgen.1000602. Epub 2009 Aug 14.

6.

Age-related DNA methylation changes in normal human prostate tissues.

Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP.

Clin Cancer Res. 2007 Jul 1;13(13):3796-802.

7.

Accelerated age-related CpG island methylation in ulcerative colitis.

Issa JP, Ahuja N, Toyota M, Bronner MP, Brentnall TA.

Cancer Res. 2001 May 1;61(9):3573-7.

8.

A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.

Shames DS, Girard L, Gao B, Sato M, Lewis CM, Shivapurkar N, Jiang A, Perou CM, Kim YH, Pollack JR, Fong KM, Lam CL, Wong M, Shyr Y, Nanda R, Olopade OI, Gerald W, Euhus DM, Shay JW, Gazdar AF, Minna JD.

PLoS Med. 2006 Dec;3(12):e486.

9.

DNA methylation differences associated with tumor tissues identified by genome scanning analysis.

Liang G, Salem CE, Yu MC, Nguyen HD, Gonzales FA, Nguyen TT, Nichols PW, Jones PA.

Genomics. 1998 Nov 1;53(3):260-8.

PMID:
9799591
10.

Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells.

Selmin OI, Fang C, Lyon AM, Doetschman TC, Thompson PA, Martinez JD, Smith JW, Lance PM, Romagnolo DF.

J Nutr. 2016 Feb;146(2):236-42. doi: 10.3945/jn.115.216580. Epub 2015 Nov 25.

PMID:
26609171
11.

A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation.

McCabe MT, Lee EK, Vertino PM.

Cancer Res. 2009 Jan 1;69(1):282-91. doi: 10.1158/0008-5472.CAN-08-3274.

12.

Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.

Neumann O, Kesselmeier M, Geffers R, Pellegrino R, Radlwimmer B, Hoffmann K, Ehemann V, Schemmer P, Schirmacher P, Lorenzo Bermejo J, Longerich T.

Hepatology. 2012 Nov;56(5):1817-27. doi: 10.1002/hep.25870. Epub 2012 Oct 14.

PMID:
22689435
13.

CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer.

Ferreira HJ, Heyn H, Moutinho C, Esteller M.

RNA Biol. 2012 Jun;9(6):881-90. doi: 10.4161/rna.19353. Epub 2012 May 23.

14.

Aging, methylation and cancer.

Ahuja N, Issa JP.

Histol Histopathol. 2000 Jul;15(3):835-42. Review.

PMID:
10963127
15.

Frequent aberrant methylation of the promoter region of sterile alpha motif domain 14 in pulmonary adenocarcinoma.

Sun W, Iijima T, Kano J, Kobayashi H, Li D, Morishita Y, Okubo C, Anami Y, Noguchi M.

Cancer Sci. 2008 Nov;99(11):2177-84. doi: 10.1111/j.1349-7006.2008.00965.x. Epub 2008 Sep 22.

16.

DNA methylation biomarker candidates for early detection of colon cancer.

Yi JM, Dhir M, Guzzetta AA, Iacobuzio-Donahue CA, Heo K, Yang KM, Suzuki H, Toyota M, Kim HM, Ahuja N.

Tumour Biol. 2012 Apr;33(2):363-72. doi: 10.1007/s13277-011-0302-2. Epub 2012 Jan 12.

17.

Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.

Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, Shi DR, Wang P, Yang ZH, Zhu JD.

World J Gastroenterol. 2004 Dec 1;10(23):3441-54.

18.
19.

Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal cancer.

Smith JF, Mahmood S, Song F, Morrow A, Smiraglia D, Zhang X, Rajput A, Higgins MJ, Krumm A, Petrelli NJ, Costello JF, Nagase H, Plass C, Held WA.

Epigenetics. 2007 Sep;2(3):161-72. Epub 2007 Jul 27.

PMID:
17965620
20.

High preservation of CpG cytosine methylation patterns at imprinted gene loci in liver and brain of aged mice.

Gravina S, Dollé ME, Wang T, van Steeg H, Hasty P, Hoeijmakers J, Vijg J.

PLoS One. 2013 Sep 9;8(9):e73496. doi: 10.1371/journal.pone.0073496. eCollection 2013.

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