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Items: 1 to 20 of 132

1.

Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer.

Guan JL.

IUBMB Life. 2010 Apr;62(4):268-76. doi: 10.1002/iub.303. Review.

2.
3.

Signal transduction by focal adhesion kinase in cancer.

Zhao J, Guan JL.

Cancer Metastasis Rev. 2009 Jun;28(1-2):35-49. doi: 10.1007/s10555-008-9165-4. Review.

PMID:
19169797
4.

Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.

Wendt MK, Schiemann WP.

Breast Cancer Res. 2009;11(5):R68. doi: 10.1186/bcr2360.

5.

Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.

Fan H, Zhao X, Sun S, Luo M, Guan JL.

J Biol Chem. 2013 Feb 1;288(5):3322-33. doi: 10.1074/jbc.M112.420497. Epub 2012 Dec 19.

6.

Role of focal adhesion kinase in integrin signaling.

Guan JL.

Int J Biochem Cell Biol. 1997 Aug-Sep;29(8-9):1085-96. Review.

PMID:
9416004
7.

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis.

Zhao X, Guan JL.

Adv Drug Deliv Rev. 2011 Jul 18;63(8):610-5. doi: 10.1016/j.addr.2010.11.001. Epub 2010 Nov 29. Review.

8.

Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis.

Luo M, Guan JL.

Cancer Lett. 2010 Mar 28;289(2):127-39. doi: 10.1016/j.canlet.2009.07.005. Epub 2009 Jul 29. Review.

9.

Src and FAK mediate cell-matrix adhesion-dependent activation of Met during transformation of breast epithelial cells.

Hui AY, Meens JA, Schick C, Organ SL, Qiao H, Tremblay EA, Schaeffer E, Uniyal S, Chan BM, Elliott BE.

J Cell Biochem. 2009 Aug 15;107(6):1168-81. doi: 10.1002/jcb.22219.

PMID:
19533669
10.
11.

Integrins in mammary-stem-cell biology and breast-cancer progression--a role in cancer stem cells?

Pontier SM, Muller WJ.

J Cell Sci. 2009 Jan 15;122(Pt 2):207-14. doi: 10.1242/jcs.040394. Review.

12.

Astrocytoma adhesion to extracellular matrix: functional significance of integrin and focal adhesion kinase expression.

Rutka JT, Muller M, Hubbard SL, Forsdike J, Dirks PB, Jung S, Tsugu A, Ivanchuk S, Costello P, Mondal S, Ackerley C, Becker LE.

J Neuropathol Exp Neurol. 1999 Feb;58(2):198-209.

PMID:
10029102
13.

Distinct FAK activities determine progenitor and mammary stem cell characteristics.

Luo M, Zhao X, Chen S, Liu S, Wicha MS, Guan JL.

Cancer Res. 2013 Sep 1;73(17):5591-602. doi: 10.1158/0008-5472.CAN-13-1351. Epub 2013 Jul 5.

15.

Integrin-regulated FAK-Src signaling in normal and cancer cells.

Mitra SK, Schlaepfer DD.

Curr Opin Cell Biol. 2006 Oct;18(5):516-23. Epub 2006 Aug 17. Review.

PMID:
16919435
16.

Inhibition of Focal Adhesion Kinase Signaling by Integrin α6β1 Supports Human Pluripotent Stem Cell Self-Renewal.

Villa-Diaz LG, Kim JK, Laperle A, Palecek SP, Krebsbach PH.

Stem Cells. 2016 Jul;34(7):1753-64. doi: 10.1002/stem.2349. Epub 2016 Mar 27.

17.

An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer.

Tai YL, Chu PY, Lai IR, Wang MY, Tseng HY, Guan JL, Liou JY, Shen TL.

Sci Rep. 2015 Nov 9;5:16408. doi: 10.1038/srep16408.

18.

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells.

Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL.

Cancer Res. 2009 Jan 15;69(2):466-74. doi: 10.1158/0008-5472.CAN-08-3078.

19.

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.

Schlaepfer DD, Hanks SK, Hunter T, van der Geer P.

Nature. 1994 Dec 22-29;372(6508):786-91.

PMID:
7997267
20.

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