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Items: 1 to 20 of 179

1.

Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver.

Bektas M, Allende ML, Lee BG, Chen W, Amar MJ, Remaley AT, Saba JD, Proia RL.

J Biol Chem. 2010 Apr 2;285(14):10880-9. doi: 10.1074/jbc.M109.081489.

2.

Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons.

Hagen-Euteneuer N, Lütjohann D, Park H, Merrill AH Jr, van Echten-Deckert G.

J Biol Chem. 2012 Mar 16;287(12):9128-36. doi: 10.1074/jbc.M111.302380.

3.

Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.

Allende ML, Bektas M, Lee BG, Bonifacino E, Kang J, Tuymetova G, Chen W, Saba JD, Proia RL.

J Biol Chem. 2011 Mar 4;286(9):7348-58. doi: 10.1074/jbc.M110.171819.

4.

Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation.

Wakashima T, Abe K, Kihara A.

J Biol Chem. 2014 Sep 5;289(36):24736-48. doi: 10.1074/jbc.M114.571869.

5.

Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids.

Kihara A.

Biochim Biophys Acta. 2014 May;1841(5):766-72. doi: 10.1016/j.bbalip.2013.08.014. Review.

PMID:
23994042
6.

Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest.

Gorshkova IA, Wang H, Orbelyan GA, Goya J, Natarajan V, Beiser DG, Vanden Hoek TL, Berdyshev EV.

Life Sci. 2013 Sep 17;93(9-11):359-66. doi: 10.1016/j.lfs.2013.07.017.

PMID:
23892195
7.

Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm.

Kihara A, Ikeda M, Kariya Y, Lee EY, Lee YM, Igarashi Y.

J Biol Chem. 2003 Apr 18;278(16):14578-85.

8.

Sphingolipid-to-glycerophospholipid conversion in SPL-null cells implies the existence of an alternative isozyme.

Ikeda M, Kihara A, Kariya Y, Lee YM, Igarashi Y.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):474-9.

PMID:
15737611
9.

Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis.

Allende ML, Sipe LM, Tuymetova G, Wilson-Henjum KL, Chen W, Proia RL.

J Biol Chem. 2013 Jun 21;288(25):18381-91. doi: 10.1074/jbc.M113.478420.

10.

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.

Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA.

J Biol Chem. 2005 Jul 29;280(30):27879-87.

11.

Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice.

Kim DH, Lee YS, Lee YM, Oh S, Yun YP, Yoo HS.

Arch Pharm Res. 2007 Aug;30(8):962-9.

PMID:
17879749
12.

Enhanced Ca2+ storage in sphingosine-1-phosphate lyase-deficient fibroblasts.

Claas RF, ter Braak M, Hegen B, Hardel V, Angioni C, Schmidt H, Jakobs KH, Van Veldhoven PP, zu Heringdorf DM.

Cell Signal. 2010 Mar;22(3):476-83. doi: 10.1016/j.cellsig.2009.11.001.

PMID:
19913094
13.

Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.

Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH Jr, Futerman AH.

J Biol Chem. 2008 Feb 29;283(9):5677-84. doi: 10.1074/jbc.M707386200.

14.

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B.

PLoS One. 2016 Apr 21;11(4):e0153009. doi: 10.1371/journal.pone.0153009.

15.

Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts.

Ihlefeld K, Claas RF, Koch A, Pfeilschifter JM, Meyer Zu Heringdorf D.

Biochem J. 2012 Nov 1;447(3):457-64. doi: 10.1042/BJ20120811.

PMID:
22908849
16.

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability.

Johnson KR, Johnson KY, Becker KP, Bielawski J, Mao C, Obeid LM.

J Biol Chem. 2003 Sep 5;278(36):34541-7.

17.

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.

Hagen N, Hans M, Hartmann D, Swandulla D, van Echten-Deckert G.

Cell Death Differ. 2011 Aug;18(8):1356-65. doi: 10.1038/cdd.2011.7.

18.

A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.

Pewzner-Jung Y, Park H, Laviad EL, Silva LC, Lahiri S, Stiban J, Erez-Roman R, Brügger B, Sachsenheimer T, Wieland F, Prieto M, Merrill AH Jr, Futerman AH.

J Biol Chem. 2010 Apr 2;285(14):10902-10. doi: 10.1074/jbc.M109.077594.

19.

Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.

Kihara A, Mitsutake S, Mizutani Y, Igarashi Y.

Prog Lipid Res. 2007 Mar;46(2):126-44. Review.

PMID:
17449104
20.

Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy.

Nguyen-Tran DH, Hait NC, Sperber H, Qi J, Fischer K, Ieronimakis N, Pantoja M, Hays A, Allegood J, Reyes M, Spiegel S, Ruohola-Baker H.

Dis Model Mech. 2014 Jan;7(1):41-54. doi: 10.1242/dmm.013631.

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