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Items: 1 to 20 of 95

1.

Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila.

Sanokawa-Akakura R, Cao W, Allan K, Patel K, Ganesh A, Heiman G, Burke R, Kemp FW, Bogden JD, Camakaris J, Birge RB, Konsolaki M.

PLoS One. 2010 Jan 13;5(1):e8626. doi: 10.1371/journal.pone.0008626.

2.

A novel role for the immunophilin FKBP52 in copper transport.

Sanokawa-Akakura R, Dai H, Akakura S, Weinstein D, Fajardo JE, Lang SE, Wadsworth S, Siekierka J, Birge RB.

J Biol Chem. 2004 Jul 2;279(27):27845-8. Epub 2004 May 7.

3.

Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.

Lang M, Fan Q, Wang L, Zheng Y, Xiao G, Wang X, Wang W, Zhong Y, Zhou B.

Neurobiol Aging. 2013 Nov;34(11):2604-12. doi: 10.1016/j.neurobiolaging.2013.05.029. Epub 2013 Jul 2.

4.

Role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation.

Hou P, Liu G, Zhao Y, Shi Z, Zheng Q, Bu G, Xu H, Zhang YW.

Neurobiol Aging. 2015 Mar;36(3):1310-5. doi: 10.1016/j.neurobiolaging.2014.12.005. Epub 2014 Dec 11.

PMID:
25557959
5.

A novel role for the immunophilin FKBP52 in motor coordination.

Young MJ, Geiszler PC, Pardon MC.

Behav Brain Res. 2016 Oct 15;313:97-110. doi: 10.1016/j.bbr.2016.07.015. Epub 2016 Jul 11.

PMID:
27418439
6.

FKBP immunophilins and Alzheimer's disease: a chaperoned affair.

Cao W, Konsolaki M.

J Biosci. 2011 Aug;36(3):493-8. Review.

7.

Three-step purification of a fragment of the large immunophilin FKBP52.

Pirkl F.

J Chromatogr B Biomed Sci Appl. 2000 Jan 14;737(1-2):71-6.

PMID:
10681043
8.

Association of immunophilins with mammalian TRPC channels.

Sinkins WG, Goel M, Estacion M, Schilling WP.

J Biol Chem. 2004 Aug 13;279(33):34521-9. Epub 2004 Jun 15.

10.

FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.

Wochnik GM, Rüegg J, Abel GA, Schmidt U, Holsboer F, Rein T.

J Biol Chem. 2005 Feb 11;280(6):4609-16. Epub 2004 Dec 9.

11.

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.

Bellingham SA, Ciccotosto GD, Needham BE, Fodero LR, White AR, Masters CL, Cappai R, Camakaris J.

J Neurochem. 2004 Oct;91(2):423-8.

12.

Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease.

Kar S, Slowikowski SP, Westaway D, Mount HT.

J Psychiatry Neurosci. 2004 Nov;29(6):427-41. Review.

13.

Proteomic analysis identifies immunophilin FK506 binding protein 4 (FKBP52) as a downstream target of Hoxa10 in the periimplantation mouse uterus.

Daikoku T, Tranguch S, Friedman DB, Das SK, Smith DF, Dey SK.

Mol Endocrinol. 2005 Mar;19(3):683-97. Epub 2004 Nov 4.

PMID:
15528267
14.

Physiological role for the cochaperone FKBP52 in androgen receptor signaling.

Cheung-Flynn J, Prapapanich V, Cox MB, Riggs DL, Suarez-Quian C, Smith DF.

Mol Endocrinol. 2005 Jun;19(6):1654-66. Epub 2005 Apr 14.

PMID:
15831525
15.

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.

Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R.

J Biol Chem. 2003 May 9;278(19):17401-7. Epub 2003 Feb 28.

16.

Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils.

Poduslo JF, Howell KG, Olson NC, Ramirez-Alvarado M, Kandimalla KK.

Biochemistry. 2012 May 15;51(19):3993-4003. doi: 10.1021/bi300275g. Epub 2012 May 7.

PMID:
22545812
17.

Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments.

Page RM, Münch A, Horn T, Kuhn PH, Colombo A, Reiner O, Boutros M, Steiner H, Lichtenthaler SF, Haass C.

J Neurosci. 2012 Dec 12;32(50):18204-14. doi: 10.1523/JNEUROSCI.2681-12.2012.

18.

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.

Giustiniani J, Chambraud B, Sardin E, Dounane O, Guillemeau K, Nakatani H, Paquet D, Kamah A, Landrieu I, Lippens G, Baulieu EE, Tawk M.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4584-9. doi: 10.1073/pnas.1402645111. Epub 2014 Mar 12.

19.

The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures.

White AR, Multhaup G, Maher F, Bellingham S, Camakaris J, Zheng H, Bush AI, Beyreuther K, Masters CL, Cappai R.

J Neurosci. 1999 Nov 1;19(21):9170-9.

20.

Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge.

Bracher A, Kozany C, Hähle A, Wild P, Zacharias M, Hausch F.

J Mol Biol. 2013 Nov 15;425(22):4134-44. doi: 10.1016/j.jmb.2013.07.041. Epub 2013 Aug 8.

PMID:
23933011

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