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Items: 1 to 20 of 125

1.

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes.

Tsuchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, Marcu KB, Komiya S, Ijiri K, Goldring MB.

J Biol Chem. 2010 Mar 12;285(11):8395-407. doi: 10.1074/jbc.M109.038638. Epub 2010 Jan 4.

2.

Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.

Shimada H, Sakakima H, Tsuchimochi K, Matsuda F, Komiya S, Goldring MB, Ijiri K.

Pathol Res Pract. 2011 Apr 15;207(4):225-31. doi: 10.1016/j.prp.2011.01.007. Epub 2011 Feb 24.

3.

CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes.

Ushijima T, Okazaki K, Tsushima H, Iwamoto Y.

J Biol Chem. 2014 Jan 31;289(5):2852-63. doi: 10.1074/jbc.M113.492843. Epub 2013 Dec 16.

4.

Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins.

Okuma T, Hirata M, Yano F, Mori D, Kawaguchi H, Chung UI, Tanaka S, Saito T.

Biomed Res. 2015;36(1):21-9. doi: 10.2220/biomedres.36.21.

5.

CCAAT/enhancer binding protein β (C/EBPβ) regulates the transcription of growth arrest and DNA damage-inducible protein 45 β (GADD45β) in articular chondrocytes.

Shimada H, Otero M, Tsuchimochi K, Yamasaki S, Sakakima H, Matsuda F, Sakasegawa M, Setoguchi T, Xu L, Goldring MB, Tanimoto A, Komiya S, Ijiri K.

Pathol Res Pract. 2016 Apr;212(4):302-9. doi: 10.1016/j.prp.2016.01.009. Epub 2016 Jan 27.

6.

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.

Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB.

J Biol Chem. 2005 Nov 18;280(46):38544-55. Epub 2005 Sep 2.

7.

SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.

Leung VY, Gao B, Leung KK, Melhado IG, Wynn SL, Au TY, Dung NW, Lau JY, Mak AC, Chan D, Cheah KS.

PLoS Genet. 2011 Nov;7(11):e1002356. doi: 10.1371/journal.pgen.1002356. Epub 2011 Nov 3.

8.

IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.

Cortez DM, Feldman MD, Mummidi S, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3356-65. Epub 2007 Oct 5.

PMID:
17921324
9.

Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.

Li Y, Batra S, Sassano A, Majchrzak B, Levy DE, Gaestel M, Fish EN, Davis RJ, Platanias LC.

J Biol Chem. 2005 Mar 18;280(11):10001-10. Epub 2005 Jan 11. Erratum in: J Biol Chem. 2006 Apr 14;281(15):10651.

10.

A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo.

Gebhard S, Pöschl E, Riemer S, Bauer E, Hattori T, Eberspaecher H, Zhang Z, Lefebvre V, de Crombrugghe B, von der Mark K.

Matrix Biol. 2004 Aug;23(5):309-22.

PMID:
15464363
11.

The p38-MSK1 signaling cascade influences cytokine production through CREB and C/EBP factors in human neutrophils.

Mayer TZ, Simard FA, Cloutier A, Vardhan H, Dubois CM, McDonald PP.

J Immunol. 2013 Oct 15;191(8):4299-307. doi: 10.4049/jimmunol.1301117. Epub 2013 Sep 13.

12.

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.

Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H.

Hum Mol Genet. 2012 Mar 1;21(5):1111-23. doi: 10.1093/hmg/ddr540. Epub 2011 Nov 17.

PMID:
22095691
13.

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

Chi H, Lu B, Takekawa M, Davis RJ, Flavell RA.

EMBO J. 2004 Apr 7;23(7):1576-86. Epub 2004 Mar 25.

15.

Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta.

Kagan BL, Henke RT, Cabal-Manzano R, Stoica GE, Nguyen Q, Wellstein A, Riegel AT.

Cancer Res. 2003 Apr 1;63(7):1696-705.

16.

PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.

Adhikary G, Chew YC, Reece EA, Eckert RL.

J Invest Dermatol. 2010 Aug;130(8):2017-30. doi: 10.1038/jid.2010.108. Epub 2010 May 6.

17.

CCAAT/enhancer binding protein β regulates expression of Indian hedgehog during chondrocytes differentiation.

Ushijima T, Okazaki K, Tsushima H, Ishihara K, Doi T, Iwamoto Y.

PLoS One. 2014 Aug 8;9(8):e104547. doi: 10.1371/journal.pone.0104547. eCollection 2014.

18.
20.

Extracellular regulated kinase 1/2 signaling is a critical regulator of interleukin-1β-mediated astrocyte tissue inhibitor of metalloproteinase-1 expression.

Fields J, Cisneros IE, Borgmann K, Ghorpade A.

PLoS One. 2013;8(2):e56891. doi: 10.1371/journal.pone.0056891. Epub 2013 Feb 14.

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