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Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription.

Tran K, Mahr JA, Spector DH.

J Virol. 2010 Mar;84(6):3079-93. doi: 10.1128/JVI.02236-09. Epub 2009 Dec 30.


The 19S proteasome activator promotes human cytomegalovirus immediate early gene expression through proteolytic and nonproteolytic mechanisms.

Winkler LL, Kalejta RF.

J Virol. 2014 Oct;88(20):11782-90. doi: 10.1128/JVI.01720-14. Epub 2014 Jul 30.


Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.

Kaspari M, Tavalai N, Stamminger T, Zimmermann A, Schilf R, Bogner E.

FEBS Lett. 2008 Mar 5;582(5):666-72. doi: 10.1016/j.febslet.2008.01.040. Epub 2008 Jan 31.


Coordination of late gene transcription of human cytomegalovirus with viral DNA synthesis: recombinant viruses as potential therapeutic vaccine candidates.

Isomura H, Stinski MF.

Expert Opin Ther Targets. 2013 Feb;17(2):157-66. doi: 10.1517/14728222.2013.740460. Epub 2012 Dec 12. Review.


Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.

Qian Z, Leung-Pineda V, Xuan B, Piwnica-Worms H, Yu D.

PLoS Pathog. 2010 Mar 19;6(3):e1000814. doi: 10.1371/journal.ppat.1000814.


The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.

Gariano GR, Dell'Oste V, Bronzini M, Gatti D, Luganini A, De Andrea M, Gribaudo G, Gariglio M, Landolfo S.

PLoS Pathog. 2012 Jan;8(1):e1002498. doi: 10.1371/journal.ppat.1002498. Epub 2012 Jan 26.


The human cytomegalovirus gene products essential for late viral gene expression assemble into prereplication complexes before viral DNA replication.

Isomura H, Stinski MF, Murata T, Yamashita Y, Kanda T, Toyokuni S, Tsurumi T.

J Virol. 2011 Jul;85(13):6629-44. doi: 10.1128/JVI.00384-11. Epub 2011 Apr 20.


Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription.

Perng YC, Campbell JA, Lenschow DJ, Yu D.

PLoS Pathog. 2014 Aug 28;10(8):e1004350. doi: 10.1371/journal.ppat.1004350. eCollection 2014 Aug.


Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.

Tenney DJ, Yamanaka G, Voss SM, Cianci CW, Tuomari AV, Sheaffer AK, Alam M, Colonno RJ.

Antimicrob Agents Chemother. 1997 Dec;41(12):2680-5.


Human cytomegalovirus microRNA miR-US25-1-5p inhibits viral replication by targeting multiple cellular genes during infection.

Jiang S, Qi Y, He R, Huang Y, Liu Z, Ma Y, Guo X, Shao Y, Sun Z, Ruan Q.

Gene. 2015 Oct 1;570(1):108-14. doi: 10.1016/j.gene.2015.06.009. Epub 2015 Jun 6.


Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines.

Sadanari H, Tanaka J, Li Z, Yamada R, Matsubara K, Murayama T.

Virus Res. 2009 Jun;142(1-2):68-77. doi: 10.1016/j.virusres.2009.01.010. Epub 2009 Feb 6.


Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment.

Xie M, Xuan B, Shan J, Pan D, Sun Y, Shan Z, Zhang J, Yu D, Li B, Qian Z.

J Virol. 2015 Mar;89(6):3049-61. doi: 10.1128/JVI.03416-14. Epub 2014 Dec 31.


Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication.

Zhu H, Cong JP, Yu D, Bresnahan WA, Shenk TE.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3932-7. Epub 2002 Feb 26.


PD0084430: a non-nucleoside inhibitor of human cytomegalovirus replication in vitro.

Meyer AL, Bruening EE, Dunkle WE, Booth RJ, Steinbaugh BA, Vara Prasad JV.

Antiviral Res. 2001 Dec;52(3):289-300.


Mutual Interplay between the Human Cytomegalovirus Terminase Subunits pUL51, pUL56, and pUL89 Promotes Terminase Complex Formation.

Neuber S, Wagner K, Goldner T, Lischka P, Steinbrueck L, Messerle M, Borst EM.

J Virol. 2017 May 26;91(12). pii: e02384-16. doi: 10.1128/JVI.02384-16. Print 2017 Jun 15.


Cyclophilin A is required for efficient human cytomegalovirus DNA replication and reactivation.

Keyes LR, Bego MG, Soland M, St Jeor S.

J Gen Virol. 2012 Apr;93(Pt 4):722-32. doi: 10.1099/vir.0.037309-0. Epub 2012 Jan 13.

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