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Items: 1 to 20 of 81

1.

Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines.

Cipres A, O'Malley DP, Li K, Finlay D, Baran PS, Vuori K.

ACS Chem Biol. 2010 Feb 19;5(2):195-202. doi: 10.1021/cb900240k.

2.

Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol.

Rodríguez AD, Lear MJ, La Clair JJ.

J Am Chem Soc. 2008 Jun 11;130(23):7256-8. doi: 10.1021/ja7114019. Epub 2008 May 14.

PMID:
18479102
3.

A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana.

Bernan VS, Roll DM, Ireland CM, Greenstein M, Maiese WM, Steinberg DA.

J Antimicrob Chemother. 1993 Oct;32(4):539-50.

PMID:
8288495
4.

From anti-fouling to biofilm inhibition: new cytotoxic secondary metabolites from two Indonesian Agelas sponges.

Hertiani T, Edrada-Ebel R, Ortlepp S, van Soest RW, de Voogd NJ, Wray V, Hentschel U, Kozytska S, Müller WE, Proksch P.

Bioorg Med Chem. 2010 Feb;18(3):1297-311. doi: 10.1016/j.bmc.2009.12.028. Epub 2010 Jan 12.

PMID:
20061160
5.

Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence.

Ma Z, Wang X, Wang X, Rodriguez RA, Moore CE, Gao S, Tan X, Ma Y, Rheingold AL, Baran PS, Chen C.

Science. 2014 Oct 10;346(6206):219-24. doi: 10.1126/science.1255677.

6.

Bromopyrrole alkaloids as lead compounds against protozoan parasites.

Scala F, Fattorusso E, Menna M, Taglialatela-Scafati O, Tierney M, Kaiser M, Tasdemir D.

Mar Drugs. 2010 Jul 14;8(7):2162-74. doi: 10.3390/md8072162.

7.

Anti-muscarinic activity of a family of C11N5 compounds isolated from Agelas sponges.

Rosa R, Silva W, Escalona de Motta G, Rodríguez AD, Morales JJ, Ortiz M.

Experientia. 1992 Sep 15;48(9):885-7.

PMID:
1397186
8.

Agelastatin E, agelastatin F, and benzosceptrin C from the marine sponge Agelas dendromorpha.

Tilvi S, Moriou C, Martin MT, Gallard JF, Sorres J, Patel K, Petek S, Debitus C, Ermolenko L, Al-Mourabit A.

J Nat Prod. 2010 Apr 23;73(4):720-3. doi: 10.1021/np900539j.

PMID:
20166736
9.

Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration.

Sallam AA, Ramasahayam S, Meyer SA, El Sayed KA.

Bioorg Med Chem. 2010 Nov 1;18(21):7446-57. doi: 10.1016/j.bmc.2010.08.057. Epub 2010 Sep 29.

PMID:
20884214
10.

New bromopyrrole alkaloids from the Indopacific sponge Agelas nakamurai.

Eder C, Proksch P, Wray V, van Soest RW, Ferdinandus E, Pattisina LA, Sudarsono S.

J Nat Prod. 1999 Sep;62(9):1295-7.

PMID:
10514317
11.

Effects of Agelas oroides and Petrosia ficiformis crude extracts on human neuroblastoma cell survival.

Ferretti C, Marengo B, De Ciucis C, Nitti M, Pronzato MA, Marinari UM, Pronzato R, Manconi R, Domenicotti C.

Int J Oncol. 2007 Jan;30(1):161-9.

PMID:
17143525
12.
13.

Brominated pyrrole alkaloids from marine Agelas sponges reduce depolarization-induced cellular calcium elevation.

Bickmeyer U, Drechsler C, Köck M, Assmann M.

Toxicon. 2004 Jul;44(1):45-51.

PMID:
15225561
14.

The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism.

Franzen CA, Amargo E, Todorović V, Desai BV, Huda S, Mirzoeva S, Chiu K, Grzybowski BA, Chew TL, Green KJ, Pelling JC.

Cancer Prev Res (Phila). 2009 Sep;2(9):830-41. doi: 10.1158/1940-6207.CAPR-09-0066. Epub 2009 Sep 8.

15.

Screening of a PKC zeta-specific kinase inhibitor PKCzI257.3 which inhibits EGF-induced breast cancer cell chemotaxis.

Wu J, Zhang B, Wu M, Li H, Niu R, Ying G, Zhang N.

Invest New Drugs. 2010 Jun;28(3):268-75. doi: 10.1007/s10637-009-9242-8. Epub 2009 Mar 27.

PMID:
19326049
16.

Synthesis and in vitro antiproliferative activity of amido and amino analogues of the marine alkaloid isogranulatimide.

Lavrard H, Salvetti B, Mathieu V, Rodriguez F, Kiss R, Delfourne E.

ChemMedChem. 2015 Apr;10(4):607-9. doi: 10.1002/cmdc.201500025. Epub 2015 Mar 3.

PMID:
25735892
17.

De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis.

Stout EP, Morinaka BI, Wang YG, Romo D, Molinski TF.

J Nat Prod. 2012 Apr 27;75(4):527-30. doi: 10.1021/np300051k. Epub 2012 Mar 28.

18.

Synthesis and anticancer activity of focused compound libraries from the natural product lead, oroidin.

Dyson L, Wright AD, Young KA, Sakoff JA, McCluskey A.

Bioorg Med Chem. 2014 Mar 1;22(5):1690-9. doi: 10.1016/j.bmc.2014.01.021. Epub 2014 Jan 24.

PMID:
24508308
19.
20.

Synthesis and SAR studies of marine natural products ma'edamines A, B and their analogues.

Saha S, Reddy ChV, Xu S, Sankar S, Neamati N, Patro B.

Bioorg Med Chem Lett. 2013 Sep 15;23(18):5135-9. doi: 10.1016/j.bmcl.2013.07.017. Epub 2013 Jul 19.

PMID:
23927972

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