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Items: 1 to 20 of 126

1.

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing.

Gamble MJ, Frizzell KM, Yang C, Krishnakumar R, Kraus WL.

Genes Dev. 2010 Jan 1;24(1):21-32. doi: 10.1101/gad.1876110. Epub 2009 Dec 15.

2.

The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.

Hussey KM, Chen H, Yang C, Park E, Hah N, Erdjument-Bromage H, Tempst P, Gamble MJ, Kraus WL.

Mol Cell Biol. 2014 Jul;34(13):2437-49. doi: 10.1128/MCB.01315-13. Epub 2014 Apr 21.

3.

MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis.

Podrini C, Koffas A, Chokshi S, Vinciguerra M, Lelliott CJ, White JK, Adissu HA, Williams R, Greco A.

FASEB J. 2015 May;29(5):1676-87. doi: 10.1096/fj.14-262717. Epub 2014 Dec 19.

4.

Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domains.

Ioudinkova ES, Barat A, Pichugin A, Markova E, Sklyar I, Pirozhkova I, Robin C, Lipinski M, Ogryzko V, Vassetzky YS, Razin SV.

PLoS One. 2012;7(10):e47157. doi: 10.1371/journal.pone.0047157. Epub 2012 Oct 30.

5.

MacroH2A1 knockdown effects on the Peg3 imprinted domain.

Choo JH, Kim JD, Kim J.

BMC Genomics. 2007 Dec 31;8:479. doi: 10.1186/1471-2164-8-479.

6.

Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).

Barzily-Rokni M, Friedman N, Ron-Bigger S, Isaac S, Michlin D, Eden A.

Nucleic Acids Res. 2011 Mar;39(4):1326-35. doi: 10.1093/nar/gkq994. Epub 2010 Oct 28.

7.
8.

The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome.

Nusinow DA, Sharp JA, Morris A, Salas S, Plath K, Panning B.

J Mol Biol. 2007 Aug 3;371(1):11-8. Epub 2007 May 26.

9.

Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.

Changolkar LN, Singh G, Cui K, Berletch JB, Zhao K, Disteche CM, Pehrson JR.

Mol Cell Biol. 2010 Dec;30(23):5473-83. doi: 10.1128/MCB.00518-10. Epub 2010 Oct 11.

10.

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation.

Chen H, Ruiz PD, Novikov L, Casill AD, Park JW, Gamble MJ.

Nat Struct Mol Biol. 2014 Nov;21(11):981-9. doi: 10.1038/nsmb.2903. Epub 2014 Oct 12.

11.

Chromatin signature of embryonic pluripotency is established during genome activation.

Vastenhouw NL, Zhang Y, Woods IG, Imam F, Regev A, Liu XS, Rinn J, Schier AF.

Nature. 2010 Apr 8;464(7290):922-6. doi: 10.1038/nature08866. Epub 2010 Mar 24.

12.

Long range epigenetic silencing is a trans-species mechanism that results in cancer specific deregulation by overriding the chromatin domains of normal cells.

Forn M, Muñoz M, Tauriello DV, Merlos-Suárez A, Rodilla V, Bigas A, Batlle E, Jordà M, Peinado MA.

Mol Oncol. 2013 Dec;7(6):1129-41. doi: 10.1016/j.molonc.2013.08.008. Epub 2013 Aug 30.

13.

Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.

Chadwick BP, Willard HF.

Hum Mol Genet. 2001 May 1;10(10):1101-13.

PMID:
11331621
14.

Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells.

Takayama K, Tsutsumi S, Katayama S, Okayama T, Horie-Inoue K, Ikeda K, Urano T, Kawazu C, Hasegawa A, Ikeo K, Gojyobori T, Ouchi Y, Hayashizaki Y, Aburatani H, Inoue S.

Oncogene. 2011 Feb 3;30(5):619-30. doi: 10.1038/onc.2010.436. Epub 2010 Oct 4.

PMID:
20890304
15.

Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos.

Lindeman LC, Winata CL, Aanes H, Mathavan S, Alestrom P, Collas P.

Int J Dev Biol. 2010;54(5):803-13. doi: 10.1387/ijdb.103081ll.

16.

Allele-specific deposition of macroH2A1 in imprinting control regions.

Choo JH, Kim JD, Chung JH, Stubbs L, Kim J.

Hum Mol Genet. 2006 Mar 1;15(5):717-24. Epub 2006 Jan 18.

PMID:
16421169
17.

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression.

Borghesan M, Fusilli C, Rappa F, Panebianco C, Rizzo G, Oben JA, Mazzoccoli G, Faulkes C, Pata I, Agodi A, Rezaee F, Minogue S, Warren A, Peterson A, Sedivy JM, Douet J, Buschbeck M, Cappello F, Mazza T, Pazienza V, Vinciguerra M.

Cancer Res. 2016 Feb 1;76(3):594-606. doi: 10.1158/0008-5472.CAN-15-1336. Epub 2016 Jan 15.

18.

E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9.

Oberley MJ, Inman DR, Farnham PJ.

J Biol Chem. 2003 Oct 24;278(43):42466-76. Epub 2003 Aug 8.

19.

Genome-wide bovine H3K27me3 modifications and the regulatory effects on genes expressions in peripheral blood lymphocytes.

He Y, Yu Y, Zhang Y, Song J, Mitra A, Zhang Y, Wang Y, Sun D, Zhang S.

PLoS One. 2012;7(6):e39094. doi: 10.1371/journal.pone.0039094. Epub 2012 Jun 28.

20.

Differentially expressed genes are marked by histone 3 lysine 9 trimethylation in human cancer cells.

Wiencke JK, Zheng S, Morrison Z, Yeh RF.

Oncogene. 2008 Apr 10;27(17):2412-21. Epub 2007 Oct 29.

PMID:
17968314

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