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Items: 1 to 20 of 79

1.

Radiotherapy in conjunction with 7-hydroxystaurosporine: a multimodal approach with tumor pO2 as a potential marker of therapeutic response.

Khan N, Mupparaju SP, Hou H, Lariviere JP, Demidenko E, Swartz HM, Eastman A.

Radiat Res. 2009 Nov;172(5):592-7. doi: 10.1667/RR1781.1.

2.
4.

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.

J Natl Cancer Inst. 1996 Jul 17;88(14):956-65.

PMID:
8667426
5.

Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas.

Mupparaju S, Hou H, Lariviere JP, Swartz H, Jounaidi Y, Khan N.

Oncol Rep. 2011 Jul;26(1):281-6. doi: 10.3892/or.2011.1268. Epub 2011 Apr 15.

6.

Assessment of the changes in 9L and C6 glioma pO2 by EPR oximetry as a prognostic indicator of differential response to radiotherapy.

Hou H, Mupparaju SP, Lariviere JP, Hodge S, Gui J, Swartz HM, Khan N.

Radiat Res. 2013 Mar;179(3):343-51. doi: 10.1667/RR2811.1. Epub 2013 Feb 7.

7.

7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism.

Cartee L, Sankala H, Davis C, Smith R, Maggio S, Lin PS, Dent P, Grant S.

Int J Oncol. 2002 Aug;21(2):351-9.

PMID:
12118331
9.

Synergistic combination of hyperoxygenation and radiotherapy by repeated assessments of tumor pO2 with EPR oximetry.

Hou H, Dong R, Lariviere JP, Mupparaju SP, Swartz HM, Khan N.

J Radiat Res. 2011;52(5):568-74. Epub 2011 Jul 29.

11.

Enhancement of radiation cytotoxicity by UCN-01 in non-small cell lung carcinoma cells.

Mack PC, Jones AA, Gustafsson MH, Gandara DR, Gumerlock PH, Goldberg Z.

Radiat Res. 2004 Dec;162(6):623-34.

PMID:
15548112
12.
13.

Changes of oxygen tension in experimental tumors after a single dose of X-ray irradiation.

Goda F, O'Hara JA, Rhodes ES, Liu KJ, Dunn JF, Bacic G, Swartz HM.

Cancer Res. 1995 Jun 1;55(11):2249-52.

14.

[Abrogation effect of UCN-01 on radiation-induced G2 phase arrest of tumor cells and its mechanism].

Hui ZG, Li YX, Yang WZ, Yu ZH.

Ai Zheng. 2005 Jan;24(1):1-6. Chinese.

PMID:
15642191
15.

UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines.

Wu G, Lin N, Xu L, Liu B, Feitelson MA.

BMC Cancer. 2013 Mar 28;13:167. doi: 10.1186/1471-2407-13-167. Erratum in: BMC Cancer. 2014;14:216. Feitelson, Mark A [added].

16.

The pO2 in a murine tumor after irradiation: an in vivo electron paramagnetic resonance oximetry study.

O'Hara JA, Goda F, Liu KJ, Bacic G, Hoopes PJ, Swartz HM.

Radiat Res. 1995 Nov;144(2):222-9.

PMID:
7480649
17.

Combined antitumor activity of 7-hydroxystaurosporine (UCN-01) and tamoxifen against human breast carcinoma in vitro and in vivo.

Koh J, Kubota T, Koyama T, Migita T, Hashimoto M, Hosoda Y, Kitajima M.

Breast Cancer. 2003;10(3):260-7.

PMID:
12955040
19.

UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.

Abe S, Kubota T, Otani Y, Furukawa T, Watanabe M, Kumai K, Akiyama T, Akinaga S, Kitajima M.

Jpn J Cancer Res. 2001 May;92(5):537-45.

PMID:
11376563
20.

Effect of a topical vasodilator on tumor hypoxia and tumor oxygen guided radiotherapy using EPR oximetry.

Hou H, Abramovic Z, Lariviere JP, Sentjurc M, Swartz H, Khan N.

Radiat Res. 2010 May;173(5):651-8. doi: 10.1667/RR1947.1.

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