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Items: 1 to 20 of 245

1.

Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis.

Sisson TH, Mendez M, Choi K, Subbotina N, Courey A, Cunningham A, Dave A, Engelhardt JF, Liu X, White ES, Thannickal VJ, Moore BB, Christensen PJ, Simon RH.

Am J Respir Crit Care Med. 2010 Feb 1;181(3):254-63. doi: 10.1164/rccm.200810-1615OC.

2.

Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF.

Pan LH, Yamauchi K, Uzuki M, Nakanishi T, Takigawa M, Inoue H, Sawai T.

Eur Respir J. 2001 Jun;17(6):1220-7.

3.

The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells.

Yamada M, Kubo H, Ota C, Takahashi T, Tando Y, Suzuki T, Fujino N, Makiguchi T, Takagi K, Suzuki T, Ichinose M.

Respir Res. 2013 Sep 24;14:95. doi: 10.1186/1465-9921-14-95.

4.

Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model.

Birkelbach B, Lutz D, Ruppert C, Henneke I, Lopez-Rodriguez E, Günther A, Ochs M, Mahavadi P, Knudsen L.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L63-75. doi: 10.1152/ajplung.00279.2014.

5.

WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis.

Königshoff M, Kramer M, Balsara N, Wilhelm J, Amarie OV, Jahn A, Rose F, Fink L, Seeger W, Schaefer L, Günther A, Eickelberg O.

J Clin Invest. 2009 Apr;119(4):772-87. doi: 10.1172/JCI33950.

6.

Implicating exudate macrophages and Ly-6C(high) monocytes in CCR2-dependent lung fibrosis following gene-targeted alveolar injury.

Osterholzer JJ, Olszewski MA, Murdock BJ, Chen GH, Erb-Downward JR, Subbotina N, Browning K, Lin Y, Morey RE, Dayrit JK, Horowitz JC, Simon RH, Sisson TH.

J Immunol. 2013 Apr 1;190(7):3447-57. doi: 10.4049/jimmunol.1200604.

7.

Prominin-1/CD133+ lung epithelial progenitors protect from bleomycin-induced pulmonary fibrosis.

Germano D, Blyszczuk P, Valaperti A, Kania G, Dirnhofer S, Landmesser U, Lüscher TF, Hunziker L, Zulewski H, Eriksson U.

Am J Respir Crit Care Med. 2009 May 15;179(10):939-49. doi: 10.1164/rccm.200809-1390OC.

PMID:
19234103
8.

Profibrotic potential of prominin-1+ epithelial progenitor cells in pulmonary fibrosis.

Blyszczuk P, Germano D, Stein S, Moch H, Matter CM, Beck-Schimmer B, Lüscher TF, Eriksson U, Kania G.

Respir Res. 2011 Sep 26;12:126. doi: 10.1186/1465-9921-12-126.

9.

Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro.

Ohbayashi M, Suzuki M, Yashiro Y, Fukuwaka S, Yasuda M, Kohyama N, Kobayashi Y, Yamamoto T.

J Toxicol Sci. 2010 Oct;35(5):653-61.

10.

Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis.

Gazdhar A, Fachinger P, van Leer C, Pierog J, Gugger M, Friis R, Schmid RA, Geiser T.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L529-36.

11.

Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1.

Bhandary YP, Shetty SK, Marudamuthu AS, Ji HL, Neuenschwander PF, Boggaram V, Morris GF, Fu J, Idell S, Shetty S.

Am J Pathol. 2013 Jul;183(1):131-43. doi: 10.1016/j.ajpath.2013.03.022.

12.

Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system.

Bhandary YP, Shetty SK, Marudamuthu AS, Gyetko MR, Idell S, Gharaee-Kermani M, Shetty RS, Starcher BC, Shetty S.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 1;302(5):L463-73. doi: 10.1152/ajplung.00099.2011.

13.

PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.

Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH.

J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992.

14.

Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis.

Xu YD, Hua J, Mui A, O'Connor R, Grotendorst G, Khalil N.

Am J Physiol Lung Cell Mol Physiol. 2003 Sep;285(3):L527-39.

15.

The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.

Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX.

Am J Respir Crit Care Med. 2012 Nov 15;186(10):1014-24. doi: 10.1164/rccm.201207-1206OC.

16.

Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

Hoyles RK, Khan K, Shiwen X, Howat SL, Lindahl GE, Leoni P, du Bois RM, Wells AU, Black CM, Abraham DJ, Denton CP.

Arthritis Rheum. 2008 Apr;58(4):1175-88. doi: 10.1002/art.23379. Erratum in: Arthritis Rheum. 2015 Oct;67(10):2741.

17.

Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia.

Parra ER, Pincelli MS, Teodoro WR, Velosa AP, Martins V, Rangel MP, Barbas-Filho JV, Capelozzi VL.

Braz J Med Biol Res. 2014 Jul;47(7):567-75.

18.

Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis.

Ohta H, Chiba S, Ebina M, Furuse M, Nukiwa T.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15;302(2):L193-205. doi: 10.1152/ajplung.00349.2010.

19.

Intratracheal transplantation of alveolar type II cells reverses bleomycin-induced lung fibrosis.

Serrano-Mollar A, Nacher M, Gay-Jordi G, Closa D, Xaubet A, Bulbena O.

Am J Respir Crit Care Med. 2007 Dec 15;176(12):1261-8.

PMID:
17641155
20.

Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor.

Yang J, Velikoff M, Canalis E, Horowitz JC, Kim KK.

Am J Physiol Lung Cell Mol Physiol. 2014 Apr 15;306(8):L786-96. doi: 10.1152/ajplung.00243.2013.

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