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Items: 1 to 20 of 77

1.

TCR signal transduction: opening the black box.

Weiss A.

J Immunol. 2009 Oct 15;183(8):4821-7. doi: 10.4049/jimmunol.0990083. No abstract available.

2.

Initiation of T cell signaling by CD45 segregation at 'close contacts'.

Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJ, Klenerman D, Aricescu AR, Davis SJ.

Nat Immunol. 2016 May;17(5):574-82. doi: 10.1038/ni.3392. Epub 2016 Mar 21.

3.

Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.

Choudhuri K, Parker M, Milicic A, Cole DK, Shaw MK, Sewell AK, Stewart-Jones G, Dong T, Gould KG, van der Merwe PA.

J Biol Chem. 2009 Sep 18;284(38):26096-105. doi: 10.1074/jbc.M109.039966. Epub 2009 Jul 23.

5.

The structure, regulation, and function of ZAP-70.

Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, Kuriyan J, Weiss A.

Immunol Rev. 2009 Mar;228(1):41-57. doi: 10.1111/j.1600-065X.2008.00753.x. Review.

PMID:
19290920
6.

Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4.

Kim KD, Choi JM, Chae WJ, Lee SK.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):355-60. doi: 10.1016/j.bbrc.2009.02.046. Epub 2009 Feb 20.

PMID:
19230824
7.
8.

Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70.

Stone JD, Conroy LA, Byth KF, Hederer RA, Howlett S, Takemoto Y, Holmes N, Alexander DR.

J Immunol. 1997 Jun 15;158(12):5773-82.

PMID:
9190928
9.

Glycosylation changes in hFUT1 transgenic mice increase TCR signaling and apoptosis resulting in thymocyte maturation arrest.

Moore GT, Brown SJ, Winterhalter AC, Lust M, Salvaris EJ, Selan C, Nandurkar HH, Desmond PV, Cowan PJ, d'Apice AJ.

Mol Immunol. 2008 Apr;45(8):2401-10. Epub 2007 Dec 26.

PMID:
18155296
10.

ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.

Schieven GL, Mittler RS, Nadler SG, Kirihara JM, Bolen JB, Kanner SB, Ledbetter JA.

J Biol Chem. 1994 Aug 12;269(32):20718-26.

11.

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.

Di Bartolo V, Mège D, Germain V, Pelosi M, Dufour E, Michel F, Magistrelli G, Isacchi A, Acuto O.

J Biol Chem. 1999 Mar 5;274(10):6285-94.

12.

Turning the tide of lymphocyte costimulation.

Zhu Y, Chen L.

J Immunol. 2009 Mar 1;182(5):2557-8. doi: 10.4049/jimmunol.0990006. No abstract available.

13.

ROZA-XL, an improved FRET based biosensor with an increased dynamic range for visualizing zeta associated protein 70 kD (ZAP-70) tyrosine kinase activity in live T cells.

Cadra S, Gucciardi A, Valignat MP, Theodoly O, Vacaflores A, Houtman JC, Lellouch AC.

Biochem Biophys Res Commun. 2015 Apr 10;459(3):405-10. doi: 10.1016/j.bbrc.2015.02.117. Epub 2015 Feb 28.

PMID:
25735979
14.

Interaction between CD45-AP and protein-tyrosine kinases involved in T cell receptor signaling.

Motoya S, Kitamura K, Matsuda A, Maizel AL, Yamamoto H, Takeda A.

J Biol Chem. 1999 Jan 15;274(3):1407-14.

15.

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70.

Chen Z, Chen L, Qiao SW, Nagaishi T, Blumberg RS.

J Immunol. 2008 May 1;180(9):6085-93.

16.

The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model.

Ballek O, Valečka J, Manning J, Filipp D.

Immunol Cell Biol. 2015 Apr;93(4):384-95. doi: 10.1038/icb.2014.100. Epub 2014 Nov 25.

PMID:
25420722
17.

Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function.

Chan AC, Dalton M, Johnson R, Kong GH, Wang T, Thoma R, Kurosaki T.

EMBO J. 1995 Jun 1;14(11):2499-508.

18.

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

Hovis RR, Donovan JA, Musci MA, Motto DG, Goldman FD, Ross SE, Koretzky GA.

Science. 1993 Apr 23;260(5107):544-6.

PMID:
8475387
19.
20.

CD45 tyrosine phosphatase activity and membrane anchoring are required for T-cell antigen receptor signaling.

Niklinska BB, Hou D, June C, Weissman AM, Ashwell JD.

Mol Cell Biol. 1994 Dec;14(12):8078-84.

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