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Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2009 Sep 24;8:76. doi: 10.1186/1476-4598-8-76.


Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo.

Wei W, Chua MS, Grepper S, So S.

Int J Cancer. 2010 May 15;126(10):2426-36. doi: 10.1002/ijc.24810.


Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2011 Feb 11;10:16. doi: 10.1186/1476-4598-10-16.


Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402.

Zhao DH, Hong JJ, Guo SY, Yang RL, Yuan J, Wen CY, Zhou KY, Li CJ.

Cell Res. 2004 Feb;14(1):74-80.


Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells.

Qin X, Zhang H, Zhou X, Wang C, Zhang H, Zhang X, Ye L.

Transl Res. 2007 Nov;150(5):281-94. Epub 2007 Jul 18.


Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.

Chakraborty PK, Lee WK, Molitor M, Wolff NA, Thévenod F.

Mol Cancer. 2010 May 8;9:102. doi: 10.1186/1476-4598-9-102.


[Study on the role of Wnt/beta-catenin signaling transduction pathway in hepatocellular carcinoma cell line HepG2 and L02 cell line].

Wang QM, Jia LQ, Zhou HY, Li YS.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Oct;23(10):926-8. Chinese.


[Role of Wnt/beta-catenin signaling transduction pathway in rat hepatocarcinogenesis].

Wang QM, Li X, Jia LQ, Yang KM, Zhou HY, Yang HJ.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2006 Jul;22(4):454-7. Chinese.


Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis.

Kang DW, Lee SH, Yoon JW, Park WS, Choi KY, Min do S.

Cancer Res. 2010 May 15;70(10):4233-42. doi: 10.1158/0008-5472.CAN-09-3470. Epub 2010 May 4.


Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.

Yeh CT, Rao YK, Ye M, Wu WS, Chang TC, Wang LS, Wu CH, Wu AT, Tzeng YM.

Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41. doi: 10.1016/j.taap.2012.03.007. Epub 2012 Mar 23.


Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.

Renard CA, Labalette C, Armengol C, Cougot D, Wei Y, Cairo S, Pineau P, Neuveut C, de Reyniès A, Dejean A, Perret C, Buendia MA.

Cancer Res. 2007 Feb 1;67(3):901-10.


Novel candidate targets of Wnt/beta-catenin signaling in hepatoma cells.

Lee HS, Park MH, Yang SJ, Park KC, Kim NS, Kim YS, Kim DI, Yoo HS, Choi EJ, Yeom YI.

Life Sci. 2007 Jan 23;80(7):690-8. Epub 2006 Dec 6.


The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma.

Shiina H, Igawa M, Breault J, Ribeiro-Filho L, Pookot D, Urakami S, Terashima M, Deguchi M, Yamanaka M, Shirai M, Kaneuchi M, Kane CJ, Dahiya R.

Clin Cancer Res. 2003 Jun;9(6):2121-32.


Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma.

Hu J, Dong A, Fernandez-Ruiz V, Shan J, Kawa M, Martínez-Ansó E, Prieto J, Qian C.

Cancer Res. 2009 Sep 1;69(17):6951-9. doi: 10.1158/0008-5472.CAN-09-0541. Epub 2009 Aug 18.


Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC.

Yang F, Zeng Q, Yu G, Li S, Wang CY.

Cell Signal. 2006 May;18(5):679-87. Epub 2005 Aug 9.


ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.

Shin HW, Choi H, So D, Kim YI, Cho K, Chung HJ, Lee KH, Chun YS, Cho CH, Kang GH, Kim WH, Park JW.

Gastroenterology. 2014 Aug;147(2):430-442.e8. doi: 10.1053/j.gastro.2014.04.047. Epub 2014 May 15.


Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.

Torisu Y, Watanabe A, Nonaka A, Midorikawa Y, Makuuchi M, Shimamura T, Sugimura H, Niida A, Akiyama T, Iwanari H, Kodama T, Zeniya M, Aburatani H.

Cancer Sci. 2008 Jun;99(6):1139-46. doi: 10.1111/j.1349-7006.2008.00814.x. Epub 2008 Apr 21.


Redundant expression of canonical Wnt ligands in human breast cancer cell lines.

Benhaj K, Akcali KC, Ozturk M.

Oncol Rep. 2006 Mar;15(3):701-7.


Wnt-1 protein as a prognostic biomarker for hepatitis B-related and hepatitis C-related hepatocellular carcinoma after surgery.

Lee HH, Uen YH, Tian YF, Sun CS, Sheu MJ, Kuo HT, Koay LB, Lin CY, Tzeng CC, Cheng CJ, Tang LY, Tsai SL, Wang AH.

Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1562-9. doi: 10.1158/1055-9965.EPI-09-0039.

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