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Items: 1 to 20 of 482

1.

Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.

Leong GR, Goulding KR, Amin N, Richardson HE, Brumby AM.

BMC Biol. 2009 Sep 24;7:62. doi: 10.1186/1741-7007-7-62.

2.
3.

Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

Grzeschik NA, Parsons LM, Allott ML, Harvey KF, Richardson HE.

Curr Biol. 2010 Apr 13;20(7):573-81. doi: 10.1016/j.cub.2010.01.055. Epub 2010 Apr 1.

4.

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.

Andersen DS, Colombani J, Palmerini V, Chakrabandhu K, Boone E, Röthlisberger M, Toggweiler J, Basler K, Mapelli M, Hueber AO, Léopold P.

Nature. 2015 Jun 25;522(7557):482-6. doi: 10.1038/nature14298. Epub 2015 Apr 15.

PMID:
25874673
5.

The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia.

Warner SJ, Yashiro H, Longmore GD.

Curr Biol. 2010 Apr 27;20(8):677-86. doi: 10.1016/j.cub.2010.03.025. Epub 2010 Apr 8.

6.

Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.

Brumby AM, Goulding KR, Schlosser T, Loi S, Galea R, Khoo P, Bolden JE, Aigaki T, Humbert PO, Richardson HE.

Genetics. 2011 May;188(1):105-25. doi: 10.1534/genetics.111.127910. Epub 2011 Mar 2.

7.

Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant Cells.

Waghmare I, Kango-Singh M.

PLoS One. 2016 Jun 21;11(6):e0158081. doi: 10.1371/journal.pone.0158081. eCollection 2016.

8.

Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium.

Petzoldt AG, Gleixner EM, Fumagalli A, Vaccari T, Simons M.

Dis Model Mech. 2013 May;6(3):689-700. doi: 10.1242/dmm.010660. Epub 2013 Jan 18.

9.

The transcriptional response to tumorigenic polarity loss in Drosophila.

Bunker BD, Nellimoottil TT, Boileau RM, Classen AK, Bilder D.

Elife. 2015 Feb 26;4. doi: 10.7554/eLife.03189.

10.

The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization.

de Vreede G, Schoenfeld JD, Windler SL, Morrison H, Lu H, Bilder D.

Development. 2014 Jul;141(14):2796-802. doi: 10.1242/dev.105403.

11.

Kinase-activity-independent functions of atypical protein kinase C in Drosophila.

Kim S, Gailite I, Moussian B, Luschnig S, Goette M, Fricke K, Honemann-Capito M, Grubmüller H, Wodarz A.

J Cell Sci. 2009 Oct 15;122(Pt 20):3759-71. doi: 10.1242/jcs.052514. Epub 2009 Sep 29.

12.

Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium.

Fletcher GC, Lucas EP, Brain R, Tournier A, Thompson BJ.

Curr Biol. 2012 Jun 19;22(12):1116-22. doi: 10.1016/j.cub.2012.04.020. Epub 2012 May 31.

13.

A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis.

Jezowska B, Fernández BG, Amândio AR, Duarte P, Mendes C, Brás-Pereira C, Janody F.

Dev Biol. 2011 Dec 1;360(1):143-59. doi: 10.1016/j.ydbio.2011.09.016. Epub 2011 Sep 22.

14.

Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway.

Parsons LM, Grzeschik NA, Allott ML, Richardson HE.

Fly (Austin). 2010 Oct-Dec;4(4):288-93. Epub 2010 Oct 21. Review.

15.

Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded.

Robinson BS, Huang J, Hong Y, Moberg KH.

Curr Biol. 2010 Apr 13;20(7):582-90. doi: 10.1016/j.cub.2010.03.019. Epub 2010 Apr 1.

16.

The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth.

Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G.

J Cell Sci. 2009 Jul 15;122(Pt 14):2351-9. doi: 10.1242/jcs.046482. Epub 2009 Jun 16.

17.

Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy.

Külshammer E, Mundorf J, Kilinc M, Frommolt P, Wagle P, Uhlirova M.

Dis Model Mech. 2015 Oct 1;8(10):1279-93. doi: 10.1242/dmm.020719. Epub 2015 Aug 6.

18.

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling.

Dow LE, Elsum IA, King CL, Kinross KM, Richardson HE, Humbert PO.

Oncogene. 2008 Oct 9;27(46):5988-6001. doi: 10.1038/onc.2008.219. Epub 2008 Jul 21.

PMID:
18641685
19.

Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.

Igaki T, Pagliarini RA, Xu T.

Curr Biol. 2006 Jun 6;16(11):1139-46.

20.

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia.

Rolls MM, Albertson R, Shih HP, Lee CY, Doe CQ.

J Cell Biol. 2003 Dec 8;163(5):1089-98. Epub 2003 Dec 1.

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