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Items: 1 to 20 of 75

1.

2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities.

Kandadi MR, Rajanna PK, Unnikrishnan MK, Boddu SP, Hua Y, Li J, Du M, Ren J, Sreejayan N.

Biochem Pharmacol. 2010 Feb 15;79(4):623-31. doi: 10.1016/j.bcp.2009.09.018.

2.

Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo.

Ha BG, Yonezawa T, Son MJ, Woo JT, Ohba S, Chung UI, Yagasaki K.

Biofactors. 2014 Jul-Aug;40(4):436-47. doi: 10.1002/biof.1165. Epub 2014 Apr 23.

PMID:
24756979
3.

Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity.

Beck Jørgensen S, O'Neill HM, Hewitt K, Kemp BE, Steinberg GR.

Diabetologia. 2009 Nov;52(11):2395-404. doi: 10.1007/s00125-009-1483-8. Epub 2009 Aug 18. Erratum in: Diabetologia. 2010 Feb;53(2):398.

PMID:
19688337
4.

Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinase-dependent pathway that is impaired with obesity.

Steinberg GR, Watt MJ, Ernst M, Birnbaum MJ, Kemp BE, Jørgensen SB.

Diabetes. 2009 Apr;58(4):829-39. doi: 10.2337/db08-0659. Epub 2009 Jan 9.

5.

Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes and ob/ob mice.

Cheong SH, Furuhashi K, Ito K, Nagaoka M, Yonezawa T, Miura Y, Yagasaki K.

Mol Nutr Food Res. 2014 Feb;58(2):267-77. doi: 10.1002/mnfr.201300272. Epub 2013 Sep 3.

PMID:
24039053
6.

Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice.

Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR.

Diabetes. 2014 May;63(5):1560-71. doi: 10.2337/db13-0670. Epub 2014 Jan 31.

7.

Low molecular weight fucoidan improves endoplasmic reticulum stress-reduced insulin sensitivity through AMP-activated protein kinase activation in L6 myotubes and restores lipid homeostasis in a mouse model of type 2 diabetes.

Jeong YT, Kim YD, Jung YM, Park DC, Lee DS, Ku SK, Li X, Lu Y, Chao GH, Kim KJ, Lee JY, Baek MC, Kang W, Hwang SL, Chang HW.

Mol Pharmacol. 2013 Jul;84(1):147-57. doi: 10.1124/mol.113.085100. Epub 2013 May 8.

8.

Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice.

Lee YS, Cha BY, Choi SS, Harada Y, Choi BK, Yonezawa T, Teruya T, Nagai K, Woo JT.

Biofactors. 2012 Jul-Aug;38(4):300-8. doi: 10.1002/biof.1022. Epub 2012 Jun 2.

PMID:
22674784
9.

Chromium (D-phenylalanine)3 alleviates high fat-induced insulin resistance and lipid abnormalities.

Kandadi MR, Unnikrishnan MK, Warrier AK, Du M, Ren J, Sreejayan N.

J Inorg Biochem. 2011 Jan;105(1):58-62. doi: 10.1016/j.jinorgbio.2010.09.008.

10.

Rhizoma Anemarrhenae extract ameliorates hyperglycemia and insulin resistance via activation of AMP-activated protein kinase in diabetic rodents.

Han J, Yang N, Zhang F, Zhang C, Liang F, Xie W, Chen W.

J Ethnopharmacol. 2015 Aug 22;172:368-76. doi: 10.1016/j.jep.2015.05.016. Epub 2015 Jul 7.

11.

Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice.

Wang G, Xu X, Yao X, Zhu Z, Yu L, Chen L, Chen J, Shen X.

Diabetologia. 2013 Dec;56(12):2702-12. doi: 10.1007/s00125-013-3032-8. Epub 2013 Aug 29.

PMID:
23989723
12.

[D-LEU-4]-OB3, a synthetic leptin agonist, improves hyperglycemic control in C57BL/6J ob/ob mice.

Grasso P, Rozhavskaya-Arena M, Leinung MC, Lee DW.

Regul Pept. 2001 Sep 15;101(1-3):123-9.

PMID:
11495687
13.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

14.

Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus.

Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA.

Diabetologia. 2007 Aug;50(8):1723-31. Epub 2007 May 23.

PMID:
17520238
15.

Antidiabetic effects of pterosin A, a small-molecular-weight natural product, on diabetic mouse models.

Hsu FL, Huang CF, Chen YW, Yen YP, Wu CT, Uang BJ, Yang RS, Liu SH.

Diabetes. 2013 Feb;62(2):628-38. doi: 10.2337/db12-0585. Epub 2012 Oct 15.

16.

A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice.

Gao LH, Liu Q, Liu SN, Chen ZY, Li CN, Lei L, Sun SJ, Li LY, Liu JL, Shen ZF.

J Ethnopharmacol. 2014;151(1):675-85. doi: 10.1016/j.jep.2013.11.024. Epub 2013 Nov 25.

PMID:
24286962
17.

Antidiabetic and antiobesity effects of Ampkinone (6f), a novel small molecule activator of AMP-activated protein kinase.

Oh S, Kim SJ, Hwang JH, Lee HY, Ryu MJ, Park J, Kim SJ, Jo YS, Kim YK, Lee CH, Kweon KR, Shong M, Park SB.

J Med Chem. 2010 Oct 28;53(20):7405-13. doi: 10.1021/jm100565d.

PMID:
20873794
18.

5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.

Song XM, Fiedler M, Galuska D, Ryder JW, Fernström M, Chibalin AV, Wallberg-Henriksson H, Zierath JR.

Diabetologia. 2002 Jan;45(1):56-65.

PMID:
11845224
19.

Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice.

Huang SL, Yu RT, Gong J, Feng Y, Dai YL, Hu F, Hu YH, Tao YD, Leng Y.

Diabetologia. 2012 May;55(5):1469-81. doi: 10.1007/s00125-011-2366-3. Epub 2011 Nov 18.

PMID:
22095235
20.

Hypoglycemic effect of deoxynojirimycin-polysaccharide on high fat diet and streptozotocin-induced diabetic mice via regulation of hepatic glucose metabolism.

Li YG, Ji DF, Zhong S, Lin TB, Lv ZQ.

Chem Biol Interact. 2015 Jan 5;225:70-9. doi: 10.1016/j.cbi.2014.11.003. Epub 2014 Nov 20.

PMID:
25446853

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