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Items: 1 to 20 of 121

1.

Control of iron homeostasis by an iron-regulated ubiquitin ligase.

Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA.

Science. 2009 Oct 30;326(5953):718-21. doi: 10.1126/science.1176333. Epub 2009 Sep 17.

2.

An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis.

Salahudeen AA, Thompson JW, Ruiz JC, Ma HW, Kinch LN, Li Q, Grishin NV, Bruick RK.

Science. 2009 Oct 30;326(5953):722-6. doi: 10.1126/science.1176326. Epub 2009 Sep 17.

3.

Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.

Chollangi S, Thompson JW, Ruiz JC, Gardner KH, Bruick RK.

J Biol Chem. 2012 Jul 6;287(28):23710-7. doi: 10.1074/jbc.M112.360404. Epub 2012 May 30.

4.

F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis.

Ruiz JC, Walker SD, Anderson SA, Eisenstein RS, Bruick RK.

J Biol Chem. 2013 Jan 4;288(1):552-60. doi: 10.1074/jbc.M112.426171. Epub 2012 Nov 7.

5.

HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism.

Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI.

J Biol Chem. 2014 Jun 6;289(23):16430-41. doi: 10.1074/jbc.M113.541490. Epub 2014 Apr 28.

6.

Structural and molecular characterization of iron-sensing hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5).

Thompson JW, Salahudeen AA, Chollangi S, Ruiz JC, Brautigam CA, Makris TM, Lipscomb JD, Tomchick DR, Bruick RK.

J Biol Chem. 2012 Mar 2;287(10):7357-65. doi: 10.1074/jbc.M111.308684. Epub 2012 Jan 17.

7.

Cell biology. An ancient gauge for iron.

Rouault TA.

Science. 2009 Oct 30;326(5953):676-7. doi: 10.1126/science.1181938. No abstract available.

8.

A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation.

Johnson NB, Deck KM, Nizzi CP, Eisenstein RS.

J Biol Chem. 2017 Sep 22;292(38):15976-15989. doi: 10.1074/jbc.M117.785741. Epub 2017 Aug 2.

9.

F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen.

Ruiz JC, Bruick RK.

J Inorg Biochem. 2014 Apr;133:73-7. doi: 10.1016/j.jinorgbio.2014.01.015. Epub 2014 Jan 25. Review.

10.

Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.

Ponyeam W, Hagen T.

Cell Signal. 2012 Jan;24(1):290-5. doi: 10.1016/j.cellsig.2011.08.020. Epub 2011 Sep 16.

PMID:
21946088
11.
12.

Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.

Bornstein G, Ganoth D, Hershko A.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11515-20. Epub 2006 Jul 21.

13.

Influence of sodium nitroprusside on expressions of FBXL5 and IRP2 in SH-SY5Y cells.

Wei J, Li Y, Jiao Q, DU XX, Jiang H.

Sheng Li Xue Bao. 2017 Jun 25;69(3):261-266.

14.

Checks and balances for the iron bank.

Outten CE.

J Biol Chem. 2017 Sep 22;292(38):15990-15991. doi: 10.1074/jbc.H117.785741.

15.

FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response.

Chen ZW, Liu B, Tang NW, Xu YH, Ye XY, Li ZM, Niu XM, Shen SP, Lu S, Xu L.

Nucleic Acids Res. 2014 Oct;42(18):11560-9. doi: 10.1093/nar/gku876. Epub 2014 Sep 23.

17.

Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex.

Li HH, Kedar V, Zhang C, McDonough H, Arya R, Wang DZ, Patterson C.

J Clin Invest. 2004 Oct;114(8):1058-71.

18.

Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast.

Nakatsukasa K, Okumura F, Kamura T.

Crit Rev Biochem Mol Biol. 2015;50(6):489-502. doi: 10.3109/10409238.2015.1081869. Epub 2015 Sep 11. Review.

PMID:
26362128
19.

Protein degradation and iron homeostasis.

Thompson JW, Bruick RK.

Biochim Biophys Acta. 2012 Sep;1823(9):1484-90. doi: 10.1016/j.bbamcr.2012.02.003. Epub 2012 Feb 10. Review.

20.

Identification of Elongin C and Skp1 sequences that determine Cullin selection.

Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW.

J Biol Chem. 2004 Oct 8;279(41):43019-26. Epub 2004 Jul 27.

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