Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 115

1.

Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.

Carter RL, Fricks IP, Barrett MO, Burianek LE, Zhou Y, Ko H, Das A, Jacobson KA, Lazarowski ER, Harden TK.

Mol Pharmacol. 2009 Dec;76(6):1341-8. doi: 10.1124/mol.109.058578. Epub 2009 Sep 16.

2.

Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.

Fricks IP, Carter RL, Lazarowski ER, Harden TK.

J Pharmacol Exp Ther. 2009 Jul;330(1):162-8. doi: 10.1124/jpet.109.150730. Epub 2009 Apr 1.

3.

A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.

Barrett MO, Sesma JI, Ball CB, Jayasekara PS, Jacobson KA, Lazarowski ER, Harden TK.

Mol Pharmacol. 2013 Jul;84(1):41-9. doi: 10.1124/mol.113.085654. Epub 2013 Apr 16.

4.

Pharmacological effects mediated by UDP-glucose that are independent of P2Y14 receptor expression.

Scrivens M, Dickenson JM.

Pharmacol Res. 2005 Jun;51(6):533-8.

PMID:
15829433
5.

Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.

Qi AD, Harden TK, Nicholas RA.

J Pharmacol Exp Ther. 2013 Oct;347(1):38-46. doi: 10.1124/jpet.113.207647. Epub 2013 Aug 1.

6.

Functional expression of the P2Y14 receptor in human neutrophils.

Scrivens M, Dickenson JM.

Eur J Pharmacol. 2006 Aug 14;543(1-3):166-73. Epub 2006 Jun 7.

PMID:
16820147
7.

UDP is a competitive antagonist at the human P2Y14 receptor.

Fricks IP, Maddileti S, Carter RL, Lazarowski ER, Nicholas RA, Jacobson KA, Harden TK.

J Pharmacol Exp Ther. 2008 May;325(2):588-94. doi: 10.1124/jpet.108.136309. Epub 2008 Feb 5.

8.

Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.

Hamel M, Henault M, Hyjazie H, Morin N, Bayly C, Skorey K, Therien AG, Mancini J, Brideau C, Kargman S.

J Biomol Screen. 2011 Oct;16(9):1098-105. doi: 10.1177/1087057111415525. Epub 2011 Aug 5.

PMID:
21821827
9.

Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor.

Ko H, Fricks I, Ivanov AA, Harden TK, Jacobson KA.

J Med Chem. 2007 May 3;50(9):2030-9. Epub 2007 Apr 4.

12.

UDP-glucose acting at P2Y14 receptors is a mediator of mast cell degranulation.

Gao ZG, Ding Y, Jacobson KA.

Biochem Pharmacol. 2010 Mar 15;79(6):873-9. doi: 10.1016/j.bcp.2009.10.024. Epub 2009 Nov 5.

13.
14.

Thrombin-promoted release of UDP-glucose from human astrocytoma cells.

Kreda SM, Seminario-Vidal L, Heusden Cv, Lazarowski ER.

Br J Pharmacol. 2008 Apr;153(7):1528-37. doi: 10.1038/sj.bjp.0707692. Epub 2008 Jan 21.

15.

Pharmacological and second messenger signalling selectivities of cloned P2Y receptors.

Nicholas RA, Lazarowski ER, Watt WC, Li Q, Boyer J, Harden TK.

J Auton Pharmacol. 1996 Dec;16(6):319-23.

PMID:
9131407
16.

Geniposide attenuates inflammatory response by suppressing P2Y14 receptor and downstream ERK1/2 signaling pathway in oxygen and glucose deprivation-induced brain microvascular endothelial cells.

Li F, Li W, Li X, Li F, Zhang L, Wang B, Huang G, Guo X, Wan L, Liu Y, Zhang S, Kang S, Ma J.

J Ethnopharmacol. 2016 Jun 5;185:77-86. doi: 10.1016/j.jep.2016.03.025. Epub 2016 Mar 11.

PMID:
26976766
17.

The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways.

Hawes BE, Kil E, Green B, O'Neill K, Fried S, Graziano MP.

Endocrinology. 2000 Dec;141(12):4524-32.

PMID:
11108264
18.

The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism.

van der Westhuizen ET, Werry TD, Sexton PM, Summers RJ.

Mol Pharmacol. 2007 Jun;71(6):1618-29. Epub 2007 Mar 9.

19.

Receptor-independent activation of cardiac adenylyl cyclase by GDP and membrane-associated nucleoside diphosphate kinase. A new cardiotonic mechanism?

Niroomand F, Mura R, Jakobs KH, Rauch B, K├╝bler W.

J Mol Cell Cardiol. 1997 May;29(5):1479-86.

PMID:
9201632
20.

Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2.

Chu KM, Chow KB, Wong YH, Wise H.

Cell Signal. 2004 Apr;16(4):477-86.

PMID:
14709336

Supplemental Content

Support Center