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Items: 1 to 20 of 164

1.

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.

Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L.

J Biol Chem. 2009 Nov 6;284(45):31236-48. doi: 10.1074/jbc.M109.048694. Epub 2009 Sep 15.

2.

The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration.

Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L.

Development. 2011 Aug;138(15):3213-24. doi: 10.1242/dev.058693.

3.

Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas.

Mastracci TL, Anderson KR, Papizan JB, Sussel L.

PLoS Genet. 2013;9(2):e1003278. doi: 10.1371/journal.pgen.1003278. Epub 2013 Feb 7.

4.

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G.

Development. 2010 Jan;137(2):203-12. doi: 10.1242/dev.041673.

5.

Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells.

Chao CS, Loomis ZL, Lee JE, Sussel L.

Dev Biol. 2007 Dec 15;312(2):523-32. Epub 2007 Oct 5.

6.
7.

NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor.

Itkin-Ansari P, Marcora E, Geron I, Tyrberg B, Demeterco C, Hao E, Padilla C, Ratineau C, Leiter A, Lee JE, Levine F.

Dev Dyn. 2005 Jul;233(3):946-53.

9.

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.

Mellitzer G, Bonné S, Luco RF, Van De Casteele M, Lenne-Samuel N, Collombat P, Mansouri A, Lee J, Lan M, Pipeleers D, Nielsen FC, Ferrer J, Gradwohl G, Heimberg H.

EMBO J. 2006 Mar 22;25(6):1344-52. Epub 2006 Mar 2.

10.

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.

Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS.

Development. 2000 Aug;127(16):3533-42.

11.

Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas.

Mwangi SM, Usta Y, Raja SM, Anitha M, Chandrasekharan B, Parsadanian A, Sitaraman SV, Srinivasan S.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G283-92. doi: 10.1152/ajpgi.00096.2010. Epub 2010 May 6.

12.

Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.

Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B.

PLoS One. 2013 Aug 5;8(8):e70397. doi: 10.1371/journal.pone.0070397. Print 2013.

13.

Nkx2.2 regulates beta-cell function in the mature islet.

Doyle MJ, Sussel L.

Diabetes. 2007 Aug;56(8):1999-2007. Epub 2007 Apr 24.

14.

Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.

Gupta A, Wang Y, Browne C, Kim S, Case T, Paul M, Wills ML, Matusik RJ.

Prostate. 2008 Jan 1;68(1):50-60.

PMID:
18004726
15.

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.

Gradwohl G, Dierich A, LeMeur M, Guillemot F.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1607-11.

16.

Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.

Cai T, Chen X, Wang R, Xu H, You Y, Zhang T, Lan MS, Notkins AL.

Endocrinology. 2011 May;152(5):1961-9. doi: 10.1210/en.2010-1065. Epub 2011 Feb 22.

17.

Distinct gene expression programs function in progenitor and mature islet cells.

Watada H, Scheel DW, Leung J, German MS.

J Biol Chem. 2003 May 9;278(19):17130-40. Epub 2003 Feb 25.

18.

The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.

Kim SY, Rane SG.

Development. 2011 May;138(10):1903-12. doi: 10.1242/dev.061481. Epub 2011 Apr 13.

19.

Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation.

Zhang T, Wang H, Saunee NA, Breslin MB, Lan MS.

Endocrinology. 2010 May;151(5):2030-9. doi: 10.1210/en.2009-1224. Epub 2010 Mar 9.

20.

Contribution of a non-β-cell source to β-cell mass during pregnancy.

Toselli C, Hyslop CM, Hughes M, Natale DR, Santamaria P, Huang CT.

PLoS One. 2014 Jun 18;9(6):e100398. doi: 10.1371/journal.pone.0100398. eCollection 2014.

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