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Evidence for large diversity in the human transcriptome created by Alu RNA editing.

Barak M, Levanon EY, Eisenberg E, Paz N, Rechavi G, Church GM, Mehr R.

Nucleic Acids Res. 2009 Nov;37(20):6905-15. doi: 10.1093/nar/gkp729. Epub 2009 Sep 8.


Letter from the editor: Adenosine-to-inosine RNA editing in Alu repeats in the human genome.

Levanon K, Eisenberg E, Rechavi G, Levanon EY.

EMBO Rep. 2005 Sep;6(9):831-5. Review.


A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins.

Ensterö M, Akerborg O, Lundin D, Wang B, Furey TS, Ohman M, Lagergren J.

BMC Bioinformatics. 2010 Jan 4;11:6. doi: 10.1186/1471-2105-11-6.


Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome.

Athanasiadis A, Rich A, Maas S.

PLoS Biol. 2004 Dec;2(12):e391. Epub 2004 Nov 9.


Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats.

Kleinberger Y, Eisenberg E.

BMC Genomics. 2010 Jul 28;11:453. doi: 10.1186/1471-2164-11-453.


A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes.

Bazak L, Haviv A, Barak M, Jacob-Hirsch J, Deng P, Zhang R, Isaacs FJ, Rechavi G, Li JB, Eisenberg E, Levanon EY.

Genome Res. 2014 Mar;24(3):365-76. doi: 10.1101/gr.164749.113. Epub 2013 Dec 17.


Widespread cleavage of A-to-I hyperediting substrates.

Osenberg S, Dominissini D, Rechavi G, Eisenberg E.

RNA. 2009 Sep;15(9):1632-9. doi: 10.1261/rna.1581809. Epub 2009 Jul 21.


Alu elements shape the primate transcriptome by cis-regulation of RNA editing.

Daniel C, Silberberg G, Behm M, Öhman M.

Genome Biol. 2014 Feb 3;15(2):R28. doi: 10.1186/gb-2014-15-2-r28.


Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates.

Paz-Yaacov N, Levanon EY, Nevo E, Kinar Y, Harmelin A, Jacob-Hirsch J, Amariglio N, Eisenberg E, Rechavi G.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12174-9. doi: 10.1073/pnas.1006183107. Epub 2010 Jun 21.


Widespread RNA editing of embedded alu elements in the human transcriptome.

Kim DD, Kim TT, Walsh T, Kobayashi Y, Matise TC, Buyske S, Gabriel A.

Genome Res. 2004 Sep;14(9):1719-25.


Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats.

Greenberger S, Levanon EY, Paz-Yaacov N, Barzilai A, Safran M, Osenberg S, Amariglio N, Rechavi G, Eisenberg E.

BMC Genomics. 2010 Oct 28;11:608. doi: 10.1186/1471-2164-11-608.


Identification of widespread ultra-edited human RNAs.

Carmi S, Borukhov I, Levanon EY.

PLoS Genet. 2011 Oct;7(10):e1002317. doi: 10.1371/journal.pgen.1002317. Epub 2011 Oct 20.


Positive correlation between ADAR expression and its targets suggests a complex regulation mediated by RNA editing in the human brain.

Liscovitch N, Bazak L, Levanon EY, Chechik G.

RNA Biol. 2014;11(11):1447-56. doi: 10.4161/15476286.2014.992286.


Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing.

Osenberg S, Paz Yaacov N, Safran M, Moshkovitz S, Shtrichman R, Sherf O, Jacob-Hirsch J, Keshet G, Amariglio N, Itskovitz-Eldor J, Rechavi G.

PLoS One. 2010 Jun 21;5(6):e11173. doi: 10.1371/journal.pone.0011173.


One hundred million adenosine-to-inosine RNA editing sites: hearing through the noise.

Ulbricht RJ, Emeson RB.

Bioessays. 2014 Aug;36(8):730-5. doi: 10.1002/bies.201400055. Epub 2014 May 30.


Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing.

Li JB, Levanon EY, Yoon JK, Aach J, Xie B, Leproust E, Zhang K, Gao Y, Church GM.

Science. 2009 May 29;324(5931):1210-3. doi: 10.1126/science.1170995.


Accurate identification of human Alu and non-Alu RNA editing sites.

Ramaswami G, Lin W, Piskol R, Tan MH, Davis C, Li JB.

Nat Methods. 2012 Jun;9(6):579-81. doi: 10.1038/nmeth.1982. Epub 2012 Apr 4.


Possible editing of Alu transcripts in blood cells of sporadic Creutzfeldt-Jakob disease (sCJD).

Kiesel P, Gibson TJ, Ciesielczyk B, Bodemer M, Kaup FJ, Bodemer W, Zischler H, Zerr I.

J Toxicol Environ Health A. 2011;74(2-4):88-95. doi: 10.1080/15287394.2011.529057.


Altered adenosine-to-inosine RNA editing in human cancer.

Paz N, Levanon EY, Amariglio N, Heimberger AB, Ram Z, Constantini S, Barbash ZS, Adamsky K, Safran M, Hirschberg A, Krupsky M, Ben-Dov I, Cazacu S, Mikkelsen T, Brodie C, Eisenberg E, Rechavi G.

Genome Res. 2007 Nov;17(11):1586-95. Epub 2007 Oct 1.

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