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The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication.

Stepankiw N, Kaidow A, Boye E, Bates D.

Mol Microbiol. 2009 Oct;74(2):467-79. doi: 10.1111/j.1365-2958.2009.06877.x. Epub 2009 Sep 8.


A comprehensive set of DnaA-box mutations in the replication origin, oriC, of Escherichia coli.

Langer U, Richter S, Roth A, Weigel C, Messer W.

Mol Microbiol. 1996 Jul;21(2):301-11.


The DnaA box R4 in the minimal oriC is dispensable for initiation of Escherichia coli chromosome replication.

Bates DB, Asai T, Cao Y, Chambers MW, Cadwell GW, Boye E, Kogoma T.

Nucleic Acids Res. 1995 Aug 25;23(16):3119-25.


Loss of Hda activity stimulates replication initiation from I-box, but not R4 mutant origins in Escherichia coli.

Riber L, Fujimitsu K, Katayama T, Løbner-Olesen A.

Mol Microbiol. 2009 Jan;71(1):107-22. doi: 10.1111/j.1365-2958.2008.06516.x. Epub 2008 Nov 6.


Differentiation of the DnaA-oriC subcomplex for DNA unwinding in a replication initiation complex.

Ozaki S, Noguchi Y, Hayashi Y, Miyazaki E, Katayama T.

J Biol Chem. 2012 Oct 26;287(44):37458-71. doi: 10.1074/jbc.M112.372052. Epub 2012 Aug 31.


The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome.

Weigel C, Messer W, Preiss S, Welzeck M, Morigen, Boye E.

Mol Microbiol. 2001 Apr;40(2):498-507.


Competition between the replication initiator DnaA and the sequestration factor SeqA for binding to the hemimethylated chromosomal origin of E. coli in vitro.

Taghbalout A, Landoulsi A, Kern R, Yamazoe M, Hiraga S, Holland B, Kohiyama M, Malki A.

Genes Cells. 2000 Nov;5(11):873-884.


DnaA boxes are important elements in setting the initiation mass of Escherichia coli.

Christensen BB, Atlung T, Hansen FG.

J Bacteriol. 1999 May;181(9):2683-8.


Two oppositely oriented arrays of low-affinity recognition sites in oriC guide progressive binding of DnaA during Escherichia coli pre-RC assembly.

Rozgaja TA, Grimwade JE, Iqbal M, Czerwonka C, Vora M, Leonard AC.

Mol Microbiol. 2011 Oct;82(2):475-88. doi: 10.1111/j.1365-2958.2011.07827.x. Epub 2011 Sep 14.


The 245 base-pair oriC sequence of the E. coli chromosome directs bidirectional replication at an adjacent region.

Tabata S, Oka A, Sugimoto K, Takanami M, Yasuda S, Hirota Y.

Nucleic Acids Res. 1983 May 11;11(9):2617-26.


Architecture of bacterial replication initiation complexes: orisomes from four unrelated bacteria.

Zawilak-Pawlik A, Kois A, Majka J, Jakimowicz D, Smulczyk-Krawczyszyn A, Messer W, Zakrzewska-Czerwińska J.

Biochem J. 2005 Jul 15;389(Pt 2):471-81.


DnaA protein binding to individual DnaA boxes in the Escherichia coli replication origin, oriC.

Weigel C, Schmidt A, Rückert B, Lurz R, Messer W.

EMBO J. 1997 Nov 3;16(21):6574-83.


Topological characterization of the DnaA-oriC complex using single-molecule nanomanipuation.

Zorman S, Seitz H, Sclavi B, Strick TR.

Nucleic Acids Res. 2012 Aug;40(15):7375-83. doi: 10.1093/nar/gks371. Epub 2012 May 11.


Two discriminatory binding sites in the Escherichia coli replication origin are required for DNA strand opening by initiator DnaA-ATP.

McGarry KC, Ryan VT, Grimwade JE, Leonard AC.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2811-6. Epub 2004 Feb 20.


Assembly of Helicobacter pylori initiation complex is determined by sequence-specific and topology-sensitive DnaA-oriC interactions.

Donczew R, Mielke T, Jaworski P, Zakrzewska-Czerwińska J, Zawilak-Pawlik A.

J Mol Biol. 2014 Jul 29;426(15):2769-82. doi: 10.1016/j.jmb.2014.05.018. Epub 2014 May 24.


The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites.

Fuller RS, Funnell BE, Kornberg A.

Cell. 1984 Oct;38(3):889-900.


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